Radiotherapy for Non-Malignant Disorders (Medical Radiology / Radiation Oncology) (Medical Radiology / Radiation Oncology)

This volume discusses the general background, radiobiology, radiophysics and clinical applications of radiation therapy in the treatment of non-malignant diseases. Within 39 chapters, it documents the rationale and indications for the use of state-of-the-art radiotherapy for various non-malignant disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and the vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases. With the assistance of many tables and colored figures, the extensive data from clinical studies are presented in a well-structured and informative way. Each chapter concludes with a list of key points, allowing the reader to quickly comprehend the main facts. Since this approach offers an interdisciplinary perspective, this book will be of interest not only to radiotherapists but also to many other practitioners and medical specialists, for example orthopedists, surgeons, and ophthalmologists. General Background -- 1. Radiobiological Principles / K.-r. Trott, F.-h. Kamprad And G. Hildebrandt -- 2. Side Effects And Long-term Risks From Radiotherapy Of Benign Diseases / K.-r. Trott And F.-h. Kamprad -- 3. Risk Assessment And Carcinogenesis Modelling / J. J. Broerse, J. T. M. Jansen And J. Zoetelief -- 4. Radiophysical Principles / U. Wolf And T. Wiezorek -- 5. Clinical Principles / M. H. Seegenschmiedt And U. Schafer -- 6. Irradiation Of Non-malignant Diseases: A Survey / J. W. H. Leer, P. Van Houtte And J. Davelaar -- 7. Patterns Of Care Study For Non-malignant Diseases In Germany / M. H. Seegenschmiedt And O. Micke / The German Cooperative Group On Benign Diseases (gcg-bd) -- Skin And Soft Tissue Disorders -- 8. Tumors, Hyperplasia, Dermatoses / R. G. Panizzon, R. O. Mirimanoff And M. H. Seegenschmiedt -- 9. Morbus Dupuytren / Morbus Ledderhose / M. H. Seegenschmiedt -- 10. Peyronie's Disease / L. Incrocci -- 11. Keloids And Hypertrophic Scars / B. Guix, A. Andres, P. Salort, J. I. Tello, I. Henriquez, J. A. Lejarcegui And M. H. Seegenschmiedt -- 12. Aggressive Fibromatosis/desmoid Tumors / O. Micke, H. T. Eich, F. Bruns, J. Heide, G. Gosheger And M. H. Seegenschmiedt -- Bone And Joint Disorders -- 13. Orthopaedic Examination, Tests And Clinical Scores / O. Micke And M. H. Seegenschmiedt -- 14. Rotator Cuff Syndrome (rcs) / B. Adamietz -- 15. Humeral Epicondylopathia (hep), Lateral And Medial Humeral Epicondylitis / M. H. Seegenschmiedt, Felicitas Guntrum And H. Krahl -- 16. Calcaneodynia: Plantar And Dorsal Heel Spur/heel Spur Syndrome / O. Micke, A. Ernst-stecken, R. Mucke And M. H. Seegenschmiedt -- 17. Degenerative Joint Disease/activated Osteoarthrosis Deformans: Hip/knee/shoulder/other Joints / G. Hildebrandt And F.-h. Kamprad -- 18. Heterotopic Ossifications; General Survey For All Sites / M. H. Seegenschmiedt, O. Micke And R. Heyd -- 19. Heterotopic Ossification Prophylaxis -- The Hip / O. Kolbl, W. E. Alberti And M. H. Seegenschmiedt -- 20. Heterotopic Ossifications After Head And Spinal Cord Injuries (hsci) / M.