Radioactive Isotopes In Clinical Medicine And Research Xxiii (advances In Pharmacological Sciences)

Radioactive Isotopes in Clinical Medicine and Research XXIII presents an update in the latest clinical research in nuclear medicine. It provides in-depth information on all areas of nuclear medicine. The chapters of this volume have been grouped into the following sections: Neurology / Psychiatry, Therapy, Radiopharmacology, Endocrinology / Thyroid, Oncology / Haematology, Clinical PET, Cardiology, Varia, Physics / Radiation Protection, World Wide Web / WWW demo. Special attention is paid to the virtual media for teaching, training, communication, quality control etc. Primarily intended for specialists in the nuclear medicine, this volume will also be of considerable interest to clinicians using diagnostic and therapeutic nuclear medicine procedures, including cardiologists, haematologists, neurologists, nephrologists, oncologists, pharmacologists, and psychiatrists. Front Matter....Pages I-XXIX Front Matter....Pages 1-1 The Challenge of the 21 st Century....Pages 3-15 Front Matter....Pages 17-17 First Evaluation in Humans of [ 123 I]PE2I: A Selective Radioligand for Visualization of the Striatal Dopamine Transporter Density....Pages 19-23 Comparison of Iodine-123 Labelled Nor-β-CIT and β-CIT as Potential Radioligands for Serotonin Transporter Imaging....Pages 25-30 Brain Serotonin and Dopamine Transporters in Depressive Children....Pages 31-36 Prognostic Potential of Tc-99m-ECD-SPET Within 6 Hours after Onset of Stroke Symptoms....Pages 37-42 Brain Perfusion in Patients with Severe Sleep Apnea Syndrome (SAS) before and after n-CPAP-Therapy....Pages 43-47 Front Matter....Pages 49-49 Radioimmunotherapy of Colorectal Cancer in Small Volume Disease: Preclinical Evaluation in Comparison to Equitoxic Chemotherapy and Preliminary Results of an Ongoing Phase-I/II Clinical Trial....Pages 51-57 Radioimmunotherapy of Glioblastoma by Using 1-131 and Y-90 Labeled Antitenascin Monoclonal Antibodies....Pages 59-63 I-131-Lipiodol Therapy in Liver Neoplasms....Pages 65-70 Individualized Dose Estimation for Sr-89 with the Use of Diagnostic Tc-99m MDP Bone Scintigraphy....Pages 71-77 Rhenium-186-HEDP and Strontium-89-Chloride in Treatment of Metastatic Bone Pain....Pages 79-84 The Development of Chromatographic 188 W/ 188 Re Generators for Therapy....Pages 85-90 Front Matter....Pages 91-91 Evaluation of mRNA Targeting by Labeled Oligonucleotides for Tumor-Diagnosis....Pages 93-98 Synthesis and Evaluation of [ 123 I]Iodoaminoglutethimide, a Ligand for Visualization of the Aromatase Enzyme by Spect....Pages 99-103 Comparative Analysis of Kinetic Models to Study Glucose Metabolism of the Brain....Pages 105-110 Bone Scintigraphy and Palliative Therapy with Multibone Kit....Pages 111-116 Pharmacoscintigraphic Study of Localization in the G.I. Tract of Controlled Release Tablets Using 153 Sm as Marker....Pages 117-122 Front Matter....Pages 123-123 On The Use of Routine Preoperative Scintigraphy in Thyroid Carcinoma Patients....Pages 125-130 The Value of Hmpao Spect Scanning in Patients With Congenital Hypothyreosis....Pages 131-136 Advanced Stage Thyroid Cancer — Treatment with Isotretinoin....Pages 137-141 Front Matter....Pages 123-123 Is Spect-Technique Necessary for Preoperative Diagnostis of Parathyroid Adenoma ?....Pages 143-148 Front Matter....Pages 149-149 Comparison of Interlesionally and Systemically Administered Radiolabelled Monoclonal Antibodies in Implanted Tumours....Pages 151-157 Comparison of MRI and Somatostatin Receptor Scintigraphy (SRS) in Postsurgical Follow-Up of Meningioma....Pages 159-164 Comparison of Contrast Enhanced MRI, Tc-99m Hydroxy-Methylene Diphosphonate and Tc-99m Tetrofosmin Scinti-Mammography in Patients with Suspicious Breast Lesions....Pages 165-170 Neoadjuvant Treatment of Patients with Breast Cancer under Surveillance of 99m-Tc-Tetrofosmin Scintigraphy....Pages 171-174 99m Tc-Furifosmin Uptake by Melanoma Cells....Pages 175-178 Lymphoscintigraphy in Tumors of the Head and Neck Using a Double Tracer Technique....Pages 179-184 Front Matter....Pages 185-185 Clinical