Regulatory mechanisms in lymphocyte activation (Proceedings of the Leukocyte Culture Conference ; 11th)

Regulatory Mechanisms in Lymphocyte Activation covers the proceedings of the 11th Leukocyte Culture Conference, held at the Arizona Medical Center, University of Arizona on September 19-23, 1976. The contributors cover the various aspects of the conference theme''Regulatory Mechanisms in Lymphocyte Activation.''This book is organized into 15 parts encompassing 160 chapters. The three symposium parts discuss the parameters of lymphocyte activation, positive regulation, and suppression. Considerable sections explore the membrane determinants and receptors; major histocompatibility complex; lymphocyte response; and kinetics of DNA synthesis and cell proliferation in lymphocyte activation. Other general topics covered include subpopulations of immune reactive cells, leukocyte separation techniques, cell interactions, and ontogeny of lymphocytes. The remaining parts consider the leukocyte regulatory mechanisms and issues in lymphocytotoxicity. Immunologists and cell biologists will find this book invaluable. Content: ACADEMIC PRESS RAPID MANUSCRIPT REPRODUCTION , Page ii Front Matter , Page iii Copyright , Page iv LIST OF CONTRIBUTORS , Pages xix-xxxi PREFACE , Pages xxxiii-xxxiv , David O. Lucas ACKNOWLEDGMENTS , Page xxxv AN INTEGRATIVE APPROACH TO ACTIVATION AND SEQUENTIAL METABOLIC REGULATION OF THE IMMUNE RESPONSE , Pages 3-34 , David F. Ranney CATECHOLAMINE HORMONE RECEPTORS AND CELL DIVISION , Pages 35-50 , J.R. Sheppard, Sidneye Trowbridge, Elizabeth Anton, C.F. Moldow THE ROLE OF CATION FLUX IN TRIGGERING AND MAINTAINING THE STIMULATED STATE IN LYMPHOCYTES , Pages 51-75 , J.G. Kaplan PARAMETERS OF LYMPHOCYTE ACTIVATION , Pages 76-93 , David Lucas, Gary Klimpel RIBOSOME UTILIZATION AND REGULATION OF PROTEIN SYNTHESIS DURING LYMPHOCYTE ACTIVATION , Pages 94-113 , Herbert L. Cooper ROLE OF ADHERENT CELL PRODUCTS IN THE IMMUNE RESPONSE , Pages 117-136 , David D. Wood GENETIC REGULATION OF MACROPHAGE-T LYMPHOCYTE INTERACTION , Pages 137-151 , David W. Thomas, Ethan M. Shevach REGULATION OF B LYMPHOCYTES BY T CELL MEMBRANE GANGLIOSIDES , Pages 152-173 , Harold C. Miller, Barbara J. Laughter, Walter J. Esselman SPECIFIC AND NON-SPECIFIC ACTIVITIES IN DIALYZABLE TRANSFER FACTOR , Pages 174-192 , Charles H. Kirkpatrick, Terrill K. Smith MAINTENANCE OF THE RESTING STATE AND POTENTIAL REGULATORS OF THE PROLIFERATIVE PHASE , Pages 195-218 , Dennis E. Lopatin, David F. Ranney SERUM FACTORS WHICH SUPPRESS THE IMMUNE RESPONSE , Pages 219-250 , Thomas B. Tomasi Jr. SUPPRESSION OF IMMUNE RESPONSES BY PRODUCTS OF ACTIVATED T CELLS , Pages 251-268 , Robert R. Rich, Susan Solliday Rich DYSFUNCTION OF SUPPRESSOR MECHANISMS ASSOCIATED WITH IMMUNODEFICIENCY AND AUTOIMMUNITY , Pages 269-287 , T.A. Waldmann, S. Broder, R. Krakauer, M. Durm, C. Goldman, B. Meade, W. Strober IMMUNOSUBVERSIVE ACTIVITY OF TUMOR CELLS AS AN ESCAPE MECHANISM , Pages 288-310 , Otto J. Plescia, Kazimiera Grinwich, Alan Smith, John Sheridan, Anne M. Plescia T CELL ACTIVATION INDUCED BY CROSS-LINKING OF ANTI-T CELL DIRECTED ANTIBODIES WITH ANTI-IMMUNOGLOBULIN , Pages 313-315 , W.T. Weber CONCANAVALIN