Regulation of Sleep and Circadian Rhythms (Lung Biology in Health and Disease)

Providing an up-to-date overview of the field, this state-of-the-art reference details how sleep and circadian rhythms are interconnected, revealing the impact of various disease states on, and the molecular and genetic basis for, disrupted sleep and circadian rhythmicity and their effects on physical and mental health, safety, performance, and productivity. Integrates current and rapidly advancing discoveries of sleep and circadian rhythms! Offering an integrative approach to research findings from basic science to clinical points of view, Regulation of Sleep and Circadian Rhythms discusses ·the three developmental stages of sleep in mammals ·the evolution of circadian timing ·brainstem regulation of sleep ·non-REM sleep and thalamocortical function ·cognitive correlates of behavioral states ·dysfunctional sleep ·sleep homeostasis ·neuroanatomy of circadian control ·acute effects of light ·organization of vertebrate circadian timing systems ·production, sites, and mechanisms of melatonin ·genetic aspects of pathological human sleep ·sleep alterations associated with age, disease, and psychiatric state ·and more! Complete with over 3200 references, tables, and figures, Regulation of Sleep and Circadian Rhythms is an essential resource for clinical neurologists and neurobiologists, pulmonologists, psychiatrists and behavioral scientists, endocrinologists and neuroendocrinologists, chronobiologists, sleep specialists, general medicine practitioners and internists, gerontologists, psychologists, and graduate and medical school students in these disciplines. Introduction To Sleep And Circadian Rhythm -- Ontogeny Of Sleep And Circadian Rhythms -- Neural Control Of Sleep -- Circadian And Homeostatic Control Of Wakefulness And Sleep -- Influence Of Light On Circadian Rhythmicity In Humans -- Role Of Melatonin In The Regulation Of Sleep -- Melatonin And Circadian Rhythmicity In Vertebrates: Physiological Roles And Pharmacological Effects -- Impact Of Changes In Nightlength (scotoperiod) On Human Sleep -- Cellular And Molecular Mechanisms Of Sleep -- Cellular And Molecular Mechanisms Of Circadian Rhythms In Mammals -- Molecular And Genetic Aspects Of Sleep -- Molecular Genetic Approaches To The Identity And Function Of Circadian Clock Genes -- Circadian And Sleep Control Of Hormonal Secretions -- Relationships Between Sleep And Immune Function -- Intrinsic Disruption Of Normal Sleep And Circadian Patterns -- Sleep And Circadian Rhythm Disorders In Aging And Dementia -- Effects Of Sleep And Circadian Rhythms On Performance -- Neurological Disorders Associated With Disturbed Sleep And Circadian Rhythms -- Psychiatric Disorders Associated With Disturbed Sleep And Circadian Rhythms. Edited By Fred W. Turek, Phyllis C. Zee. Includes Bibliographical References And Indexes. Details how sleep and circadian rhythms are interconnected. This book reveales the impact of various disease states on, and the molecular and genetic basis for, disrupted sleep and circadian rhythmicity and their effects on physical and mental health, safety, performance, and productivity. One of the most obvious adaptive features of living organisms on earth is the ability of almost all species to change their behavior on a daily or 24-hr basis.