Science

CONTENTS NEWS IN BRIEF News at a glance NEWS IN DEPTH Israel’s grim warning: Delta can overwhelm shots Nazi massacre unearthed in Poland ‘was really a horror’ Laser-powered fusion effort nears ‘ignition’ Dire warming report triggers calls for more action from China Antibody acts like short-term malaria vaccine FEATURES Evolving threat Do chronic infections breed dangerous new variants? POLICY FORUM Keep climate policy focused on the social cost of carbon PERSPECTIVES The fracking concern with water quality Exploring the path of the variable resistance Tracking severe malaria disease Structural hierarchy defeats alloy cracking Ecology in the age of automation BOOKS ET AL . The children’s climate crusade Before the Big Bang became scientific dogma LETTERS Embrace kelp forests in the coming decade Mexico’s final death blow to the vaquita Piecing together an African peace park RESEARCH IN BRIEF From Science and other journals REVIEW Glaciohydrology of the Himalaya-Karakoram RESEARCH ARTICLES A DNA repair pathway can regulate transcriptional noise to promote cell fate transitions Accurate prediction of protein structures and interactions using a three-track neural network Mechanisms that ensure speed and fidelity in eukaryotic translation termination Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence REPORTS Large-sample evidence on the impact of unconventional oil and gas development on surface waters Stabilizing perovskite-substrate interfaces for high-performance perovskite modules Spatiotemporal characterization of the field-induced insulator-to-metal transition Hierarchical crack buffering triples ductility in eutectic herringbone high-entropy alloys Rare variant MX1 alleles increase human susceptibility to zoonotic H7N9 influenza virus Babbling in a vocal learning bat resembles human infant babbling Malaria infection and severe disease risks in Africa Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 DEPARTMENTS Editorial Working Life Science Staff Science Careers