A INDUCED TRIGGERING OF ALLOSENSITIZED MEMORY LYMPHOCYTES INTO SECONDARY CYTOTOXIC LYMPHOCYTES , Pages 316-318 , Benjamin Bonavida IDENTIFICATION AND CHARACTERIZATION OF THE CHEMICAL MOIETY OF LPS RESPONSIBLE FOR C3H/HeJ SPLEEN CELL MITOGENICITY , Pages 319-321 , Sally J. Betz, David C. Morrison, Diane M. Jacobs ISOLATION OF A MITOGENIC PROTEIN FROM WHEAT GERM WITH THE SAME SPECIFICITY FOR THE LYMPHOCYTE MEMBRANE AS WHEAT GERM AGGLUTININ , Pages 322-324 , John M. Brown, Myron A. Leon, James J. Lightbody A RECEPTOR FOR NORMAL HUMAN SERUM LOW DENSITY LIPOPROTEINS ON PERIPHERAL BLOOD LYMPHOCYTES , Pages 325-327 , Linda K. Curtiss, Thomas S. Edgington CHARACTERIZATION OF THE MOUSE LYMPHOCYTE RECEPTOR FOR HUMAN β 2 -MICROGLOBULIN , Pages 328-330 , Raymond B. Hester, Ralph T. Kubo, Howard M. Grey MECHANISM OF ANTI-μ INDUCED SUPPRESSION OF LPS INDUCED IMMUNOGLOBULIN SYNTHESIS , Pages 331-333 , J,K. Kearney, A.R. Lawton, J. Klein, D.E. Bockman, M.D. Cooper THE MECHANISM OF FC RECEPTOR-MEDIATED INHIBITION OF B LYMPHOCYTE ACTIVATION BY ANTIGEN , Pages 334-336 , M.F. La Via, R.L. Roberts Jr., D.S. La Via DECREASED RESPONSIVENESS OF LYMPHOCYTES TAGGED WITH DINITROFLUOROBENZENE (DNFB) TO PHYTOMITOGENS , Pages 337-339 , Rolf F. Barth, K.R. Madyastha, P.R. Madyastha INHIBITION OF MACROPHAGE-INDUCED THYMIC LYMPHOCYTE MATURATION BY CYTOCHALASIN B , Pages 340-342 , Jan G. vanden Tweel, Dienne Elferink, Tinekevande Berg, William S. Walker THE INSULIN RECEPTOR ON THE T CELL: A MARKER OF ACTIVATION AFTER STIMULATION , Pages 343-345 , J. Harold Helderman, Terry B. Strom A ROSETTE MARKER FOR MITOGEN ACTIVATED HUMAN LYMPHOCYTES , Pages 346-348 , David Tak Yan Yu, Amelia Kacena, Carl M. Pearson LABELING OF HUMAN LEUKOCYTE SURFACE RECEPTORS WITH MICROSPHERES, IN GIEMSA STAINED PREPARATIONS , Pages 349-351 , Ian L. Gordon, Clive R. Taylor, Richard L. O'Brien, John W. Parker STUDIES ON THE HUMAN T LYMPHOCYTE – SHEEP ERYTHROCYTE RECEPTOR , Page 352 , F.V. Chisari RE-EVALUATION OF RECEPTORS FOR IgG ON HUMAN LYMPHOCYTES , Pages 353-355 , Philip J. Clements, Joshua Levy RABBIT T AND B LYMPHOCYTES:SURFACE MARKERS AND FUNCTIONAL CHARACTERISTICS , Pages 356-358 , Clara Bell, Hans Wigzell REACTIONS OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES WITH C5b-9 COMPLEMENT COMPLEX-SPECIFIC ANTIBODIES , Pages 359-361 , J.S. Sundsmo, W.P. Kolb, H.J. Muller-Eberhard IDENTIFICATION OF HUMAN LYMPHOCYTE SUBPOPULATIONS BY RAPID MICROROSETTE TECHNIQUE , Pages 362-364 , M. Suthanthiran, M.R. Garovoy, G. St. Louis, G. Fagan, J. Paradysz, C.B. Carpenter SEPARATION METHODS, SURFACE MARKERS AND CYTOTOXIC CAPABILITIES OF HUMAN EOSINOPHILS , Pages 365-367 , Joseph E. Parrillo, Anthony S. Fauci EFFECT OF FICOLL-HYPAQUE SEPARATION ON ACTIVATION AND DNA SYNTHESIS OF HUMAN BLOOD LYMPHOCYTES , Pages 368-370 , Patricia Fames, Barbara E. Barker AUGMENTATION OF IN VITRO GENERATED CELL MEDIATED CYTOTOXICITY BY NEURAMINIDASE , Pages 371-373 , Ronald M. Ferguson, Susan M. Anderson, Jon R. Schmidtke, Richard L. Simmons ISOLATION OF TUMOR ASSOCIATED ANTIGEN (S) FROM A MOLONEY VIRUS INDUCED LEUKEMIA (MBL-2) , Pages 374-376 , A.K. Ng, K.R. McIntire, J.A. Braatz, R.B. Herberman EXPRESSION OF H-2 SPECIFICITIES AND OF