Regulation of Gluconeogenesis : 9th Conference of the Gesellschaft Für Biologische Chemie

Regulation of Gluconeogenesis documents the proceedings of 9th Conference of the Gesellschaft für Biologische Chemie. This meeting was first planned as a continuation of a former Conference of the Gesellschaft für Biologische Chemie on''Stoffwechsel der isoliert perfundierten Leber''. However, the organizers of the present meeting decided that it seemed far more reasonable to restrict the subject to a special biochemical problem than to a technical procedure which had not changed very much during the last years. This volume contains 24 chapters and begins with a paper that identifies the substrates, activators, and inhibitors which may influence the rate of reaction of pyruvate carboxylase from liver. Other papers deal with topics such as purification and properties of pyruvate carboxylase from rat liver; the location of pyruvate carboxylase in mitochondria; effects of quinolinic acid on the free and total nicotinamide-adenine dinucleotides of rat liver; and effects of biguanides on gluconeogenesis in rats and guinea pigs. Content: Front Matter , Page iii Copyright , Page iv Preface , Page v , H.D. SÖLING, B. WILLMS Participants of the Meeting , Pages vi-vii Contributing Authors and Discussants , Pages viii-x Possible Control Mechanisms of Liver Pyruvate Carboxylase , Pages 1-10 , Merton F. Utter, Chien-hung Fung Purification and Properties of Pyruvate Carboxylase from Rat Liver , Pages 11-19 , C.D. Seufert, E. Herlemann, E. Albrecht, W. Seubert Comparative Studies with Pyruvate Carboxylase from Rat and Guinea Pig Liver , Pages 20-28 , J. Kleineke, H.D. Söling On the Intracellular Location of Pyruvate Carboxylase , Pages 29-49 , G. Weiss, B. Ohly, H. Brod, W. Seubert Regulation of Pyruvate Metabolism in Rat Liver Mitochondria , Pages 50-62 , P. Walter, J.W. Stucki Activities of Pyruvate Carboxylase, Phosphoenolpyruvate Carboxykinase and Pyruvate Kinase of New Zealand Obese + (NZO) Mice Livers During Different Phases of Diabetes after Starvation, Cortisol and Insulin Treatment , Pages 63-65 , B. Störmer, W. Staib The Development of Gluconeogenic Function in Rat Liver , Pages 66-91 , F.J. Ballard, Helen Philippidis Effects of Quinolinic Acid on the Free and Total Nicotinamide-Adenine Dinucleotides of Rat Liver , Pages 92-102 , D.H. Williamson, F. Mayor, Dulce Veloso On the Redox State of NAD + /NADH Systems in Guinea Pig Liver Under Different Experimental Conditions , Pages 103-113 , Berend Willms, Jochen Kleineke, Hans-Dieter Söling Gluconeogenesis and Redox State , Pages 114-126 , H.A. Krebs On the Inhibition of Gluconeogenesis by 1-β-Phenyl-Ethylbiguanide in the Perfused Guinea Pig Liver , Pages 127-139 , R. Haeckel, H. Haeckel Effects of Biguanides on Gluconeogenesis in Rats and Guinea Pigs , Pages 140-144 , H. Stork, F.H. Schmidt Regulation of Gluconeogenesis with Ethanol and Fructose by the Isolated Perfused Rat Liver , Pages 145-152 , Joachim Papenberg Fructose as a Precursor for Ketogenesis , Pages 153-159 , H.D. Söling, B. Willms Mechanism of Glucagon Activation of Gluconeogenesis , Pages 160-178 , J.H. Exton, M. Ui, S.B. Lewis, C.R. Park Dissociation of Gluconeogenic and Ketogenic Action of Glucagon in the Perfused Rat Liver , Pages 179-193 , J. Fröhlich, O. Wieland Inhibition of Hepatic Gluconeogenesis by Pent-4-enoic acid: Role of Redox State, Acetyl-CoA and ATP , Pages 194-209 , N.B. Ruderman, C.J. Toews, C. Lowy, E. Shafrir Regulation of Gluconeogenesis in Rat and Guinea Pig Liver , Pages 210-226 , H.D. Söling, B. Willms, J. Kleineke The Effect of 3′, 5′-cyclic AMP on Glucose Synthesis in Isolated Rat Kidney Tubules , Pages 226-237 , W. Guder, O. Wieland Effect of Proinsulin on the Metabolism of Alanine in Isolated Perfused Rat Livers , Pages 237-254 , K.-H. Rudorff, R. Windeck, W. Staib The Role of Pyruvate Carboxylase and P-enolpyruvate Carboxykinase in Rat Adipose Tissue , Pages 255-276 , R.W. Hanson, M.S. Patel, Lea Reshef, F.J. Ballard Stimulation of Amino Acid Metabolism and Gluconeogenesis from Amino Acids in the Liver of Fasting Rats Treated with Antilipolytic Agents , Pages 276-293 , A. Hasselblatt, U. Panten, W. Poser Transfer of Carbon and Hydrogen Across the Mitochondrial Membrane in the Control of Gluconeogenesis , Pages 293-315 , J.H. Anderson, W.J. Nicklas, B. Blank, C. Refino, J.R. Williamson, J.R. Williamson Interaction of Gluconeogenesis with Mixed Function Oxidation in Perfused Rat Liver , Pages 315-328 , Ronald G. Thurman, Roland Scholz Some Aspects of Gluconeogenesis from Pyruvate in Hemoglobinfree Perfused Rat Liver , Pages 328-347 , G. Müllhofer, O. Kuntzen