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Psychiatric Genetics is the first book to focus on clinical applications of genetics in psychiatry. It covers issues involved in genetic counseling, the interpretation of familial and genetic information for clinical use, information regarding risks associated with specific psychiatric disorders, and the uses of genetic testing. Written explicitly for practitioners, it offers a clinically relevant resource to help readers interpret the often bewildering flood of information about genetics and to facilitate responding to patients requests to predict the risk of recurrence of psychiatric illness or provide information about reproductive and pregnancy-related issues. The book first presents a framework for understanding and critically evaluating psychiatric genetic research literature, then provides guidelines for genetic counseling. Subsequent chapters summarize genetic aspects of major psychiatric conditions from childhood-onset disorders through psychotic, mood, and anxiety disorders to dementia as well as neuropsychiatric manifestations of other genetic disorders. Risk/benefit considerations related to medication use during pregnancy are then presented. Coverage of ethical, legal, and social implications illustrates the dilemmas that arise with advances in genetic research. Whether used as a clinical guide, reference, or ancillary text, Psychiatric Genetics provides the most up-to-date source on the impact of this growing field on everyday psychiatric practice.

as More Patients Seek Information About Family Risks Of Psychiatric Illness—an Interest Likely To Increase As Gene-identification Studies Are Publicized—most Psychiatrists Agree It Is Their Role To Discuss These Issues But Admit They Are Ill-prepared To Do So. psychiatric Genetics Addresses That Need As The First Book To Focus On Clinical Applications Of Genetics In Psychiatry. It Covers Issues Involved In Genetic Counseling, The Interpretation Of Familial And Genetic Information For Clinical Use, Information Regarding Risks Associated With Specific Psychiatric Disorders, Risk/benefit Considerations Related To Medication Use During Pregnancy, And The Ethical And Social Implications Of Psychiatric Genetic Knowledge And Research—including The Prospects For Genetic Testing.

while Other Books Have Been Written For The Genetics Community, This Volume Is Addressed To Practitioners: A Clinically Relevant Resource That Can Help Them Understand The Often Bewildering Flood Of Information About Genetics—information Difficult To Interpret, Let Alone Integrate Into Practice—and Enable Them To Respond To Patients’ Requests To Predict The Risk Of Recurrence Of Psychiatric Illness Or Provide Information About Reproductive And Pregnancy-related Issues. Experts From Psychiatry, Genetic Epidemiology, Molecular Genetics, Genetic Counseling, Cognitive Psychology, And Ethics Focus On Issues That Have Received Little Attention Elsewhere Yet Are Of Increasing Importance To Clinicians. Written At A Level That Assumes No Particular Expertise In Genetics, The Book Features These Immediately Applicable Benefits:

• It Offers A Framework For Understanding And Critically Evaluating The Psychiatric Genetic Research Literature, Enabling Clinicians To Better Understand The Meaning And Limitations Of Genetic Discoveries When Patients Raise Questions About Media Reports.
• It Provides A Resource For Clinicians Who Would Like More Information About The Role And Content Of Genetic Counseling, Outlining A Typical Counseling Session While Demonstrating How Risks Are Estimated And Discussed.
• It Summarizes Genetic Aspects Of Major Psychiatric Conditions—from Childhood-onset Disorders Through Psychotic, Mood, And Anxiety Disorders To Dementia—as Well As Neuropsychiatric Manifestations Of Other Genetic Disorders.
• It Alerts Clinicians To Risk/benefit Considerations Related To Medication Use During Pregnancy.
• It Covers The Ethical, Legal, And Social Implications Of Genetic Research And Counseling, Illustrating The Dilemmas That Arise With New Advances.

whether Used As A Clinical Guide, Reference, Or Ancillary Text, This Book Sets The Standard For The Application Of Psychiatric Genetic Knowledge In Everyday Practice. Psychiatrists, Mental Health Clinicians, And Genetic Counselors Will Find It An Essential Resource For All Patient Encounters In Which Genetic Issues Arise.

doody Review Services

reviewer:raj Tummala, Md(wyeth Pharmaceuticals)
description:this Is A Comprehensive And Focused Review Of The Clinical And Practical Applications Of Genetics In Psychiatric Disorders.
purpose:the Purpose Is To Provide An Interpretive Review Of The Growing Field Of Genetics And Its Practical Applications For Clinicians Treating Various Psychiatric Disorders.
audience:the Audience Includes Anyone Dealing With Psychiatric Patients Including Students, Clinicians, Researchers, Etc.
features:genetics As A Field Of Research Has Been Exploding Over The Last Decade, Giving Us Some Insight Into The Pathophysiology Of Psychiatric Disorders. In This Book, The Authors Provide A Nice Overview Of The Recent Advances In Psychiatric Genetics And Their Application To Clinical Practice. A Primer On Genetics With A Discussion Of Methods, Genetic Linkage, And Association Analyses Leads Into The Principles Of Genetic Counseling. Each Section Is In The Format Of A Question With A Detailed Answer. Evidence Is From Genetic Studies That Are Listed As Well As From Simple To Understand Case Vignettes. Risk Communication Is Presented In Verbal, Numerical, And Visual Formats. The Genetics Of Specific Psychiatric Disorders Covers Childhood Onset Disorders, Psychotic Disorders, Mood And Anxiety Disorders, And Alzheimer's Disease. Each Disease State Is Discussed In Detail With Clinical Phenotypes, Genetic Epidemiology With Family, Twin, And Adoption Studies. Of Special Note Are The Chapters On The Neuropsychiatric Aspects Of Various Genetic Disorders And Perinatal Psychiatry And Teratogenicity. The Ethical, Legal, And Social Implications Such As Genetic Testing/profiling Are Nicely Covered. Each Chapter Has A Detailed Reference Section. Information Is Highlighted In The Form Of Tables, Graphs, And Pictures To Add Clarity.
assessment:this Is A Very Well Written, Focused Review Covering The Major Aspects Of Genetics As They Apply To Psychiatric Disorders. The Book Is Easy To Read With A Clinical And Practical Twist.