-l. Sautter-bihl, P. Lukas, E. Liebermeister, D. Maier And A. Nanassy -- 21. Pigmented Villonodular Synovitis (pvns) / R. Oppenkowski And M. H. Seegenschmiedt -- 22. Langerhans Cell Histiocytosis (lch) / T. Olschewski, O. Micke And M. H. Seegenschmiedt -- 23. Vertebral Hemangiomas (svh) / R. Heyd And M. H. Seegenschmiedt -- 24. Aneurysmal Bone Cyst (abc) / R. Heyd And M. H. Seegenschmiedt -- Vascular Disorders -- 25. Giant Hemangioma/kasabach-merritt Syndrome / P. Schueller, S. Hesselmann And O. Micke -- Eye Disorders -- 26. Graves' Orbitopathy / S. Staar, H. T. Eich And M. H. Seegenschmiedt -- 27. Pseudotumor Orbitae / M. Notter And K. M. Greven -- 28. Pterygium / R. H. Greiner, B. Pajic And J. Kutzner -- 29. Hemangiomas And Vascular Tumors Of The Eye / M. Murty, J. E. Freire, C. L. Shields, J. A. Shields, A. Mashayekhi And L. W. Brady -- Local And Systemic Inflammatory Disorders -- 30. Inflammatory Disorders: Furunculitis, Hidradenitis, Panaritium And Paronychia / D. Frohlich, D. Baaske And M. Glatzel -- 31. Lymphocutaneous Fistulas And Lymphoceles / B. Neu And W. Haase -- 32. Local Rheumatoid Arthritis And Radiation Synevectomy / G. M. Kacl And G. Stucki -- Head And Neck -- 33. Non-malignant Disorders Of The Head Region / R. Oppenkowski And M. H. Seegenschmiedt -- Cns And Brain -- 34. Arterio-venous Malformation / M. W. Gross And R. Engenhart-cabillic -- 35. Meningeoma / S. Milker-zabel And J. Debus -- 36. Vestibular Schwannoma (acoustic Neuroma) / A.-l. Grosu, E. Oestreicher, C. Fauser, C. Lumenta, W. J. Arnold And M. Molls -- 37. Pituitary Adenoma / D. Zierhut -- 38. Trigeminal Neuralgia / M. Attassi, M. H. Seegenschmiedt And M. Korner -- 39. Radiosurgical Treatment Options For Epileptic Disorders / H. G. Wieser -- 40. Where There Is No Evidence: Registry For Rare Benign Diseases / O. Micke, A. Koehler And M. H. Seegenschmiedt. M.h. Seegenschmiedt ... [et Al.] (eds.) ; With Contributions By B. Adamietz ... [et Al.] ; Foreword By L.w. Brady ... [et Al.]. Includes Bibliographical References And Index. Front Matter....Pages I-XV Front Matter....Pages 1-1 Radiobiological Principles....Pages 3-27 Side Effects and Long-Term Risks from Radiotherapy of Non-malignant Diseases....Pages 29-43 Risk Assessment and Carcinogenesis Modelling....Pages 45-58 Radiophysical Principles....Pages 59-87 Clinical Principles....Pages 89-119 Irradiation of Non-malignant Diseases: An International Survey....Pages 121-132 Patterns-of-Care Study for Non-malignant Diseases in Germany....Pages 133-143 Front Matter....Pages 145-145 Non-malignant Skin Disorders: Tumors, Hyperplasia, Dermatoses....Pages 147-159 Morbus Dupuytren/Morbus Ledderhose....Pages 161-191 Pronie’s Disease....Pages 193-207 Keloids and Hypertrophie Scars....Pages 209-224 Aggressive Fibromatosis/Desmoid Tumors....Pages 225-234 Front Matter....Pages 235-235 Orthopaedic Examination, Tests and Clinical Scores....Pages 237-259 Rotator Cuff Syndrome (RCS)....Pages 261-279 Humeral Epicondylopathia (HEP), Lateral and Medial Humeral Epicondylitis....Pages 281-294 Calcaneodynia: Plantar and Dorsal Heel Spur/Heel Spur Syndrome....Pages 295-315 Degenerative Joint Disease Activated Osteoarthrosis Deformans: Hip, Knee, Shoulder and Other Joints....Pages 317-332 Heterotopic Ossifications: General Survey for All Sites....Pages 333-355 Heterotopic Ossification Prophylaxis - The Hip....Pages 357-371 Heterotopic Ossifications after Head and Spinal Cord Injuries (HSCI)....Pages 373-381 Front Matter....Pages 235-235 Pigmented Villonodular Synovitis (PVNS)....Pages 383-395 Langerhans′ Cell Histiocytosis (LCH)....Pages 397-423 Vertebral Hemangioma (VH)....Pages 425-440 Aneurysmal Bone Cyst (ABC)....Pages 441-455 Front Matter....Pages 457-458 Giant Hemangioma/Kasabach-Merritt Syndrome....Pages 459-466 Front Matter....Pages 467-467 Graves’ Orbitopathy....Pages 469-486 Pseudotumor Orbitae....Pages 487-500 Pterygium....Pages 501-512 Hemangiomas and Vascular Tumors of the Eye....Pages 513-520 Front Matter....Pages 521-521 Inflammatory Disorders: Furunculitis, Hidradenitis, Panaritium and Paronychia....Pages 523-536 Lymphocutaneous Fistulas and Lymphoceles....Pages 537-546 Local Rheumatoid Arthritis and Radiation Synovectomy....Pages 547-561 Front Matter....Pages 563-563 Non-Malignant Disorders of the Head Region....Pages 563-579 Front Matter....Pages 581-581 Arterio-Venous Malformations....Pages 583-607 Meningioma....Pages 609-628 Vestibular Schwannoma (Acoustic Neuroma)....Pages 629-652 Pituitary Adenoma....Pages 653-663 Trigeminal Neuralgia....Pages 665-677 Radiosurgical Treatment Options for Epileptic Disorders....Pages 679-700 Where There is No Evidence: Registry for Rare Benign Diseases....Pages 701-723 Back Matter....Pages 725-747 Non-malignant, or'benign', diseases can be successfully treated using ionizing rad- tion technologies. It was first proposed in 1898 by Sokoloff, who reported the analgesic effects of radiotherapy for painful rheumatoid arthritis. Since then, the use of these techniques for painful muscle-skeletal diseases has gained acceptance particularly in Europe but is still carried out actively in the United States. Non-malignant diseases that are amenable to radiotherapy can be classified as inflammatory, degenerative, hype- roliferative, functional, or other disorders. However, the topographic and morphologic considerations are more relevant. Even though radiation therapy for'benign'diseases has not been pursued actively since the 1950s, more recent interest has dictated that it can be a very effective treatment modality. The use of radiotherapy can be justified for invasive and aggressive growth such as that seen with desmoids, for cosmetic d- figurations and functional loss as seen with keloids or endocrine orbitopathy, or for life-threatening complications such as hepatic hemangiomas or juvenile angiofibromas that occur in children or adolescents. Many of the non-malignant diseases can have a major and lasting effect on quality of life by causing pain or other serious symptoms, particularly when other methods of treatment are unavailable, have failed, or may induce more side effects. It is not generally the first choice of therapy in these non-malignant diseases, but it is acceptable as defined. The book edited by Seegenschmiedt et al. This Volume Discusses The Background And Various Clinical Applications Of Radiation Therapy In The Treatment Of Non-malignant Diseases. It Documents The Radiobiological And Physical Principles Of Treatment And The Rationale Underlying The Use Of Radiotherapy For Various Disorders Of The Cns, Head And Neck, Eye, Skin And Soft Tissues, Bone And Joints, And Vascular System. In So Doing, It Draws Attention To And Elucidates The Scope For Application Of Radiotherapy Beyond The Treatment Of Malignancies. Both The Risks And The Benefits Of Such Treatment Are Fully Considered, The Former Ranging From Minor Clinical Problems To Life-threatening Diseases.