MuLV ENVELOPE ANTIGENS ON MURINE TUMORS , Pages 379-381 , V. Schirrmacher, F. Garrido ANTIGEN MAPPING FOR T CELL RECOGNITION: IMMUNE RESPONSE GENE CONTROL OF DETERMINANT SELECTION , Pages 382-384 , Marcello A. Barcinski, Alan S. Rosenthal SPECIFICITY OF ANAMNESTIC RESPONSIVENESS IN VITRO TO ANTIGENS UNDER HISTOCOMPATIBILITY-LINKED IR GENE CONTROL IN RATS , Pages 385-387 , Eberhard Günther, Erwin Rüde, Joachim Metzger THE TYN-PLOP PHENOMENON IN HLA-D TYPING , Pages 388-390 , A. Termijtelen, B.A. Bradley, J.J. van Rood MLR INHIBITION, HLA-D TYPING USING HOMOZYGOUS TYPING CELLS AND IN “VITRO” PRIMED LYMPHOCYTES VERSUS A B CELL SPECIFIC ANTIGENIC SYSTEM , Pages 391-393 , M. Sasportes, P. Crosier, C. Mawas, D. Charmot, L. Legrand, J. Dausset PRIMED LD TYPING: ANALYSIS OF THE HLA-D COMPLEX , Pages 394-396 , B.J. Alter, G. Gordon, E. Jarrett-Toth, F.H. Bach, P. Wernet IN VITRO STIMULATION OF UNPRIMED LYMPHOCYTES BY ALLOGENEIC SEMI-SOLUBLE LYMPHOCYTE MEMBRANE FRAGMENTS , Pages 397-399 , A. Kaldany, A.P. Lundin III, K. George, M. Suthanthiran, M.R. Garovoy, C.B. Carpenter, T.B. Strom THE PRIMED CANINE MLC: ALLOGRAFT IMMUNITY IN VITRO , Pages 400-402 , J. Lifton, W.C. DeWolf, C. Wilcox, J. Miller PRIMARY IN VITRO SENSITIZATION OF ISOGENEIC AND ALLOGENEIC MURINE LYMPHOCYTES TO NORMAL AND SV40-TRANSFORMED BALB/c 3T3 CELLS , Pages 403-405 , Takashi Maki, Michael L. Howe EXTRACTION OF Ia-LIKE ANTIGEN FROM CULTURED HUMAN B LYMPHOBLASTS AND ITS EXPRESSION ON LEUKEMIC CELLS , Pages 406-408 , Arthur K. Sullivan, L. Martin Jerry, Geoffrey Rowden, Harold N. Rode, Julius Gordon, Hien Le Thi, Mary Shea WORKSHOP ON H-2 RESTRICTION OF T CELL FUNCTION , Pages 411-414 , Michael Howe, Fernando Plata PROCESSING OF LPS BY CELLS COMPETENT TO RESPOND: CONVERSION TO A LOW MOLECULAR WEIGHT FORM STRONGLY MITOGENIC FOR C 3 H/HeJ LOW RESPONDERS , Pages 417-419 , J.G. Kaplan, Paolo Truffa-Bachi, Constantin Bona MITOGENICITY OF DERIVATIVES OF THE LIPOPROTEIN FROM THE OUTER MEMBRANE OF ESCHERICHIA COLI , Pages 420-422 , Wolfgang G. Bessler, Klaus Hantke LYMPHOCYTE SURFACE GLYCOSYLTRANSFERASES , Pages 423-425 , Robert O. Endres, David O. Lucas FUNCTIONAL MOSAICISM OF THE LYMPHOCYTE PLASMA MEMBRANE , Pages 426-428 , Klaus Resch, Alois Lorarcher, Bernd Mähler, Michael Stoeck, Harold N. Rode THE SPECIFICITY OF CON A – INDUCED DECREASE IN LYMPHOCYTE POTASSIUM , Pages 429-431 , W. Negendank, C. Shaller TRANSMEMBRANE K + TURNOVER BY PHYTOHEMAGGLUTININ (PHA) – STIMULATED HUMAN LYMPHOCYTES , Pages 432-434 , G.B. Segel, M.A. Lichtman DIFFERENTIAL ALTERATION OF MEMBRANE TRANSPORT IN NON-ADHERENT SPLEEN CELLS FROM CON-A STIMULATED MICE , Pages 435-437 , Phyllis R. Strauss, James M. Sheehan, Eva R. Kashket EFFECT OF THE IONOPHORE A23187 UPON LYMPHOCYTE CALCIUM METABOLISM , Pages 438-440 , Pamela Jensen, Howard Rasmussen CHANGES N THE LIPID COMPONENTS OF STIMULATED HUMAN LYMPHOCYTES , Pages 441-443 , M.C.A. Puntis Fc RECEPTOR MEDIATED INCREASES IN INTRACELLULAR cAMP , Pages 444-446 , John L. Ryan, Pierre A. Henkart A SINGLE SECOND SIGNAL FOR MITOGENESIS? , Pages 447-449 , Ginger W. Miller, Edward J. Moticka SYNTHESIS OF ALBUMIN BY RABBIT LYMPHOID CELLS , Pages 450-452 , Marius Teodorescu, Mary Jo DeBates, Sheldon