Application of 18 FDG-PET in the Assessment of Head and Neck Tumors....Pages 187-192 The Role of FDF-PET and MIBI Investigations in the Restaging of Treated Patients with Malignant Lymphomas....Pages 193-198 Assessment of Pulmonary Nodules and Colorectal Cancer Recurrences by FDG Scan on an «Ordinary» Coincidence Gamma Camera (CDET)....Pages 199-206 Clinical Utility of 18 FDG-PET with Molecular Coincidence Detection (MCD) and a Modified Spect-Camera....Pages 209-214 Deoxyglucose Uptake by Apoptosing and Proliferating Colonic Tumour Cells....Pages 215-220 Front Matter....Pages 221-221 Relation between Viability, Improvement of Lvef and Heart Failure Symptoms after Revascularization....Pages 223-227 Attenuation Corrected Tl-201 Spect Using a Gd-153 Moving Line Source: Clinical Value and the Impact of Attenuation Correction on the Extent and Severity of Perfusion Abnormalities....Pages 229-234 Correlation of EBCT and TL-201-SPECT Scintigraphy in Patients with Coronary Heart Disease....Pages 235-240 Influence of Right Ventricular Stimulation Site on Left Ventricular Function in Atrial Synchronous Pacing....Pages 241-246 Front Matter....Pages 247-247 153 SM-EDTMP for Pain Relief in Malignant and Benign Bone and Joint Diseases....Pages 249-254 TC-99M-Tetrofosmin Spect Scintigraphy in the Post-Operative Followup of Microvascular Anastomosed Flaps in Facial Reconstruction....Pages 255-259 Long-Term Follow-Up Study of Gastric Emptying and Helicobacter Pylori Eradication among Patients with Functional Dyspepsia....Pages 259-263 The Value of Renal Scintigraphy under Controlled Diuresis in Children with Hydronephrosis....Pages 265-270 Front Matter....Pages 247-247 Assessment of Brain Perfusion by ECD-Tc99m SPET IN RETT Syndrome....Pages 271-276 Detection of Inflammatory Bowel Diseases in Children with 99m Tc Antigranulocyte Mab (BW 250/183) Scintigraphy....Pages 277-281 Front Matter....Pages 283-283 Attenuation Correction in PET Using CS-137 Singles Transmission and Iterative Reconstruction....Pages 285-290 Optimization of Acquisition Protocols Based on 18F-FDG Phantom Studies Using a Dual Head SPECT Camera in Coincidence Mode....Pages 291-296 Radiation Protection in I-131-Lipiodol Therapy in Liver Neoplasms....Pages 297-302 Radiation Exposure Deriving from Patients Treated with 165 Dy-Ferric Hydroxide....Pages 303-306 Reconstruction Of SPECT Data Using an Artificial Neural Network....Pages 307-312 Front Matter....Pages 313-313 The Use of Internet as a Mode of Delivery for Nuclear Medicine Postgraduate Education....Pages 315-320 Two Years Experience with an Exclusively Internet-Based Virtual Lecture for Medical Students and Postgraduates....Pages 321-325 Tele Nuclear Medicine on the World Wide Web....Pages 327-331 A Java-Enhanced Nuclear Medicine Teaching File....Pages 333-338 Emerald — European Medical Radiation Learning Development — for Vocational Training and Interactive Learning on World Wide Web — Nuclear Medicine Training Module....Pages 339-344 Java-Based Remote Viewing Station for Nuclear Medicine Images....Pages 345-349 Front Matter....Pages 351-351 Preoperative Determination of Stroke Risk with ECD SPECT before Therapeutic Carotid Artery Occlusion....Pages 353-356 Asymmetry of the Dopaminergic System in Schizophrenic Patients....Pages 357-360 Blood Flow Changes in Cerebral and Cerebellum Cortex in Obsessive-Compulsive Disorder Patients Evaluated with ECD-Tc99m SPET....Pages 361-364 99m Tc-HMPAO SPECT in Borderline Conditions Related to the Aging Brain....Pages 365-369 Quantitative Brain Perfusion Analysis in Hypertension During Rest and Exercise Technetium-99M-HMPAO Single-Photon Emission Computed Tomography....Pages 371-374 Long-Term Side Effects after High Dose Radioiodine Therapy in Thyroid Carcinoma Patients....Pages 375-378 Intraarterial I-131-MIBG Treatment — Clinical and Dosimetric Results....Pages 379-382 Front Matter....Pages 351-351 Development of 166 Ho-Ho, Fe-Hydroxide (HFH) and 166 Ho-Hydroxyapatite (HA) for Radioembolization Therapy of Liver Malignancies....Pages 383-386 Possible Use of 11 C-Labeled 8-(3-Chlorostyryl) Caffeine (CSC) Mapping A 2A Adenosine Receptors in