Renal Transport and Diuretics / Renaler Transport Und Diuretica : International Symposium Feldafing, June 21 – 23, 1968 / Internationales Symposium Feldafing, 21.–23. Juni 1968

It is generally appreciated that large congresses are not the optimal means of facilitating communication within specialized areas of medical research. Small symposia, where scientific discussion can be confined to limited groups, have lately become successful vehicles of information transfer. However, such symposia, although eminently suited to the exploration of specific problems, often have the llherent'disadvantage of not being able to successfully address themselves to larger themes. Accordingly, the planners of this symposium have solicited the parti­ cipation of internationally acclaimed investigators to consider current problems both in the physiological and clinical domains of nephrology. The observant reader will note that the variety of theoretical and experi­ mental approaches used by the physiologists are reflected in the clinical studies, while the clinicians, in turn, have provided the physiologists with useful insights. The part of the symposium which attempted to correlate metabolic characteristics of kidney cells with their transport functions has proven to be particularly fruitful. For example, the presentations dealing with aldosterone, angiotensin and diuretics have offered a multi-faceted approach that was previously unavailable. The contributions of investigators from many countries and their enthusiastic participation have led to the success of this symposium. To them we wish to express our deep gratitude. We also wish to sincerely thank Dr. K. H. BEYER, Senior Vice President of Merck, Sharp & Dohme Research Laboratories, and Dr. H. F. HOFMANN, Director of Medical Research of Sharp & Dohme GmbH for their full support and their constant attention to our many requests. Front Matter....Pages I-XV Renal Carbohydrate and Fatty Acid Metabolism....Pages 1-10 Renal Metabolism of Amino Acids and Ammonia....Pages 11-23 Transport of Ammonia in the Mammalian Cortical Nephron....Pages 25-28 Remarks on Renal Gaseous Metabolism....Pages 29-36 Relationship Between Cell Structures of Renal Tubules and Transport Mechanisms....Pages 37-65 The Role of Sodium and Potassium ATPase in Renal Sodium Reabsorption....Pages 67-76 The Coupling of Solute and Water Transport in Epithelia....Pages 77-98 Water Permeability of Different Nephron Segments in the Mammalian Kidney....Pages 99-107 Transport Characteristics of Isolated Perfused Proximal Tubules....Pages 109-121 The Regulation of Distal Tubular Potassium Transport....Pages 123-138 Intracellular Action of Aldosterone on Sodium Transport....Pages 139-152 Intrarenal Action of Steroid Hormones on Sodium Transport....Pages 153-172 Intrarenal Action of Angiotensin....Pages 173-184 The Effect of Angiotensin upon Blood Pressure Dependent Increases of Na- Excretion in Essential Hypertension....Pages 185-186 Countercurrent Considerations Relating to Renal Medullary pCO 2 and Bicarbonate Concentrations....Pages 187-193 Effects of Diuretics on Active Sodium Transport in Amphibian Membranes....Pages 195-208 The Effect of Diuretic Agents and Metabolic Inhibitors on O 2 -Consumption and Lactate Production of the Isolated Frog Skin....Pages 209-213 The Localization of Transport Processes in the Nephron and their Inhibition by Diuretic Agents as Analyzed by Micropuncture Techniques....Pages 215-228 The Pattern of Inhibition of Proximal Tubular Reabsorption by Diuretics....Pages 229-234 Present Status of Diuretic Therapy....Pages 235-246 Pharmacology of Antikaliuretic Substances....Pages 247-254 The Clinical Assessment of Diuretic Agents....Pages 255-268 Effects of Combined Application of Antikaliuretic Agents and Diuretics....Pages 269-300 On the Urinary Excretion of a New Antikaliuretic Agent....Pages 301-304 Serum Electrolytes During Combined Administration of Ethacrynic Acid and Amiloride....Pages 305-307 Clinical Results with Ethacrynic Acid in Combination with MK 870....Pages 309-312 Amiloride in Edematous Patients....Pages 313-316 The Action of Amiloride on the Sodium Transport at the Erythrocyte Membrane....Pages 317-319 Diuretics in the Treatment of Hypertension....Pages 321-335 The Treatment of Hypertension with Diuretics....Pages 337-352 The Importance of Diuretics for the Treatment of Hypertension....Pages 353-357 Natriuresis in Arterial Hypertension During Treatment with Saluretics....Pages 359-364 Diuretic Therapy in Patients with Cirrhosis....Pages 365-376 The Administration of Diuretics and the Metabolism of Aldosterone in Liver Disease....Pages 377-380 Clinical Application of Diuretics in Renal Disease....Pages 381-393 The Influence of Diuretics on the Fractional Fluid and Electrolyte-Excretion in Renal Insufficiency....Pages 395-402 Symptomatic Diuretic Therapy of the Nephrotic Edema with the Fixed Combination Ethacrynic Acid/Amiloride....Pages 403-407 The Application of Diuretics in Diabetes Insipidus....Pages 409-412 The Effect of Diuretics on the Extracorporeal Transplanted Kidney....Pages 413-419 Diuretics in Cardiac Diseases....Pages 421-431 Clinical Application of Diuretics in Cardiac Diseases....Pages 433-444 On the Use of Diuretics in Congestive Heart Failure....Pages 445-450 The Use of Diuretics in Cardiac Diseases....Pages 451-453 The Effect of Various Diuretics on Plasma Renin Activity in the Acute Experiment....Pages 455-458 Clinical Application of Diuretics During and After Heart Surgery....Pages 459-468 Diuretics in Cerebral Edema....Pages 469-481 Back Matter....Pages 483-487