Dray IN VITRO MODULATION OF PHYTOHEMAGGLUTININ-P INDUCED BLASTOGENESIS BY PARATHYROID HORMONE , Pages 453-455 , M. Hoette, A. Kaldany, A.P. Lundin III, M.N. Gottlieb, M. Suthanthiran, C.B. Carpenter, T.B. Strom EVIDENCE FOR AN EARLY SULFHYDRYL REAGENT SENSITIVE STEP DURING LYMPHOCYTE ACTIVATION , Pages 456-458 , H.J. Wedner, D.D. Chaplin, C.W. Parker FACTORS INFLUENCING STIMULATION AND PROLIFERATION IN MITOGEN STIMULATED THYMOCYTES , Pages 459-460 , Ido Betel, Gerardvanden Westen, Joke Martijnse FACTORS AFFECTING THE MEASUREMENT AND INTERPRETATION OF IN VITRO LYMPHOCYTE REACTIVITY , Pages 461-463 , Carleton C. Stewart, Barbara Hamill PITFALLS IN THE LYMPHOCYTE PROLIFERATION ASSAY: VARIATIONS IN PROLIFERATION KINETICS AND COLD THYMIDINE POOLS , Pages 464-466 , Jan L. Bernheim, Randel Dorian, John Mendelsohn IS THERE GENE AMPLIFICATION OR OTHER NONDUPLICATIVE DNA SYNTHESIS IN HUMAN LYMPHOCYTE ACTIVATION? , Pages 467-469 , John Mendelsohn, Randel Dorian, Jan Castagnola, Jan Bernheim CELLULAR COOPERATION IN THE RELEASE OF DNA BY HUMAN LYMPHOCYTES , Pages 470-472 , David H. Boldt, Geoffrey S. Nash, Stephen F. Speckart, Richard P. MacDermott INTERMEDIATES OF DNA SYNTHESIS OF MOUSE THYMOCYTES , Pages 473-475 , M. Lanotte, C. Moerman, J. Panijel KINETICS OF DNA SYNTHESIS AND CELL PROLIFERATION IN LYMPHOCYTE ACTIVATION: WORKSHOP REVIEW , Pages 479-505 , Jan L. Bernheim, John Mendelsohn ANALYSIS OF SURFACE PROPERTIES, FINE STRUCTURE AND ORGAN DISTRIBUTION OF TWO DISTINCT T-CELL SUBPOPULATIONS: Tμ AND Tγ , Pages 509-511 , C.E. Grossi, L. Moretta, S.R. Webb, M.C. Mingari, A. Moretta, P.M. Lydyard, A. Zicca, M.D. Cooper PROLIFERATIVE RESPONSIVENESS OF TWO DISTINCT HUMAN T-CELL SUBPOPULATIONS TO CON A, PHA AND ALLOANTIGENS , Pages 512-514 , S.R. Webb, P.M. Lydyard, L. Moretta, M. Ferrarini, M.C. Mingari, A. Moretta, M.D. Cooper SEPARATION OF TUMOR ENHANCING MURINE THYMOCYTES BY AGGLUTINATION WITH A PEANUT LECTIN (PNA) , Pages 515-517 , M. Linker-Israeli, M. Itzchaki, T. Umiel, N. Trainin, N. Sharon SPONTANEOUS CYTOTOXICITY BY HUMAN PERIPHERAL BLOOD LYMPHOCYTES , Pages 518-520 , David L. Nelson, Bonita M. Bundy, Warren Strober STUDIES OF MONOCYTE Fc RECEPTOR AVIDITY AND MONOCYTE MEDIATED ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY (MMADCC) IN MAN , Pages 521-523 , E.C. Lawrence, D.G. Poplack, B.J. Holiman, N.D. Dooley, I.R. Koski, R.M. Blaese BINDING OF IMMUNOGLOBULIN-BEARING LYMPHOID CELLS TO ALLOGENEIC AND SYNGENEIC TARGET CELLS , Pages 524-526 , Gideon Berke ANTIBODY DEPENDENT CELL MEDIATED CYTOTOXICITY (ADCC) IN SEVERE COMBINED IMMUNODEFICIENCY (SCID) , Pages 527-529 , Raif S. Geha CHARACTERIZATION OF THE EFFECTOR CELL IN AN ANTIBODY DEPENDENT CELL MEDIATED CYTOTOXICITY SYSTEM , Pages 530-532 , David S. Gordon, Steven L. Shore REGENERATION AND PROLIFERATION IN VITRO OF CYTOLYTIC T LYMPHOCYTES SPECIFIC FOR MSV-ASSOCIATED TUMOR ANTIGENS , Pages 533-535 , Fernando Plata, C. Victor Jongeneel CYTOTOXICITY OF HUMAN LYMPHOCYTES IN CELL-MEDIATED LYMPHOLYSIS (CML) AND ANTIBODY-DEPENDENT LYMPHOCYTOTOXICITY (ADL) , Pages 536-538 , W.P. Zeijlemaker, M.H.J. van Oers, R.E.Y. de Goede DIFFERENT MECHANISMS FOR NATURAL KILLER (NK) AND ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY (ADCC) BY Fc-RECEPTOR BEARING LYMPHOCYTES , Pages 539-541 , H. David Kay, William H. West, Guy D. Bonnard IN VITRO INDUCTION OF NATURAL KILLER (NK) AND KILLER (K) CELLS , Pages 542-544 , J.R. Ortaldo, H.D. Kay, G.D. Bonnard IS THERE A RELATIONSHIP BETWEEN EFFECTOR-TARGET CELL BINDING AND CELL-MEDIATED CYTOTOXICITY? , Pages 545-547 , Elizabeth Ann Grimm, Benjamin Bonavida MECHANISMS OF TARGET CELL KILLING BY ACTIVATED LYMPHOCYTES IN VITRO , Pages 548-550 , Vera Stejskal, Gerd R. Pape, Peter Perlmann IDENTIFICATION OF LYMFHOTOXIN (LT) AS THE MEDIATOR OF DIRECT CYTOLYS IS OF L-929 CELLS BY MITOGEN ACTIVATED HUMAN LYMPHOCYTES IN VITRO , Pages 551-553 , John C. Hiserodt, Carl F. Ware, Gale A. Granger FRACTIONATION OF HUMAN LYMPHOCYTES ON LINEAR DENSITY GRADIENTS , Pages 554-556 , Karen Zier, Christoph Huber, Herbert Braunsteiner PRIMARY IN VITRO ANTIBODY RESPONSE FROM HUMAN PERIPHERAL BLOOD LYMPHOCYTES , Pages 557-559 , P. Galanaud, J.F. Delfraissy, J. Dormont, Ch. Wallon PLAQUE FORMING CELL ASSAY FOR THE MEASUREMENT OF POLYCLONAL ACTIVATION OF HUMAN PERIPHERAL BLOOD LYMPHOCYTES. CELLULAR REQUIREMENTS AND INTERACTIONS , Pages 560-562 , Anthony S. Fauci, Karen R. Pratt EFFECT OF ANTIGEN ON LOCALIZATION OF IMMUNOLOGICALLY SPECIFIC B CELLS , Pages 563-565 , N.M. Ponzio, G.J. Thorbecke IDENTIFICATION OF FIVE HUMAN LYMPHOCYTE SUBPOPULATIONS BY DIFFERENTIAL LABELING WITH BACTERIA , Pages 566-568 , Marius Teodorescu, Eugene P. Mayer, Sheldon Dray THE TOXICITY OF CYCLOPHOSPHAMIDE FOR T AND B CELLS , Pages 569-571 , A. Winkelstein, R. Neta, S.B. Salvin IN VITRO GROWTH OF CANINE AND MURINE GRANULOCYTE-MONOCYTE, FIBROBLAST AND LYMPHOCYTE COLONIES: PRELIMINARY RESULTS , Pages 572-574 , F.D. Wilson, M. Shifrine, M.E. Gershwin WORKSHOP ON LEUKOCYTE SEPARATION TECHNIQUES , Pages 577-578 , Jack H. Dean A CRITIQUE OF TECHNIQUES OF MACROPHAGE-MONOCYTE DEPLETION IN STUDIES OF HUMAN PERIPHERAL BLOOD MONONUCLEAR LEUKOCYTE (MNL) FUNCTION , Pages 579-582 , R. Michael Blaese, E. Clinton Lawrence, David G. Poplack TECHNICAL CONSIDERATIONS FOR THE SEPARATION OF HUMAN PERIPHERAL BLOOD LYMPHOCYTE SUBPOPULATIONS BY ROSETTING WITH SHEEP ERYTHROCYTE , Pages 583-586 , Jack H. Dean, Antoine Kibrite, Thomas R. Jerrells, Ronald B. Herberman MODIFICATIONS OF ANTI-Fab IMMUNOABSORBENT SEPARATION OF HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS , Pages 587-590 , David L. Nelson, Richard P. MacDermott SEPARATION OF HUMAN LYMPHOCYTES BY THEIR Fc RECEPTOR , Pages 591-593 , Pierre A. Henkart WORKSHOP CONCLUSIONS , Pages 594-596 , Jack H. Dean GENERATION OF CYTOTOXIC T CELLS REQUIRES ANTIGEN-SPECIFIC HELPER T CELLS , Pages 599-601 , Linda M. Pilarski IN VITRO INDUCTION AND ASSAY OF HELPER T-CELLS USING UNPRIMED PURIFIED MOUSE CELL POPULATIONS , Pages 602-604 , J.S. McDougal, David S. Gordon PERIODATE-INDUCED BLAST TRANSFORMATION IN MIXTURES OF RAT LYMPHOID CELLS , Pages 605-607 , W.E. Bowers, C.F. Beyer ENHANCEMENT OF WEAK MLC TYPE REACTIONS BY HYDROPHILIC POLYMERS , Pages 608-610 , Shmuel A. Ben-Sasson, Pierre A. Henkart ROLE OF RAT LYMPHOCYTE SUBPOPULATIONS IN THE MIXED LYMPHOCYTE CULTURE (MLC) , Pages 611-613 , A.P. Lundin III, A. Kaldany, T.B. Strom, J.P. Soulillou, C.B. Carpenter