Recent Concepts in Sarcoma Treatment: Proceedings of the International Symposium on Sarcomas, Tarpon Springs, Florida, October 8–10, 1987 (Developments in Oncology, 55)

There have been significant advances in the treatment of sarcomas in the past several years. Further, different clini­ cal treatment programs are being advocated in different areas including surgery alone, surgery with preoperative or post­ operative chemotherapy, surgery with different radiotherapy modalities, with each investigator espousing his own treat­ ment program. On the other side, there is the question of whether these treatment programs are offering better results or whether the natural history of sarcomas has changed. The International Symposium on Sarcomas was held at Innisbrook Resort, Tarpon Springs, Florida, October 8-10, 1987. This was the first international symposium to date involving all of the disciplines treating sarcomas including pathologists, orthopaedic surgeons, general surgeons, medical oncologists, pediatric oncologists, and radiation oncol­ ogists. The Symposium brought together a number of special­ ists working in the clinical field of sarcomas for a presen­ tation of their specific treatment programs and their results. The presentations were followed by panel discussions to stimulate educational debate as to the different forms of treatment for sarcomas and to formulate some conformity in control of disease, control of spread, and ultimate function for the patient. James R. Ryan, M.D. Front Matter....Pages I-X Grading of Soft-Tissue Sarcomas....Pages 1-6 Grading of Soft Tissue Sarcomas: Experience of the EORTC Soft Tissue and Bone Sarcoma Group....Pages 7-13 Grading of Bone Tumors....Pages 14-17 The Pathological Staging of Sarcomas....Pages 18-21 The Diagnosis of Soft Tissue Tumors. The Göteborg Experience....Pages 22-26 The Role of the Pathologist in the Treatment of Osteosarcoma....Pages 27-29 Musculoskeletal Tumor Staging — 1987 Update....Pages 30-39 Electron Microscopy of Sarcomas....Pages 40-47 Immunohistochemistry in Sarcomas....Pages 48-58 Cellular Composition of Sarcomas....Pages 59-64 Preoperative Evaluation of Extremity Sarcomas....Pages 65-68 Open Biopsy of Sarcomas....Pages 69-75 Fine Needle Aspiration Cytology in Diagnosis and Management of Bone and Soft Tissue Tumors....Pages 76-80 The Role of Frozen Sections in the Diagnosis and Management of Bone and Soft-Tissue Tumors....Pages 81-88 Surgical Management of Soft Tissue Sarcomas....Pages 89-93 Limited Surgery and External Irradiation in Soft Tissue Sarcomas....Pages 94-103 Brachytherapy and Limb-Sparing Resection in the Management of Soft Tissue Sarcoma....Pages 104-114 Neoadjuvant Chemotherapy, Radiation, and Limited Surgery for High Grade Soft Tissue Sarcoma of the Extremity....Pages 115-122 National Cancer Institute Experience in the Management of High-Grade Extremity Soft Tissue Sarcomas....Pages 123-129 Adjuvant Therapy for Soft Tissue Sarcomas....Pages 130-135 Pediatric Experience in Rhabdomyosarcoma....Pages 136-143 Results of a Randomized Trial for the Treatment of Localized Soft Tissue Tumors (STS) of the Extremities in Adult Patients....Pages 144-148 Soft Tissue Sarcomas — Japanese Experience....Pages 149-155 European Experience of Adjuvant Chemotherapy for Soft Tissue Sarcoma: Interim Report of a Randomized Trial of Cyvadic Versus Control....Pages 156-163 Results of the German Soft-Tissue Sarcoma Study....Pages 164-167 A Pilot Study of Adriamycin, Dacarbazine and Ifosfamide in Advanced Adult Soft Tissue Sarcomas....Pages 168-173 Chemotherapy of Advanced Soft Tissue Sarcomas....Pages 174-182 Chemotherapy in Advanced Soft Tissue Sarcoma — The EORTC Experience....Pages 183-190 Prognostic Indicators for Soft Tissue Sarcoma Patients with Pulmonary Metastases....Pages 191-196 Pulmonary Resection in Sarcoma Metastases....Pages 197-200 Treatment of Gynecologic Sarcomas....Pages 201-209 The Current Role of Surgical Therapy in Ewing’s Sarcoma....Pages 210-217 The Role of Chemotherapy in the Management of Ewing’s Sarcoma....Pages 218-223 The Role of Radiation Therapy in the Management of Ewing’s Sarcoma....Pages 224-230 The German Pediatric Oncology (GPO) Cooperative Study on Ewing’s Sarcoma....Pages 231-234 Natural History of Osteosarcoma—Has it Changed?....Pages 235-238 Limb Salvage for Osteosarcoma....Pages 239-240 Pelvic Resection in Bone Sarcomas....Pages 241-244 En Bloc Surgery for Osteogenic Sarcoma: Analysis and Review of 180 Cases....Pages 245-249 The Use of Bone Allograft Transplants in the Management of Bone Tumors....Pages 250-260 Surgical Alternatives to Standard Endoprosthetic Replacement and Allograft Reconstruction for Malignant Tumors of the Musculoskeletal System....Pages 261-268 Arterial Infusion in the Treatment of Osteosarcoma....Pages 269-274 Intra-Arterial Cis-Diamminedichloroplatinum-II in Pediatric Osteosarcoma: Relationship of Effect on Primary Tumor to Survival....Pages 275-282 Adjuvant Chemotherapy in the Treatment of Osteosarcoma: Results of the Multi-Institutional Osteosarcoma Study....Pages 283-290 Neoadjuvant Chemotherapy for Osteosarcoma — Results of a Prospective Study....Pages 291-295 The German Pediatric Oncology (GPO) Cooperative Study on Osteosarcoma....Pages 296-300 The Experience of T10 Protocol in the Pediatric Department of the Gustave Roussy Institute....Pages 301-305 Adjuvant Treatment with Radiotherapy to the Lungs and/or Chemotherapy for Osteosarcoma of the Limbs....Pages 306-312 Osteosarcoma — Japanese Experience....Pages 313-319 New Therapeutic Directions in Sarcomas: Biologic and Cytotoxic Modalities....Pages 320-327