Radiation Risk Estimates in Normal and Emergency Situations (NATO Science for Peace and Security Series / NATO Science for Peace and Security Series B: Physics and Biophysics)

Cover......Page 1 NATO Security through Science Series......Page 3 Radiation Risk Estimates in Normal and Emergency Situations......Page 4 ISBN-13 9781402049545 (HB)......Page 5 Table of Contents......Page 7 Preface......Page 11 Biography of Vladimir Andreevich Shevchenko......Page 13 Biography of Vladimir Ivanovich Korogodin......Page 16 Part 1 - Nikolay Wladimirovitch Timoféeff-Ressovsky: the man and the scientist. (1900-1981)......Page 19 TIMOFÉEF-RESSOVSKY: A SHORT ACCOUNT OF HIS LIFE......Page 20 FROM THE MUTATION THEORY TO THE THEORY OF THE MUTATION PROCESS......Page 32 N.V. TIMOFEEFF-RESSOVSKY'S VIEWS AS THE BASIS OF RADIOECOLOGICAL STUDIES......Page 44 LIVING MATTER AND BIOSPHEROLOGY......Page 52 Part 2 - Nuclear accidents and weapons......Page 64 RADIOECOLOGICAL ASSESSMENT OF THE CHNPP ACCIDENT IN THE WESTERN EUROPE AND ADJACENT AREA, WITH SPECIAL REFERENCE TO THE MODERN PROBLEMS OF RADIOECOLOGY IN THE MEDITERRANEAN......Page 65 DOSE RATES AND EFFECTS OF CHRONIC ENVIRONMENTAL RADIATION ON HYDROBIONTS WITHIN THE CHERNOBYL EXCLUSION ZONE......Page 84 EFFECTS OF CONTAMINANT EXPOSURE ON PLANTS......Page 92 VARIABILITY AND VIABILITY OF SEED PLANT POPULATIONS AROUND THE NUCLEAR POWER PLANT......Page 99 RADIOSENSITIVITY OF CHROMOSOME APPARATUS OF VOLES FROM ALIENATION ZONE OF CHERNOBYL'S ACCIDENT......Page 108 STRATEGY OF BIOLOGICAL RADIATION PROTECTION OF BIOTA AT THE RADIONUCLIDE CONTAMINATED TERRITORIES......Page 114 POPULATION-GENETIC CONSEQUENCES OF THE ECOLOGICAL CATASTROPHE (CHERNOBYL'S EXAMPLE)......Page 122 PRINCIPLES AND RESULTS OF GENETIC MONITORING OF CHEMICAL MUTAGENS AND RADIATION EFFECTS IN ARMENIA......Page 140 ESTIMATION OF SOMATIC GENE MUTAGENESIS IN PATIENTS WITH BENIGN TUMORS LIVING IN RADIATION CONTAMINATED REGIONS WITH DIFFERENT [sup(137)] CESIUM DENSITY......Page 150 RADIOLOGICAL HEALTH EFFECTS 20 YEARS AFTER THE CHERNOBYL ACCIDENT: DATA OF THE NATIONAL RADIATION AND EPIDEMIOLOGICAL REGISTRY......Page 155 CASUALTIES AND RADIATION DOSIMETRY OF THE ATOMIC BOMBINGS ON HIROSHIMA AND NAGASAKI......Page 161 Part 3 - Radiation effects: the environment......Page 169 RADIOECOLOGY: HISTORY AND STATE-OF-THE-ART AT THE BEGINNING OF THE 21[sup(st)] CENTURY......Page 170 LOW DOSE RADIATION EFFECTS IN THE ENVIRONMENT: IS THE FEAR OR THE SCIENCE IRRATIONAL?......Page 180 RADIOCAPACITY: CHARACTERISTIC OF STABILITY AND RELIABILITY OF BIOTA IN ECOSYSTEMS......Page 186 TRITIUM IN WATER SYSTEMS OF URAL REGION......Page 197 THE PROBLEM OF MULTIPLE STRESSORS INCLUDING LOW DOSES OF RADIATION IN THE ENVIRONMENT......Page 207 Part 4 - Radiation effects: humans......Page 218 DIRECTED EVOLUTION OF MANKIND AND BIOSPHERE......Page 219 ASSESSMENT OF RADIATION GENETIC RISK IN MAN......Page 227 TARGETS, HITS AND TRACKS......Page 236 RADIATION CYTOGENETICS: THE COLOR REVOLUTION......Page 250 THE MINIMUM DETECTABLE DOSE BY BIODOSIMETRY IN A RADIATION OVEREXPOSURE......Page 260 A SIMPLE METHOD FOR THE EVALUATION OF SIDE DOSES IN RADIOTHERAPY......Page 266 Part 5: Mutations......Page 276 MUTATION AND DNA REPAIR: FROM THE GREEN PAMPHLET TO 2005......Page 277 CANALIZATION AND EVOLVABILITY: TEMPERING THE EFFECTS OF MUTATION IN A CHANGING ENVIRONMENT......Page 288 EFFECTS OF CHRONIC LOW-LEVEL IRRADIATION ON RADIOSENSITIVITY OF MAMMALS: MODELING AND EXPERIMENTAL STUDIES......Page 296 PROLONGED ENVIRONMENTAL STRESS INDUCES MUTATIONS AND PROVIDES NONSPECIFIC ADAPTATION OF DROSOPHILA POPULATIONS......Page 305 MODULATION OF MUTATION RATES AND ADAPTATION OF BACTERIA......Page 313 NUCLEAR CYTOPLASMIC INTERACTION HYPOTHESIS AND THE ROLE OF TRANSLOCATIONS IN NICOTIANA ALLOPOLYPLOIDS......Page 322 MOLECULAR DYNAMICS STUDY OF RADIOSENSITIVE MUTANT ALLELE OF PROTEIN KINASE ycdc28-srm [G20S] USING hcdk2 AS MODEL......Page 330 GENOME RECONSTITUTION IN THE EXTREMELY RADIATION RESISTANT BACTERIUM DEINOCOCCUS RADIODURANS......Page 343 List of Authors......Page 362 In September 2005, Yerevan (Armenia) hosted an International Conference dedicated to the 70th anniversary of the publication of the so called "green paper", published by N.W. Timofeeff-Ressovsky, K. Zimmer and M. Delbruck in 1935, entitled "On the origin of gene mutations and gene structure". The importance of this paper for genetics and radiobiology was enormous - not only for radiobiology, but for genetics in general. The "target" of the radiation action was indeed the "gene", that for the first time found a clear, operational definition. The organisers of this Conference proposed to convene scientists from all over the world to discuss the impact of radiation risk estimates in normal and emergency situations. This was the starting point of the NATO Advanced Research Workshop, whose proceedings are published in this book. The parallel development of the Conference and the Workshop resulted in a true synergism, both events taking advantage of the mixed environment of molecular biologists, genetists, radiobiologists, radioecologists, biophysicists, etc. gathered in Yerevan. We were delighted to include a few excellent papers dealing directly with Timofeeff-Ressovsky's life, and the "green pamphlet". The life and scientific achievements of Timofeeff-Ressovsky are often not well known in western countries, hence we deemed it advisable to include those papers in this book Talks about the paper entitled "On the origin of gene mutations and gene structure", and its importance for genetics and radiobiology, not only for radiobiology, but for genetics in general. This book also discusses the impact of radiation risk estimates in normal and emergency situations