INHIBITION OF THE HUMAN MIXED LYMPHOCYTE CULTURE (MLC) INTERACTION BY CYTOTOXIC AGENTS CONJUGATED TO ANTI-LYMPHOCYTE GLOBULIN , Pages 614-616 , Henry Hirschberg, Erik Thorsby, George Rowland VIRUS-MACROPHAGE-LYMPHOCYTE INTERACTIONS , Pages 617-619 , H. Kirchner, G. Darai, K. Keyssner, K. Munk, S.E. Mergenhagen WORKSHOP ON MACROPHAGE-LYMPHOCYTE INTERACTION , Pages 623-625 , David L. Rosenstreich, Joost J. Oppenheim THYMOSIN-INDUCED ENHANCEMENT OF MIF PRODUCTION BY PERIPHERAL BLOOD LYMPHOCYTES OF THYMECTOMIZED GUINEA PIGS , Pages 629-631 , Gary B. Thurman, Jeffrey L. Rossio, Allan L. Goldstein T CELL FUNCTION IN CONGENITALLY ASPLENIC (Dh/+) MICE , Pages 632-634 , Mark P. Fletcher, Richard Ikeda, M. Eric Gershwin INTERACTIONS OF HUMAN NEONATAL T AND B LYMPHOCYTES AND EVIDENCE FOR FUNCTIONAL IMMATURITY , Pages 635-637 , A.R. Hayward, A.R. Lawton CELL-MEDIATED LYMPHOLYSIS BY HUMAN NEONATAL LYMPHOCYTES , Pages 638-640 , Paavo Toivanen, Christer Granberg, Kimmo Manninen TO THE QUESTION OF NULL CELLS IN THE AVIAN BURSA OF FABRICIUS , Pages 641-643 , W.T. Weber SPONTANEOUS CYTOTOXICITY BY HUMAN PERIPHERAL BLOOD LYMPHOCYTES DUE TO A TIME DEPENDENT LOSS OF SUPPRESSOR CELLS , Pages 647-649 , Andrew V. Muchmore, Jean M. Decker, R. Michael Blaese REGENERATION OF EFFECTOR FUNCTION IN VITRO , Pages 650-652 , W.R. Clark, D. Heininger, M. Touton, A.K. Chakravarty ROLE OF H-2 CD ANTIGENS IN SECONDARY RESPONSES , Pages 653-655 , C. Grillot-Courvalin, B.J. Alter, F.H. Bach ANALYSIS OF SECONDARY MLR BY TITRATION OF IN VITRO PRIMED HUMAN LYMPHOCYTES , Pages 656-658 , Ronald B. Corley, Rita Zimmermann ENHANCEMENT OF PINOCYTOSIS IN THE MACROPHAGE BY MACROPHAGE ACTIVATING FACTOR , Pages 659-661 , Richard D. Schubert, John R. David MIGRATION OF NORMAL HUMAN LYMPHOCYTES CULTURED IN THE PRESENCE OF CANDIDA ALBICANS EXTRACT , Pages 662-664 , Marilyn C. Sutcliffe, J. Richard Graybill, Robert H. Alford MECHANISM OF LEUKOCYTE ADHERENCE INHIBITION , Pages 665-667 , Takeshi Yoshida MODULATION OF HUMAN EA ROSETTE FORMATION AND ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY BY PROMETHAZINE AND AGENTS WHICH ALTER CYCLIC NUCLEOTIDE LEVELS , Pages 668-670 , S.C. Wright, P.E. Hurtubise CELLULAR CYTOTOXICITY INDUCED BY CALCIUM IONOPHORE A23187 , Pages 671-673 , Richard P. MacDermott, Geoffrey S. Nash THE ROLE OF OPSONINS IN PHAGOCYTOSIS AND INTRACELLULAR KILLING OF GRAM-NEGATIVE BACTERIA BY HUMAN POLYMORPHONUCLEAR LEUKOCYTES (PMN) , Pages 674-676 , J. Menzel, H. Jungfer, D. Gemsa SPONTANEOUS LYMPHOCYTE PROLIFERATION IN HODGKIN'S DISEASE , Pages 677-679 , Thomas A. Shiftan, Alendry P. Caviles Jr., John Mendelsohn ACTIVATION OF ISOLATED T CELLS IN CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) BY MITOGENS , Pages 680-682 , H. Rühl, H. Scholle, G. Bochert, U. Rühl, W. Vogt PURINE METABOLISM IN SEVERE COMBINED IMMUNODEFICIENCY , Pages 683-685 , R.M. Goldblum, F.C. Schmalstieg, J.A. Nelson, T. Monahan, G. Mills UNILATERAL LMIF PRODUCTION IN MLC REACTION AS A MEASURE OF IMMUNOCOMPETENCE IN IMMUNODEFICIENCY DISEASES. , Pages 686-688 , A.J. Gorski, R. Gorska, S. Cunningham-Rundles, B. Dupont, J.A. Hansen, S. Pahwa, R.A. Good FURTHER CHARACTERIZATION OF NEOPLASTIC HELPER