Protides of the Biological Fluids : Proceedings of the Twenty-Second Colloquium, Brugge, 1974

Proteins and Related Subjects, Volume 22: Protides of Biological Fluids covers the proteins of the intercellular matrix, along with the genetic defects and polymorphism of the human plasma proteins and isotachophoresis. The text first deals with the connective tissue proteins, along with the anabolic and catabolic enzymes of connective tissues. Next, the selection details the isolation and purification of various proteins, their metabolism, and function. The text also talks about the genetic defects and polymorphism of human plasma proteins, which includes the abnormalities of specific proteins. The last section covers the utilization of isotachophoresis as an analytical tool for the detection and characterization of amino acids, low-weight metabolites, and proteins. The book will be of great use to students, researchers, and practitioners of biological science. Content: List of Committee Members , Page ii Front Matter , Page iii Copyright , Page iv Preface , Page xvii Acknowledgements , Page xviii Relation between Structure and Biologic Function of the Protease Inhibitors in the Extracellular Fluid , Pages 3-12 , C.-B. LAURELL Cellular Differentiation and the Morphogenesis of the Intercellular Matrix , Pages 15-21 , BARBARA ROBERT, LADISLAS ROBERT The Role of Extracellular Matrix Macromolecules upon Cell Differentiation , Pages 23-32 , H.C. SLAVKIN, R.D. CROISSANT, H. GUENTHER Ultrastructural Study of the Fibroblastic Activities of Multipotent Cells in the Mollusc : Helix aspersa M , Pages 33-39 , MAX PAVANS DE CECCATTY, MARIE-THéRèSE NICOLAS Isolation and Culture Techniques of Fetal Calf Chondrocytes , Pages 41-45 , SVEN BJöRNSSON, DICK HEINEGåRD Control of Ameloblasts Cytodifferentiation , Pages 47-50 , J.V. RUCH, V. KARCHER-DJURICIC Periaxial Extracellular Material and Vertebral Chondrogenesis , Pages 51-58 , G. STRUDEL Collagen Resorption in Sponges: Involvement of Bacteria and Macrophages , Pages 59-63 , ROBERT GARRONE Calcite and Collagen in the Skeleton of the Cnidaria Veretillum cynomorium Pall. (Anthozoa. Pennatulidae) , Pages 65-69 , SUZANNE FRANC, ALAIN HUC, GEORGES CHASSAGNE Influence of Some Purified Plasma Proteins on Collagen Synthesis in vitro , Pages 71-74 , J.P. BOREL, A. VIEILLARD, C. LOMBART, M.F. JAYLE In vitro Effects of D(—)penicillamine on Collagen Synthesis by Human Fibroblasts , Pages 75-78 , W. HARVEY, R. GRAHAME, P.A. TOSELAND, G.S. PANAYI Studies on Collagen in the Developing Arteries of the Chick , Pages 79-82 , M.J. BARNES, L.F. MORTON Post-translational Processing of Procollagen Polypeptides , Pages 83-85 , RICHARD HARWOOD, MICHAEL E. GRANT, DAVID S. JACKSON The Function of Borohydride Reducible Components of Collagen , Pages 87-90 , A.J. BAILEY, S.P. ROBINS, G. BALIAN Stability of Collagens from Articular Cartilage and from the Heart Valves of Pigs. Study of Collagen—Proteoglycan Interactions , Pages 91-95 , A. HUC, P. MANNSCHOTT, D. HERBAGE, M. WEISS Confirmation and Additional Features of the Planar Waveform in Collagen Fibres , Pages 97-100 , L.J. GATHERCOLE, A. KELLER Identification of Two Molecular Species of Collagen in Mammalian Intervertebral Disc , Pages 101-106 , DAVID R. EYRE, HELEN MUIR Collagen Crosslinking in Inflamed Tissues , Pages 107-110 , S. BAZIN, A.J. BAILEY, A. DELAUNAY Collagen and Proteoglycans Extraction from Normal and Osteo-arthritic Human Articular Cartilage , Pages 111-115 , D. HERBAGE, C. MICHEL, A. HUC Bone in Dermatosparaxis , Pages 117-120 , B. NUSGENS, A. DHEM Urinary Excretion