Regenerative Medicine Ii: Clinical And Preclinical Applications (advances In Biochemical Engineering/biotechnology) (pt. 2)

Organ regeneration, once unknown in adult mammals, is at the threshold of maturity as a clinical method for restoration of organ function in humans. Several laboratories around the world are engaged in the development of new tools such as stem cells and biologically active scaffolds. Others are taking fresh looks at well-known clinical problems of replacement of a large variety of organs: Bone, skin, the spinal cord, peripheral nerves, articular cartilage, the conjunctiva, heart valves and urologic organs. Still other investigators are working out the mechanistic pathways of regeneration and the theoretical implications of growing back organs in an adult. The time has come to present a collection of these efforts from leading practitioners in the field of organ regeneration. Tissue Engineering Strategies for Bone Regeneration....Pages 1-22 Simultaneous In Vivo Regeneration of Neodermis, Epidermis, and Basement Membrane....Pages 23-41 Spinal Cord Regeneration....Pages 43-66 Peripheral Nerve Regeneration....Pages 67-89 Regeneration of Articular Cartilage....Pages 91-123 Conjunctival Regeneration....Pages 125-140 Heart Valve Regeneration....Pages 141-179 Regeneration of Urologic Tissues and Organs....Pages 181-210 Each year, more than 6.3 million fractures occur in the United States [1], of which almost 1 million require hospitalization [2].