As more patients seek information about family risks of psychiatric illness -- an interest likely to increase as gene-identification studies are publicized -- most psychiatrists agree it is their role to discuss these issues but admit they are ill-prepared to do so. Psychiatric Genetics addresses that need as the first book to focus on clinical applications of genetics in psychiatry. It covers issues involved in genetic counseling, the interpretation of familial and genetic information for clinical use, information regarding risks associated with specific psychiatric disorders, risk/benefit considerations related to medication use during pregnancy, and the ethical and social implications of psychiatric genetic knowledge and research -- including the prospects for genetic testing.While other books have been written for the genetics community, this volume is addressed to practitioners: a clinically relevant resource that can help them understand the often bewildering flood of information about genetics -- information difficult to interpret, let alone integrate into practice -- and enable them to respond to patients'requests to predict the risk of recurrence of psychiatric illness or provide information about reproductive and pregnancy-related issues. Experts from psychiatry, genetic epidemiology, molecular genetics, genetic counseling, cognitive psychology, and ethics focus on issues that have received little attention elsewhere yet are of increasing importance to clinicians. Written at a level that assumes no particular expertise in genetics, the book features these immediately applicable benefits: • It offers a framework for understanding and critically evaluating the psychiatric genetic research literature, enabling clinicians to better understand the meaning and limitations of genetic discoveries when patients raise questions about media reports. • It provides a resource for clinicians who would like more information about the role and content of genetic counseling, outlining a typical counseling session while demonstrating how risks are estimated and discussed.• It summarizes genetic aspects of major psychiatric conditions -- from childhood-onset disorders through psychotic, mood, and anxiety disorders to dementia -- as well as neuropsychiatric manifestations of other genetic disorders.• It alerts clinicians to risk/benefit considerations related to medication use during pregnancy.• It covers the ethical, legal, and social implications of genetic research and counseling, illustrating the dilemmas that arise with new advances. Whether used as a clinical guide, reference, or ancillary text, this book sets the standard for the application of psychiatric genetic knowledge in everyday practice. Psychiatrists, mental health clinicians, and genetic counselors will find it an essential resource for all patient encounters in which genetic issues arise. Contents......Page 6 Contributors......Page 8 Preface......Page 12 Part 1: General Principles......Page 16 1 Psychiatric Genetics: A Primer......Page 18 2 Principles of Genetic Counseling......Page 42 3 Risk Communication: Simple Tools to Foster Understanding......Page 62 Part 2: Genetics of Specific Disorders......Page 82 4 Genetics of Childhood-Onset Psychiatric Disorders......Page 84 5 Genetics of Schizophrenia and Psychotic Disorders......Page 114 6 Genetics of Mood and Anxiety Disorders......Page 146 7 Genetics of Alzheimer's Disease......Page 192 8 Neuropsychiatric Aspects of Genetic Disorders......Page 210 Part 3: Special Topics......Page 240 9 Perinatal Psychiatry and Teratogenicity......Page 242 10 Ethical, Legal, and Social Implications of Psychiatric Genetics and Genetic Counseling......Page 270 11 The Road Ahead......Page 292 Glossary......Page 320 A......Page 322 C......Page 324 D......Page 325 F......Page 327 G......Page 328 I......Page 330 M......Page 331 N......Page 332 P......Page 333 R......Page 335 S......Page 336 T......Page 337 Z......Page 338 Psychiatric genetics: a primer / Stephen J. Glatt, Stephen V. Faraone, and Ming T. Tsuang Principles of genetic counseling / Holly L. Peay and Beth Rosen Sheidley Risk communication: simple tools to foster understanding / Stephanie Kurzenhäuser and Anja Dieckmann Genetics of childhood-onset psychiatric disorders / S. Evelyn Stewart and David L. Pauls Genetics of schizophrenia and psychotic disorders / Anne S. Bassett, Eva W.C. Chow, and Kathleen A. Hodgkinson Genetics of mood and anxiety disorders / Jordan W. Smoller Genetics of Alzheimer's disease / Matthew B. McQueen and Deborah Blacker Neuropsychiatric aspects of genetic disorders / Christine T. Finn Perinatal psychiatry and teratogenicity / Alexia Koukopolous ... [et al.] Ethical, legal, and social implications of psychiatric genetics and genetic counseling / Steven K. Hoge and Paul S. Appelbaum The road ahead / Jordan W. Smoller and Bruce R. Korf. This book focus is on the clinical applications of genetics in psychiatry. It covers issues involved in genetic counseling, the interpretation of familial and genetic information for clinical use, information regarding risks associated with specific psychiatric disorders, and the uses of genetic testing. Written explicitly for practitioners, it offers a clinically relevant resource to help readers interpret the often bewildering flood of information about genetics and to facilitate responding to patients' requests to predict the risk of recurrence of psychiatric illness or provide information about reproductive and pregnancy-related issues. Coverage of ethical, legal, and social implications illustrates the dilemmas that arise with advances in genetic research.