RNA Interference

RNA interference (RNAi), a hallmark of all biological sciences of twenty-first century, is an evolutionarily conserved and double-stranded RNA-dependent eukaryotic cell defense process. Opportunity to utilize an organisms own gene and to systematically induce and trigger RNAi for any desired sequence made RNAi an efficient approach for functional genomics, providing a solution for conventional longstanding obstacles in life sciences. RNAi research and application have significantly advanced during past two decades. This book RNA interference provides an updated knowledge and progress on RNAi in various organisms, explaining basic principles, types, and property of inducers, structural modifications, delivery systems/methodologies, and various successful bench-to-field or clinic applications and disease therapies with some aspects of limitations, alternative tools, safety, and risk assessment. Chapter 1 RNA Interference – A Hallmark of Cellular Function and Gene Manipulation by Ibrokhim Y. Abdurakhmonov Chapter 2 RNA Interference Technology — Applications and Limitations by Devi Singh, Sarika Chaudhary, Rajendra Kumar, Preeti Sirohi, Kamiya Mehla, Anil Sirohi, Shashi Kumar, Pooran Chand and Pankaj Kumar Singh Chapter 3 The Role of Immune Modulatory MicroRNAs in Tumors by Barbara Seliger, Anne Meinhardt and Doerte Falke Chapter 4 Long Noncoding RNAs are Frontier Breakthrough of RNA World and RNAi-based Gene Regulation by Utpal Bhadra, Debabani Roy Chowdhury, Tanmoy Mondal and Manika Pal Bhadra Chapter 5 Noncanonical Synthetic RNAi Inducers by O.V. Gvozdeva and E.L. Chernolovskaya Chapter 6 Microinjection-Based RNA Interference Method in the Water Flea, Daphnia pulex and Daphnia magna by Kenji Toyota, Shinichi Miyagawa, Yukiko Ogino and Taisen Iguchi Chapter 7 ER-targeted Intrabodies Mediating Specific In Vivo Knockdown of Transitory Proteins in Comparison to RNAi by Oliver Backhaus and Thomas Böldicke Chapter 8 RNAi Therapeutic Potentials and Prospects in CNS Disease by Kyoung Joo Cho and Gyung Whan Kim Chapter 9 RNAi-based Gene Therapy for Blood Genetic Diseases by Mengyu Hu, Qiankun Ni, Yuxia Yang and Jianyuan Luo Chapter 10 Non-viral siRNA and shRNA Delivery Systems in Cancer Therapy by Emine Şalva, Ceyda Ekentok, Suna Özbaş Turan and Jülide Akbuğa Chapter 11 siRNA-Induced RNAi Therapy in Acute Kidney Injury by Cheng Yang and Bin Yang Chapter 12 Preclinical Development of RNAi-Inducing Oligonucleotide Therapeutics for Eye Diseases by Tamara Martínez, Maria Victoria González, Beatriz Vargas, Ana Isabel Jiménez and Covadonga Pañeda Chapter 13 RNAi-Induced Immunity by Wenyi Gu Chapter 14 Perspectives on RNA Interference in Immunopharmacology and Immunotherapy by Zhaohua Hou, Qiuju Han, Cai Zhang and Jian Zhang Chapter 15 RNA Interference as a Tool to Reduce the Risk of Rejection in Cell-Based Therapies by Constanca Figueiredo and Rainer Blasczyk Chapter 16 Utility of Potent Anti-viral MicroRNAs in Emerging Infectious Diseases by Zhabiz Golkar, Donald G. Pace and Omar Bagasra Chapter 17 RNAi — Implications in Entomological Research and Pest Control by Nidhi Thakur, Jaspreet Kaur Mundey and Santosh Kumar Upadhyay Chapter 18 Management of Insect Pest by RNAi — A New Tool for Crop Protection by Thais Barros Rodrigues and Antonio Figueira Chapter 19 RNA Interference – Natural Gene-Based Technology for Highly Specific Pest Control (HiSPeC) by Eduardo C. de Andrade and Wayne B. Hunter Chapter 20 RNA Interference – A Powerful Functional Analysis Tool for Studying Tick Biology and its Control by Remil Linggatong Galay, Rika Umemiya-Shirafuji, Masami Mochizuki, Kozo Fujisaki and Tetsuya Tanaka ave4eva 2016 Спизжено у ExLib: avxhome.se/blogs/exLib (Stole src from http://avxhome.se/blogs/exLib): tanas.olesya (avax); Snorgared,D3pZ4i & bhgvld,Denixxx (for softarchive) My gift to leosan==leonadin GasGeo&BioMedLover from ru-board :-) Спизжено у ExLib: avxhome.se/blogs/exLib (Stole src from http://avxhome.se/blogs/exLib):,tanas.olesya (avax),Snorgared,D3pZ4i & bhgvld,Denixxx,(for softarchive),My gift to leosan==leonadin GasGeo&BioMedLover from ru-board :-)