T CELLS FROM PATIENTS WITH THE SÉZARY SYNDROME , Pages 689-691 , S. Broder, E. Lawrence, M. Dunn, C. Goldman, L. Maul, T.A. Waldmann ADJUVANT PROPERTIES IN HUMAN DIALYSABLE LEUKOCYTE EXTRACTS (DLE) CONTAINING TRANSFER FACTOR , Pages 692-694 , A.O. Anderson, M.S. Ascher, L.A. Andron INTERACTION OF DEXTRAN-TRIGGERED MURINE SPLENIC CELL SUPERNATANTS AND ALLOGENEIC EFFECT FACTOR , Pages 695-697 , Belinda Yen, Jack R. Battisto T-CELL MEDIATOR INDUCTION OF NON-T CELL CYTOTOXICITY , Pages 698-700 , Peggy A. O'Neill, Bruce F. Mackler ANTI-IgD (δ) AND F(ab′) 2 ANTI-IgD ACTIVATED B CELLS ENHANCE PHA RESPONSIVENESS , Pages 701-703 , V. Kermani-Arab, G.A. Leslie, D.R. Burger KINETICS OF THE POTENTIATION OF DNA SYNTHESIS BY “LYMPHOCYTE ACTIVATING FACTOR” , Pages 704-706 , F. Kierszenbaum, B.H. Waksman STIMULATION OF HUMAN LYMPHOCYTES: ACTIVATION BY A SODIUM PERIODATE INDUCED GROWTH FACTOR , Pages 707-709 , T.M. Monahan, A.F. Frost, C.W. Abell THE EFFECT OF VARIOUS THYMIC EXTRACTS ON THE IN VITRO IMMUNE RESPONSE AGAINST SRBC AND ON MITOGEN RESPONSES AND INTRACELLULAR CAMP LEVELS OF T CELLS , Pages 710-712 , A.C.W. Swart, M.J. Blankwater, I. Betel, A.M. Kruisbeek, E.K.O. Kruithof, D.W. van Bekkum SUPPRESSION OF THE IMMUNE RESPONSE TO UV INDUCED TUMORS BY UV LIGHT , Pages 713-715 , Jerold G. Woodward, Craig W. Spellman, Raymond A. Daynes EFFECT OF CYCLOSPORIN A ON MURINE LYMPHOID CELLS , Pages 716-718 , J.F. Borel, Dorothee Wiesinger FAILURE OF LEVAMISOLE TO STIMULATE HUMORAL OR CELLULAR IMMUNITY TO SHEEP ERYTHROCYTES IN NORMAL OR T CELL DEPRIVED MICE , Pages 719-721 , Edith M. Lord, Daniel P. Stites HUMAN MONOCYTE-LYMPHOCYTE INTERACTION MEDIATED BY CONCANAVALIN A: THE EFFECT OF LEVAMISOLE , Pages 722-724 , J. Kazura, D. Guerry, W. Negendank, R.A. Cooper, A.D. Schreiber NONSPECIFIC SUPPRESSION OF THE INITIATION OF THE PRIMARY IMMUNE RESPONSE IN VITRO , Pages 725-727 , Arnold S. Rubin, Gary N. Douglas REGULATION OF AUTOIMMUNITY BY THE MODE OF PRESENTATION OF AUTOANTIGEN TO LYMPHOCYTES , Pages 728-729 , L. Steinman, I.R. Cohen, D. Teitelbaum, E. Glickman, R. Arnon SERUM FACTORS AFFECTING THE INCORPORATION OF [ 3 H]THYMIDINE BY LYMPHOCYTES STIMULATED BY ANTIGEN: INCREASED DIVERGENCE BETWEEN ANTIGEN DOSE-RESPONSE CURVES IN HEATED AND CONTROL SERUM WITH CELLS FROM RABBITS IMMUNIZED TO INCREASE THE PROPORTION OF HIGH SPECIFICITY CELLS , Pages 730-732 , D.R. Forsdyke SUPPRESSION OF THE IN VIVO HUMORAL IMMUNE RESPONSE BY A SPECIES OF NORMAN HUMAN SERUM LOW DENSITY LIPOPROTEIN , Pages 733-735 , Linda K. Curtiss, David H. DeHeer, Thomas S. Edgington THE BIOREGULATORY PROPERTIES OF SERUM LOW DENSITY LIPOPROTEIN INHIBITOR (LDL-IN) ON THE GENERATION OF KILLER T CELLS , Pages 736-738 , Thomas S. Edgington, Christopher H. Henney, Linda K. Curtiss INHIBITION OF ANTIGEN-INDUCED HUMAN LYMPHOCYTE PROLIFERATION BY DAUDI CELL LINE SUPERNATANT , Pages 739-741 , Robert T. McCalmon Jr. NATURALLY TOLERANT PIGS – REACTIVITY OF PERIPHERAL BLOOD LYMPHOCYTES (PEL) IN MIXED LYMPHOCYTE CULTURE (MLC) AND CELL MEDIATED CYTOLYSIS (CMC) , Pages 742-744 , G.P. Pawelec, B.A. Bradley, M.C.A. Puntis TWO DISTINCT HUMAN T-CELL SUBPOPULATIONS: SUPPRESSOR ACTIVITY ON PWM-INDUCED B-CELL DIFFERENTIATION IS RESTRICTED