Reversing Human Aging

The first in-depth exploration of the exciting field of anti-aging medicine, Reversing Human Aging examines how aging starts and progresses through the body, the methods that medical scientists are devising to stop it, and what may happen when they succeed. Charts, graphs & illustrations. Michael Fossel, Ph.D., M.D. 1 HAS SCIENCE DISCOVERED THE TRUE FOUNTAIN OF YOUTH THAT WILL 1 REVERSING HUMAN AGING 2 Praise for Reversing Human Aging 2 HUMAN AGING 4 ACKNOWLEDGMENTS 7 CONTENTS 9 CHAPTER 8 TELLING TIMES 218 10 INTRODUCTION 11 LIFE 13 THE ENGINES OF AGING 35 OLD CELLS, OLD CHILDREN 59 THE GARDEN 65 THE CLOCK 73 OVERVIEW 84 HOW THE TELOMERE AFFECTS GENES 85 TELOMERE CHANGES 92 TISSUES AND ORGANS 98 SUMMARY 100 WHAT WE KNOW 103 A TROUT IN THE MILK 103 REVERSING AGING 103 ELEPHANTS AND MICE 107 INTRODUCTION 117 NORMAL HUMAN TISSUE 118 HUMAN CELLS IN DISEASE 125 DISEASES ASSOCIATED WITH SHORT TELOMERES 126 DISEASES OF INAPPROPRIATELY LONG TELOMERES 130 ALTERING HUMAN LIFE SPAN 131 TIME RUNS OUT 133 A CELL’S WORTH 140 BLOOD VESSELS 141 THE HEART 144 THE BRAIN 145 THE SKIN 147 THE GASTROINTESTINAL SYSTEM 149 THE KIDNEYS 150 THE LUNGS 150 THE MUSCULOSKELETAL SYSTEM: JOINTS, BONES, MUSCLES 152 THE ENDOCRINE SYSTEMS 154 THE IMMUNE SYSTEM 157 BETWEEN CELLS 159 TURNING BACK THE CLOCK 163 A NEW TIME 163 TREATING DISEASE 171 YOU 174 THE REWOUND CLOCK 188 DISEASES OF THE VESSELS 194 ARTHRITIS 196 THE IMMUNE SYSTEM 197 THE NERVOUS SYSTEM 198 THE SKIN 199 CANCER 200 PARASITIC DISEASES 202 THE DEMENTIAS 203 OTHER CONDITIONS 207 WILL LONGER TELOMERES CAUSE CANCER? 214 GERM CELL EFFECTS 216 SOMATIC CELL EFFECTS 216 MISMATCH EFFECTS 217 RESET EFFECTS 219 TELLING TIMES 228 THOUGHTS OF MALTHUS 233 CRIME AND VIOLENCE 248 THE WORLD 248 SOCIAL ROLES 249 SOCIAL INSTITUTIONS 251 LEGAL CHANGES 252 THE INDIVIDUAL 254 RELIGION 255 GLOSSARY 266 NOTES 269 Chapter 4: What We Know 274 Chapter 6: Turning Back the Clock 278 Chapter 7: The Rewound Clock 280 Chapter 8: Telling Times 283 BIBLIOGRAPHY 287 INDEX 297 E 304 101 304 202 305 122 306 K 309 L 309 M 309 N 311 P 311 u 316 w 316 X 317 Y 317