the CNS and Myocardium....Pages 387-390 In-Vitro Studies on the Usefulness of 99m TC-Tetrofosmin for Sarcoma Detection....Pages 391-394 The Effect of Metabolic Degradation on Radiotracer Design....Pages 395-401 Investigation of Rhenium Complex Formation for Development of Boneseeking Kit for 18 8-W/188-RE Generator....Pages 403-408 199 TL-Diethyldithiocarbamate — SPECT in Diagnosis of Brachiocephalic Arteries Atherosclerosis....Pages 409-412 Vincristine Effect on the Distribution of Radiopharmaceuticals in Mice....Pages 413-416 Front Matter....Pages 417-417 Assessment of Left Ventricular Ejection Fraction Using Radionuclide Ventriculography in Patients with Acromegaly....Pages 419-422 Technetium-99m-Pertechnetate Scintigraphy in Small Thyroid Nodules....Pages 423-426 The Imaging of Thyroid Tumors: MRI Vs. Radionuclide Scintigraphy and Ultrasound....Pages 427-431 Pulmonary Tuberculosis and Its Therapy’S Effect on Thyroid Function. A Short-Term Prospective Study....Pages 433-436 Serum Total T3-, T4-and TSH-Concentrations in Vietnamese Newborn Babies Living in Endemic Nongoitrous (ENR) and in Endemic Goitrous (EGR) Regions During the First Seven Days of Life....Pages 437-441 High Activity Radioiodine Therapy for Advanced Differentiated Thyroid Carcinoma: Efficacy and Morbidity....Pages 443-449 Posttherapeutic Care of Patients with Medullary Thyroid Carcinoma — Diagnostic Value of In-Vitro-Parameters and Imaging....Pages 451-454 Improved Negative Predictive Value of Mammoscintigraphy in Patients with Breast Cancer by Means of a “Malignancy Index”....Pages 455-458 Quantitative Tc-99m Tetrofosmin Scintigraphy in the Differentiation of Malignant from Benign Breast Masses....Pages 459-462 The Relationship between Proliferation and Deoxyglucose Uptake by Breast Tumour Cells....Pages 463-466 Potential Role of Whole-Body 18 FDG-PET in the Routine Staging of Malignant Melanoma....Pages 467-470 The Possible Place of FDG-PET Investigations in the Differential Diagnosis of Focal Pancreatic Lesions....Pages 471-474 FDG PET in the Follow-Up of Patients with Differentiated Thyroid Cancer....Pages 475-478 Front Matter....Pages 417-417 Aprotinin 99mTc Myocardial Scan: Risk Stratification of Cardiac Events in Patients with Al/Attr Amyloidosis....Pages 479-482 Disturbed Myocardial Energy Metabolism in Patients with Nontransmural Chronic Myocardial Infarction....Pages 483-486 Quantitative, Multivariate Analysis — Based Assessment of MIBI Planar Heart Perfusion Studies....Pages 487-490 Front Matter....Pages 491-491 Detection of Fistulae in Crohn’s Patients with Immunoscintigraphy (IS)....Pages 493-496 Immunoradiometric Assay of Total PSA, Free PSA and PSA Ratio Calculation in Prostatic Cancer (PCa) Diagnosis....Pages 497-500 3-D-Imaging and Volume Mathematics Versus Common Static Imaging in Combined Inhalation / Perfusion Lung Scintigraphy....Pages 501-504 Investigation of Plazminogen Activator Effects on Progressive Ischemia into the Tissue Adjacent the Burn Injury By Tc-99m MIBI Scintigraphy and Autoradiography in an Experimental Local Burn Model....Pages 505-509 Improvement in Spect Imaging and Reduction of the Absorbed Dose Using an Additional Compton Energy Window for 18 FDG....Pages 511-514 Usable Countrates for a Commercially Available Dual-Head-PET System....Pages 515-518 Internal Exposure to Relatives of Radioiodine Therapy Patients from 1-131 Inhalation at Home....Pages 519-522 The Usage Of Gated SPECT in Lung Scintigraphy Phantom Studies and Clinical Results....Pages 523-526 The Department of Nuclear Medicine, Szeged, on the Internet....Pages 527-530 Nuclear Medicine Image Data Easy Transfer Via E-Mail....Pages 531-534 Talk to Your Patients Vi@ Internet! Patient Information in a Community Network....Pages 535-538 Front Matter....Pages 539-539 Factors Influencing Myocardial Uptake of MIBG In-Vitro....Pages 541-544 Binding Studies with Oxidized and Glycated 125 I-LDL to Detect Macrophage Scavenger-and Age-Receptors in Atherosclerotic Lesions....Pages 545-549 Auger and Conversion Electron Therapy with In-111 Pentetreotide in Hepatocellural Carcinoma....Pages 551-554 Back Matter....Pages 555-561