Pseudomonas: Volume 2: Virulence and Gene Regulation (Advances in Experimental Medicine & Biology)

Pseudomonas comprises three volumes covering the biology of pseudomonads in a wide context, including the niches they inhabit, the taxonomic relations among members of this group, the molecular biology of gene expression in different niches and under different environmental conditions, the analysis of virulence traits in plants, animals and human pathogens as well as the determinants that make some strains useful for biotechnological applications and promotion of plant growth. There has been growing interest in pseudomonads and a particular urge to understand the biology underlying the complex metabolism of these ubiquitous microbes. These bacteria are capable of colonizing a wide range of niches, including the soil, the plant rhizosphere and phylosphere, and animal tissues; more recently they have attracted attention because of their capacity to form biofilms, a characteristic with potentially important medical and environmental implications. The three volumes cover the following topics: - Taxonomy, - Genomics, - Life styles, - Cell Architecture, - Virulence, - Regulation, - Macromolecules, - Alternative Respiratory Substrates, - Catabolism and Biotransformations. Pseudomonas will be of use to all researchers working on these bacteria, particularly those studying microbiology, plant crops, pathogenesis, and chemical engineering. Advanced students in biology, medicine and agronomy will also find these three volumes a valuable reference during their studies. Front Matter....Pages i-xvii Front Matter....Pages 1-1 Virulence Factors in Pseudomonas Aeruginosa ....Pages 3-45 ATP-Utilizing Enzymes, Purinergic Receptor Modulation, Cupredoxins and Mammalian Cell Death....Pages 47-67 Iron Regulation and Siderophore Signalling in Virulence by Pseudomonas Aeruginosa ....Pages 69-123 New Insights Into the Biosynthesis, Mode of Action, and Regulation of Syringomycin, syringopeptin, and Coronatine....Pages 125-158 Current Ideas on the Genetics and Regulation of the Synthesis of Phaseolotoxin in Pseudomonas Syringae PV. Phaseolicola....Pages 159-180 The Type III Secretion Systems of Plant-Associated Pseudomonads: Genes and Proteins on the Move....Pages 181-219 Front Matter....Pages 221-221 Global Regulation in Pseudomonas Syringae ....Pages 223-238 Post-Transcriptional Regulation in Pseudomonas SPP. Via the Gac/Rsm Regulatory Network....Pages 239-255 Two-Component Signal Transduction Systems: A Key to the Adaptative Potential of Pseudomonas Aeruginosa ....Pages 257-288 Transcription Mediated By rpoN -Dependent Promoters....Pages 289-317 Compiling Sigma-70-Dependent Promoters....Pages 319-343 Compiling Extracytoplasmic Function (ECF) Sigma Factors Regulated Promoters in Pseudomonas ....Pages 345-363 Catabolite Repression and Physiological Control....Pages 365-387 Regulation of Pseudomonas Aeruginosa Exotoxin a Synthesis....Pages 389-423 Lessons from the ami Operon....Pages 425-449 Transcriptional Regulation and Catabolic Strategies of Phenol Degradative Pathways....Pages 451-477 Enzymatic Activation of the cis-trans Isomerase and Transcriptional Regulation of Efflux Pumps in Solvent Tolerance in Pseudomonas Putida ....Pages 479-508 Transcriptional Regulation of the Toluene Catabolic Pathways....Pages 509-537 Back Matter....Pages 539-553 v. 1. Genomics, life style and molecular architecture v. 2. Virulence and gene regulation v. 3. Biosynthesis of macromolecules and molecular metabolism v. 4. Molecular biology of emerging issues v. 5. A model system in biology.