Receptors for Reproductive Hormones (Advances in Experimental Medicine and Biology, 36)

We are especially grateful to Dr. Philip Corfman and his colleagues of the Population and Reproduction Grants Branch of NICHD for making this Conference possible. The format of this volume follows in general the order in which the papers were presented during the Conference. The Conference was divided into four sessions, each of which was presided over by a capable and distinguished scientist. Each of these chairmen, Drs. T. H. Hamilton, G. A. Puca, R. L. Vande Wiele and H. G. Williams-Ashman provided valuable discussion and for their services we are most appreciative. The Editors are indebted to Mr. Robert Colligan for his help in organizing and in redacting the manuscripts. A special commen­ dation is also extended to Ms. Mary Jane Fowler who cheerfully and efficiently typed this entire volume. Finally, we express thanks to the individual participants of the Conference for their cooperation and prompt submission of the manuscripts and to the Plenum Press for ensuring the rapid publica­ tion of this volume. Anthony R. Means, Ph.D. Bert W. O'Malley, M. D. Front Matter....Pages i-xii The Continuing Evolution of an Estrogen-Receptor Model....Pages 1-14 Nuclear Receptor · Estrogen Complexes of Rat Uteri:....Pages 15-59 Estrogen Receptor Transformation and Nuclear RNA Synthesis....Pages 60-79 Estradiol Receptors: A New Evaluation....Pages 80-84 The Interaction of Uterine Estrogen Receptors with DNA....Pages 85-96 Estrogen Binding in the Rat and Human....Pages 97-112 Studies on the Estrogen Receptor in Breast Cancer....Pages 113-136 Studies on Androgen and Estrogen Uptake by Rat Hypothalamus....Pages 137-173 Hormone-Receptor Interactions with the Genome of Eucaryotic Target Cells....Pages 174-196 Androgens I. — A Review of Current Research on the Binding and Mechanism of Action of Androgenic Steroids, Notably 5α-Dihydrotestosterone....Pages 197-231 Androgen-Receptor Cycling in Prostate Cells....Pages 232-240 Adenyl Cyclase and the Cyclic AMP Responsive Systems in the Uterus....Pages 241-262 Affinity Labeling Steroids for Characterization of Steroid Binding Sites....Pages 263-288 Mathematics of Hormone-Receptor Interaction....Pages 289-326 Theory of Radioimmunoassays and Hormone-Receptor Interactions:....Pages 327-341 Theory of Hormone-Receptor Interaction....Pages 342-364 Autoradiographic Analysis of Gonadotropin Binding to Rat Ovarian Tissue Sections....Pages 365-378 Interactions of LH and hCG with Testicular Gonadotropin Receptors....Pages 379-418 Luteinizing Hormone Receptors in Luteinized Rat Ovaries....Pages 419-430 Specific Interaction of 3 H-FSH with Rat Testis Binding Sites....Pages 431-448 Back Matter....Pages 449-460 We are especially grateful to Dr. Philip Corfman and his colleagues of the Population and Reproduction Grants Branch of NICHD for making this Conference possible. The format of this volume follows in general the order in which the papers were presented during the Conference. The Conference was divided into four sessions, each of which was presided over by a capable and distinguished scientist. Each of these chairmen, Drs. T.H. Hamilton, G.A. Puca, R.L. Vande Wiele and H.G. Williams-Ashman provided valuable discussion and for their services we are most appreciative. The Editors are indebted to Mr. Robert Colligan for his help in organizing and in redacting the manuscripts. A special commenƯ dation is also extended to Ms. Mary Jane Fowler who cheerfully and efficiently typed this entire volume. Finally, we express thanks to the individual participants of the Conference for their cooperation and prompt submission of the manuscripts and to the Plenum Press for ensuring the rapid publicaƯ tion of this volume. Anthony R. Means, Ph. D. Bert W. O'Malley, M.D