Recurrent Pregnancy Loss: Causes, Controversies and Treatment (Series In Maternal Fetal Medicine)

This book will provide an authoritative and comprehensive update on advances in the understanding and management of recurrent pregnancy loss, both with regard to the basic science and clinical applications. As many subjects are controversial, and occasionally clinical decisions are based on lack of knowledge rather than evidence, some chapters would include debates by leading experts, on the appropriate clinical management. Read more... Abstract: Recurrent Pregnancy Loss Read more... Content: Epidemiology Signaling between Embryo and Mother in Early Pregnancy Genetics of Spontaneous Abortions Debate: Should Fetal Karyotyping be performed in RPL? Debate: Should PGD be performed in RPL? Opinion: Should CVS or Amniocentesis Be Performed in RPL without Screening Does the Maternal Immune System Regulate the Embryo's Response to Teratogens? Fetal Structural Malformations: Embryoscopy Endocrinology Debate: Should Progesterone Supplements Be Used? Debate: Should hCG Supplementation Be Used? Antiphospholipid Syndrome: Pathophysiology Diagnosis of aPL-Associated Abortions Management of Antiphospholipid Syndrome in Pregnancy Defects in Coagulation Factors Leading to RPL Debate: Should Thromboprophylaxis Be Used in Hereditary Thrombophilias with RPL? Uterine Anomalies Immunobiology Debate: Should Immunotherapy Be Used in RPL? Infections Midtrimester Loss: The Role of Cerclage Midtrimester Loss and Viability Obstetric Outcomes Coping with RPL: Psychological Mechanisms Methodological Issues in Evidence-Based Evaluation of Treatment Investigation Protocol A Patient's Perspective. Exploring basic science and the clinical applications, Recurrent Pregnancy Loss: Causes, Controversies and Treatment provides an authoritative, comprehensive review of the management of recurrent pregnancy loss. Many subjects in this area are controversial, and occasionally clinical decisions are based on lack of knowledge rather than evidence. For this reason, chapters include debates by leading experts to aid the clinician in deciding on the appropriate clinical management. Chapters cover basic science, genetics, and the application of evidence based medicine as well as mid- trimester loss, late obstetric complications, and related psychological mechanisms. This book will be essential reading for specialists working in recurrent pregnancy loss clinics and associated disciplines, as well as anyone wishing to gain a comprehensive view of developments in the field This title provides an update on advances in the understanding and management of recurrent pregnancy loss, both with regard to the basic science and the clinical applications Edited By Howard J.a. Carp. Includes Bibliographical References And Index.