TO T CELLS BEARING Fc-IgG RECEPTORS , Pages 745-747 , L. Moretta, S.R. Webb, C.E. Grossi, P.M. Lydyard, M.D. Cooper HETEROGENEITY AMONG SUPPRESSOR T CELLS , Pages 748-750 , R.L. Whisler, J.D. Stobo THE PERSISTENCE OF IN VIVO AND IN VITRO IMMUNE RESPONSES IN THYMECTOMIZED RABBITS , Pages 751-753 , Doug Redelman, Haynes W. Sheppard Jr., Laurie Newell, Stewart Sell EVIDENCE FOR T SUPPRESSOR CELL FUNCTION IN A THYMUS INDEPENDENT MITOGENIC RESPONSE TO LIPOPOLYSACCHARIDE , Pages 754-756 , Jeffrey A. Frelinger REGULATION OF THE IMMUNE RESPONSE OF RABBIT LYMPHOCYTES BY ANTIGEN ACTIVATED SUPPRESSOR CELLS , Pages 757-759 , Doug Redelman, Haynes W. Sheppard Jr., Park E. Trefts, Deborah J. Anderson IN VITRO GENERATION OF SPECIFIC AND NON-SPECIFIC SUPPRESSION OF CELL MEDIATED CYTOTOXICITY (CMC) , Pages 760-762 , Ronald M. Ferguson, Susan M. Anderson, Richard L. Simmons RADIATION SENSITIVITY OF THE MECHANISM INDUCING NON-SPECIFIC DESENSITIZATION(ANERGY) IN GUINEA PIGS , Pages 763-765 , John M. Dwyer, Kristian Thestrup-Pedersen INHIBITION BY MEASLES VIRUS OF LYMPHOCYTE STIMULATION IN VITRO , Pages 766-768 , Kees Lucas, José Ubels-Postma SUPPRESSION OF THE HGG RESPONSE IN NORMAL MICE WITH A SPLEEN CELL LYSATE FROM TOLERANT MICE , Pages 769-771 , Thomas B. Jones, Alan M. Kaplan EVIDENCE FOR ABERRANT IMMUNOREGULATION OF NZB AUTOANTIBODYSECRETING PRECURSOR B LYMPHOCYTES , Page 772 , D.H. DeHeer FAILURE OF CONCONAVALIN A-STIMULATED LYMPHOCYTES TO SUPPRESS RESPONSIVENESS TO PHA AND ALLOGENEIC CELLS AS A MARKER OF DISORDERED IMMUNOREGULATION , Pages 773-775 , John M. Dwyer IMMUNOGLOBULIN CLASS SPECIFIC SUPPRESSOR T CELLS , Pages 776-778 , R. Michael Blaese, Andrew V. Muchmore, Irma R. Koski, Nancy J. Dooley ENHANCEMENT OF PGE 1 SENSITIVITY IN MACROPHAGES , Pages 779-781 , Diethard Gemsa, Ludwig Steggemann, Klaus Resch, Gerd Till A COMPARISON OF ALVEOLAR AND PERITONEAL MACROPHAGES AS ACCESSORY CELLS IN PHA INDUCED PROLIFERATION OF GUINEA PIG LYMPHOCYTES , Pages 782-784 , David J. Gorenberg, Ronald P. Daniele ADHERENT CELL POPULATIONS AND THE RESPONSES TO PHA, ConA, AND PPD , Pages 785-787 , M.P. Arala-Chaves, M. Horsmanheimo, A. Horsmanheimo, J. Korn, H. Hugh Fudenberg THE EFFECT OF MACROPHAGES ON TdR INCORPORATION INTO MITOGEN STIMULATED RAT LYMPHOCYTES , Pages 788-790 , Ada M. Kruisbeek, Maritavan Hees MACROPHAGE-MONOCYTE REGULATION OF THE MITOGENIC ACTIVATION OF X-RAYED, PURIFIED HUMAN T LYMPHOCYTES , Pages 791-793 , Jon R. Schmidtke, Ronald M. Ferguson MACROPHAGE MEDIATED INHIBITION OF MITOGEN-INDUCED LYMPHOCYTE BLASTOGENESIS IN MICE , Pages 794-796 , Lynn G. Baird, Alan M. Kaplan ADHERENT SUPPRESSOR CELLS IN NORMAL RAT SPLEENS , Pages 797-799 , J.R. Oehler, D.A. Campbell Jr., R.B. Herberman CHARACTERIZATION OF THE ADHERENT SPLENIC SUPPRESSOR CELLS , Pages 800-802 , A.P. Lundin III, A. Kaldany, J. Paradysz, C.B. Carpenter, T.B. Strom PRESENCE OF SPLENIC SUPPRESSOR CELLS IN ALLOGRAFT ENHANCED RATS , Pages 803-805 , A.P. Lundin III, A. Kaldany, T.B. Strom, N.L. Tilney, C.B. Carpenter RECENT ADVANCES AND QUESTIONS IN LYMPHOCYTOTOXICITY , Pages 809-816 , Gideon Berke WORKSHOP ON SUPPRESSION , Pages 819-820 , Diane M. Jacobs, Bernard W. Janicki SUBJECT INDEX , Pages 821-825