of Hydroxylysyl Glycosides as an Index of Collagen Metabolism in Disease , Pages 121-125 , R. ASKENASI Non-polar Peptides from Elastin , Pages 127-135 , STEPHEN KELLER, INES MANDL The Ultrastructural Organization of Elastin , Pages 137-144 , L. GOTTE, D. VOLPIN Isolation of Chemically Pure Elastins in a Form Suitable for Mechanical Testing , Pages 145-148 , F.S. STEVEN, R.J. MINNS Electron Microscopical Studies on the Role of Microfibrils in Elastogenesis , Pages 149-155 , ANNA KáDáR, BARBARA ROBERT Organ-Culture Studies on the Biosynthesis of Intercellular Macromolecules of Aorta , Pages 157-159 , M. MOCZAR, J. OUZILOU, Y. COURTOIS, L. ROBERT Isolation and Characterization of a Highly Cross-linked Peptide of Elastin from Porcine Aorta , Pages 161-165 , K. HAN, M. DAVRIL, Y. MOSCHETTO, G. BISERTE Characterization of Lipid Classes associated with Elastin Isolated from Normal and Pathological Human Aorta , Pages 167-170 , M. CLAIRE, B. JACOTOT, L. ROBERT, J.L. BEAUMONT Structure and Aggregation of Proteoglycans of Cartilage , Pages 171-176 , JOHN D. GREGORY Structure of Cartilage Proteoglycans and Their Interaction with Some Intercellular Matrix Components , Pages 177-182 , DICK HEINEGåRD, VINCENT C. HASCALL Structure of L-iduronic Acid-Sulphate-containing Oligosaccharides from Pig Skin Dermatan Sulphate , Pages 183-191 , L.–A. FRANSSON, L. CöSTER, B. HAVSMARK, A. MALM STRöM, I. SJöBERG Chemical and Electron Microscopic Studies on Proteoglycans of Guinea Pig Costal Cartilage , Pages 193-199 , STEFAN LOHMANDER, JOHAN THYBERG Gel Electrophoresis of Proteoglycans and Collagen from Normal and Abnormal Growth Cartilage , Pages 201-204 , V. STANESCU, P. MAROTEAUX The Control of the Early Steps in Polysaccharide Synthesis , Pages 205-211 , C. PHELPS, R. STEVENS, AILEEN YOUNG, MILLIE LUSCOMBE UDP-Glucose: A Key Branch-point in the Regulation of Glycosaminoglycan Biosynthesis , Pages 213-217 , C. BALDUINI, G. DE LUCA, P. SPEZIALE, A.A. CASTELLANI Different Types of Chondroitin Sulfate-Dermatan Sulfate Hybrids in Arterial Tissue , Pages 219-226 , ECKHART BUDDECKE, KURT VON FIGURA Incorporation of N-acetyl-D(I 14 C)-Glucosamine in the Cartilage of a Selacian , Scyliorhinus canicula , Pages 227-231 , J. BOCQUET, J.-P. PUJOL Biosynthesis of Acid Mucopolysaccharides by the Surviving Newborn Rat Skin , Pages 233-237 , B. HERVE, H. CLAUSER Biosynthesis of Chondroitin Sulfate Proteins. Isolation of an Insoluble Priming Pool Feeding One Collagen-bound and Three Soluble Pools with Heterogeneous Proteoglycans , Pages 239-243 , TILMANN O. KLEINE, JOACHIM WUNSCH The Variations of Bovine Cartilage Proteoglycans with Age , Pages 245-249 , SVEN LARSSON, DICK HEINEGåRD Distribution and Biosynthesis of Glycosaminoglycans in Arterial Wall , Pages 251-254 , J. PICARD, P. LEVY, B. HERMELIN, A. PAUL-GARDAIS, E. DEUDON Acid Mucopolysaccharides in Normal and Atherosclerotic Tissues: A Comparative Study , Pages 255-257 , F.B. KLYNSTRA Analysis of Urinary Mucopolysaccharides from Mucopolysaccharidose Cases by Gas-Liquid Chromatography , Pages 259-262 , J.C. ANDERSON, L.M. SHAPIRO, MARGARET A. TAYLOR Sulfatase Deficiencies in Mucopolysaccharidoses , Pages 263-267 , H. KRESSE, K. VON FIGURA The Proteoglycans of Articular Cartilage in Early Experimental Osteoarthrosis , Pages 269-274 , C.A. McDEVITT, H. MUIR Specificity of Pinocytosis of α-N-acetylglucosaminidase by Fibroblasts , Pages 275-278 , K. VON FIGURA, H. KRESSE The Effect of O-β-hydroxyaethylrutoside and (+)-catechine on Sulfate Incorporation of Fibroblasts in Tissue Culture , Pages 279-282 , R. WINAND, J. LESPAGNARD