Realizing the Promise of Precision Medicine : The Role of Patient Data, Mobile Technology, and Consumer Engagement

__Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement__ explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases. * Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine * Includes sidebars with more details on specific topics for a complementary, deeper understanding of the main text * Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients Front Cover REALIZING THE PROMISE OF PRECISION MEDICINE REALIZING THE PROMISE OF PRECISION MEDICINE: The Role of Patient Data, Mobile Technology, and Consumer Engagement Copyright DEDICATION CONTENTS ABOUT THE AUTHORS PROLOGUE: NAKED EMPERORS AND SUPERCOMPUTERS REFERENCES One - Population Medicine Versus Personalized Medicine CURE VERSUS MANAGEMENT THE LIMITATIONS OF POPULATION-BASED MEDICINE APPLYING THE PRECISION MEDICINE MODEL HOW DOES THE PRECISION MEDICINE INITIATIVE FIT INTO THE EQUATION? PUTTING THE PRECISION MEDICINE MODELTO WORK NOW UNDERSTANDING THE INTERLOCKING CONTRIBUTORS TO DISEASE THE BIOLOGICAL BASIS FOR PERSONALIZED MEDICINE THE ROLE OF THE MICROBIOME DIGITAL TOOLS THAT ENABLE PRECISION MEDICINE REFERENCES Two - Precision Medicine Initiatives and Programs THE US PRECISION MEDICINE INITIATIVE MANAGING DATA EXECUTING THE US PRECISION MEDICINE INITIATIVE WHAT WILL THE PRECISION MEDICINE INITIATIVE REVEAL? THE AGE OF BIOMARKERS IS UPON US PATIENT ENGAGEMENT: A CRITICAL COMPONENTOF PRECISION MEDICINE THE VALUE OF PRECISION MEDICINE INITIATIVEDATA REACHES BEYOND THE US PRECISION MEDICINE INITIATIVE PROJECT THE ROLE OF ELECTRONIC HEALTH RECORD DATA PRECISION MEDICINE AT HARVARD PRECISION MEDICINE AT COLUMBIA UNIVERSITY JOHNS HOPKINS APPROACH TO INDIVIDUALIZED CARE MAYO CLINIC CENTER FOR INDIVIDUALIZED MEDICINE STANFORD UNIVERSITY EMPHASIZE SPATIENT ENGAGEMENT REFERENCES Three - The Role of Genomics GENOMIC BASICS PUTTING GENOMICS TO USE IN PRECISION MEDICINE ENTERING THE ERA OF PRECISION ONCOLOGY IS CANCER A GENETIC DISEASE? THE VALUE OF PHARMACOGENOMICS THE EMERGING SCIENCE OF NUTRITIONAL GENOMICS REFERENCES Four - Small Data, Big Data, and Data Analytics UNDERSTANDING THE LANGUAGE OF DATA ANALYTICS ALGORITHMS AND MACHINE LEARNING PUTTING DATA ANALYTICS TO THE TEST THE ROLE OF BIG DATA IN HYPOTHESIS TESTING RECONCILING BIG DATA AND RANDOMIZED CONTROLLED TRIALS REFERENCES Five - How Mobile Technology and EHRs Can Personalize Healthcare ACCESSING PATIENTS’ “OTHER” DATA THE ROLE OF MOBILE TECHNOLOGY IN DIABETES CONTROL THE ROLE OF MOBILE TECHNOLOGY IN OTHER DISEASES REMOTE PATIENT MONITORING WHERE DO EHRs FIT IN? CLINICAL DECISION SUPPORT SYSTEMS STAR TREK–LIKE DECISION-MAKING TOOLS Six - i2b2, SHRINE, Clinical Query, and Other Research Tools TAKING INFORMATICS FOR INTEGRATING BIOLOGY AND THE BEDSIDE INTO NEW TERRITORY SHARED HEALTH RESEARCH INFORMATICS NETWORK EXTENDS THE INFORMATICS FOR INTEGRATING BIOLOGY AND THE BEDSIDE REACH THE IMPACT OF SHARED HEALTH RESEARCH INFORMATION NETWORK ON SCIENTIFIC RESEARCH BETH ISRAEL DEACONESS MEDICINE AND CLINICAL QUERY 2 MOVING TOWARD A NATIONAL NETWORK PATIENT-CENTERED OUTCOMES RESEARCH INITIATIVES REFERENCES Seven - Barriers and Limitations DOES PRECISION MEDICINE COST TOO MUCH? FILLING THE GENOMICS INFORMATION GAP ADDRESSING THE WORKLOAD ISSUE IS THERE ADEQUATE SCIENTIFIC EVIDENCE? ADDITIONAL BARRIERS TO SURMOUNT REFERENCES Eight - Interoperability and Personalized Patient Care DEFINING THE BASICS AND FOLLOWING A ROADMAP WHAT DRIVES INTEROPERABILITY? POLICY AND TECHNICAL COMPONENTS LEARNING FROM OUR MISTAKES ADDRESSING SECURITY CONCERNS UNDERSTANDING THE STANDARDS THAT FACILITATE INTEROPERABILITY WHAT OUTCOMES CAN BE EXPECTED? REFERENCES Nine - Privacy and Security KEEPING PATIENT DATA SAFE AT THE GRASSROOTS LEVEL INSECURITY IS EXPENSIVE ADDITIONAL HEALTH INSURANCE PORTABILITY AND ACCOUNTABILITY ACT VIOLATION EXPENSES CALCULATING THE COST OF SECURITY HOW DO THE HIPAA REGULATIONS FIT IN? TAKING THE NECESSARY PREVENTIVE MEASURES PASSWORDS, POLICIES, AND PROCEDURES TECHNOLOGICAL SOLUTIONS APPLYING SECURITY PRINCIPLES TO PRECISION MEDICINE INITIATIVE A CASE SCENARIO REQUIRING SECURITY PROTOCOLS REFERENCES Ten - Patient and Consumer Engagement ENGAGING RESPONSIBLE PATIENTS THE RETURN ON INVESTMENT PATIENT PORTALS ARE NOT ENOUGH SHARED DECISION MAKING PATIENT-GENERATED DATA AND MOBILE ENGAGEMENT FINAL THOUGHTS ON THE PROMISE OF PRECISION/PERSONALIZED MEDICINE REFERENCES INDEX A B C D E F G H I J L M N O P R S T U V W Back Cover "Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases.Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine includes sidebars with more details on specific topics for a complementary, deeper understanding of text. Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients"-- Provided by publisher