Recent Developments in the Regulation of Kinins (Progress in Drug Research Book 69)

"This volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations - Font no determinada Front Matter....Pages i-ix Basic and Clinical Aspects of Bradykinin Receptor Antagonists....Pages 1-14 The Kallikrein–Kinin Pathways in Hypertension and Diabetes....Pages 15-36 Tissue Kallikrein-Kinin Therapy in Hypertension and Organ Damage....Pages 37-57 Renal (Tissue) Kallikrein-Kinin System in the Kidney and Novel Potential Drugs for Salt-Sensitive Hypertension....Pages 59-109 The Kallikrein-Kinin System in Diabetic Retinopathy....Pages 111-143 Genetic Manipulation and Genetic Variation of the Kallikrein-Kinin System: Impact on Cardiovascular and Renal Diseases....Pages 145-196 Back Matter....Pages 197-198 Jagdish N. Sharma, Editor. Includes Bibliographical References At The End Of Each Chapters And Index.