Isolation and Primary Characterization of a Non-collagenous Reticulin Component , Pages 283-285 , M. PRAS, E.L. GLYNN The Isolation and Characterization of Non-Collagenous Proteins from the Intercellular Matrix , Pages 287-289 , J.C. ANDERSON, V. LEE-OWN Isolation and Structural Study of Glycoproteins associated with Rabbit and Rat Dermis Collagen , Pages 291-296 , J. CORNILLET-STOUPY, A. VIEILLARD, A. RANDOUX Structural Glycoproteins from Connective Tissues , Pages 297-302 , E. MOCZAR, C. SEPULCHRE, M. MOCZAR An Immunohistological Study of the Distribution of Immunoglobulins, Collagen and Contractile Proteins in Human Placentae , Pages 303-307 , W. PAGE FAULK, L.B. CONOCHIE, P. TRENCHEV, J. DORLING Human Serum Low Density Lipoglycoproteins: Carbohydrate Composition in Health and Disease , Pages 309-314 , P. VAN DER BIJL Interaction between Plasma Proteins and the Intercellular Matrix in Human Aortic Intima , Pages 315-318 , ELSPETH B. SMITH, D.C. CROTHERS Thermoanalytical Studies on the Intercellular Matrix of the Vessel Wall , Pages 319-322 , M. BIHARI-VARGA, S. GERö Studies on the Regulation of the Biosynthesis of the Intercellular Macromolecules of the Corneal Stroma , Pages 323-326 , M. MENASCHE, P. PAYRAU, L. ROBERT Water – Soluble Proteins from Egg-Shell Matrices , Pages 327-331 , G. KRAMPITZ, J. ENGELS Pseudomyxomatous Mucin: Characterization of a Non-compatible A Blood Group Activity in the Products of Pronase Digestion , Pages 333-335 , J. PICARD, A. PAUL-GARDAIS Isolation and Characterization of Structural Glycoproteins from Sponges , Pages 337-341 , S. JUNQUA, J. FAYOLLE, L. ROBERT Functional Role of the Macromolecules of the Intercellular Matrix in the Blood—Brain Barrier , Pages 343-348 , A.M. ROBERT, G. GODEAU, M. MISKULIN Selective Cleavage of Basement Membrane Proteins at the Carboxyl Peptide Linkages of Methionine and at the Amino Peptide Linkages of Cysteine Residues , Pages 349-356 , N.A. KEFALIDES, E. TOMICHEK, R. ALPER Basement Membrane Synthesis, Accumulation and Turnover in vitro , Pages 357-361 , R.R. MINOR, C.C. CLARK, T.R. KOSZALKA, R.L. BRENT, N.A. KEFALIDES An Intercellular Component of the Nervous System , Pages 363-366 , B. DELPECH, C. CHAUZY, A. DELPECH, R. MAUNOURY Primary Structure of Glycopeptide Antigenic Site Isolated from Glomerular Basement Membrane , Pages 367-371 , P. MAHIEU, J. FOIDART-WILLEMS, G. MAGHUIN-ROGISTER, J. SALMON Possible Mechanisms of Collagen Breakdown in Higher Animals , Pages 373-377 , L. STRAUCH Collagenases from Lower Organisms , Pages 379-389 , L. STRAUCH The Precursor of Bone Collagenase and its Activation , Pages 391-397 , G. VAES, Y. EECKHOUT Existence of a Collagen Synthetase in the Microsomal Membranes of Rat Liver , Pages 399-404 , G. BERTHILLIER, R. GOT Collagenolytic Enzymes in Invasion Zones of Tumours , Pages 405-407 , E. KEIDITSCH, L. STRAUCH Induction of Collagenolytic Enzymes and Catalase in Ascites Cells Growing as Solid Invasive Tumour , Pages 409-412 , D. KAYSER, L. STRAUCH, E. KEIDITSCH Aortic Elastase, Its Role in the Degradation of Arterial Elastin , Pages 413-418 , B. ROBERT, L. ROBERT Purification and Characterization of Human Blood Platelet Elastase , Pages 419-424 , Y. LEGRAND, B. ROBERT Change of Seric Inhibiting Power against Elastase in Experimental Atherosclerosis , Pages 425-430 , M. RABAUD, J. LARRUE, H. BRICAUD Degradation of Chondroitin Sulphate by Lysosomal Enzymes from Embryonic Chick Cartilage , Pages 431-435 , å. WASTESON, R. AMADò, B. INGMAR, C.-H. HELDIN The Possible Function of Lysozyme in Cartilage Metabolism , Pages 437-440 , K.E. KUETTNER, N. SORGENTE, R. EISENSTEIN, J.C. PITA, D.S. HOWELL Specificity Requirements of Lysyl Oxidase , Pages 441-444 , B.N. BACHRA, A.J. BAARS, G.D.N.E. VIANDEN Biological and Medical Aspects of Inherited Protein Polymorphism , Pages 447-452 , H. CLEVE Regulation of Plasma Protein Synthesis in Cultured Embryonic Chick-liver Cells: Lack of Translational Control , Pages 453-457 , G.E. GRIENINGER, S. GRANICK Post-synthetic Isomerization of Rabbit Serum Albumin in vivo , Pages 459-463 , K. WALLEVIK Plasma Albumin Polymorphism in Fowl. A System for the Study of Albumin Biosynthesis and Its Control , Pages 465-470 , M. FRIED, H.M. JERNIGAN Jr., G.W. LaMONDA Analbuminaemia , Pages 471-474 , HANS H. OTT Alloalbumin B and its Subtypes , Pages 475-476 , H.H. OTT, S. SANDKüHLER, W. MüLLER-BEISSENHIRTZ The Differential Binding of Bromophenol Blue studied in six new Propositi with Bisalbuminaemia of the Al Ge Type , Pages 477-480 , R.J. WIEME, M. RABAEY, J. SEGERS Simultaneous Turnover Studies of the Two Albumin Components Alternatively Labelled with 125 I and 131 I in Human Bisalbuminaemia , Pages 481-487 , R. BIANCHI, G. MARIANI, A. PILO, M.G. TONI, G. MICHELI The Pi System: Polymorphism of Alpha-1-Antitrypsin , Pages 489-492 , J.P. MARTIN Pi Typing Techniques , Pages 493-495 , M.K. FAGERHOL Antitryptic Activity of Alpha 1 -antitrypsin Pi Bands in Starch Gel , Pages 497-499 , C.E. LANGLEY, R.C. TALAMO α 1 - Antitrypsin Deficiency: Pi Genotype ZO, SO and MO , Pages 501-503 , T. SVEGER, C.-B. LAURELL, C.-G. LJUNGGREN Structural Differences Between Pi-Types of α 1 - antitrypsin , Pages 505-509 , J.O. JEPPSSON, C.B. LAURELL Chemical Properties of α 1 - antitrypsin , Pages 511-514 , E.C. KLASEN, A.M. BOGAART, L.F. BERNINI The Pi System: Its Study by means of Thin-Layer-Gel Electrofocusing in Polyacrylamide Gel , Pages 515-520 , Ph. ARNAUD, C. CHAPUIS-CELLIER, R. CREYSSEL α 1 -Antitrypsin (Pi) Phenotypes in Neonatal Liver Disease , Pages 521-525 , A. MILFORD WARD Genetic Complement Defects in Man , Pages 527-534 , K. ROTHER, H. GEIGER, U. ROTHER, G. TILL The Role of Complement in Immune Hemolysis in vitro and in vivo , Pages 535-540 , L.D. PETZ Hidden C3-Variants and Diverse Phenotypes of Unconverted and Converted C3 , Pages 541-546 , G. MAUFF, G. PULVERER, W. OPFERKUCH, K. HUMMEL The Metabolism of Radiolabelled C3 ( 125 I-C3) in Autoimmune Disorders , Pages 547-550 , L.D. PETZ, N.R. COOPER, R. POWERS, J. FRIES Critical Factors for the Immunochemical Quantitation of the Third Complement Component C3 , Pages 551-554 , P. SPATH, F. GABL A New Type of Very Slow C3 , Pages 555-558 , J. SEGERS, R.J. WIEME, M. RABAEY, CH. RITTNER The Frequency of the Polymorphisms of C3 in the Swiss Population and Some Remarks on the Identification of Rare Phenotypes , Pages 559-562 , R. PFLUGSHAUPT, R. SCHERZ, L. STEINEGGER, R. BüTLER Sources of error in C3-typing by High-voltage Agarose Gel Electrophoresis , Pages 563-566 , P. KüHNL, ST. STROBEL C2 Deficiency in Man , Pages 567-574 , M.R. KLEMPERER Polymorphism of Human C6 , Pages 575-580 , M.J. HOBART, P.J. LACHMANN, C.A. ALPER C7 Deficiency in Man , Pages 581-584 , A.J. HANNEMA, K.W. PONDMAN, U. DöHMANN, H. GADNER, L.J. DOOREN A Modified Technique in Typing Pt Proteins , Pages 585-588 , K. HUMMEL, W. MITTELSTAEDT Structural Characterization and Genetic Variation of Haptoglobin , Pages 589-595 , D.R. BARNETT, A. KUROSKY, G.M. FULLER, K. HAN-HWA, M.A. RASCO, B.H. BOWMAN Comparison of the Primary Structure of the β-Chain of Haptoglobin with Serine Proteases , Pages 597-602 , A. KUROSKY, K. HAN-HWA, D.R. BARNETT, M. RASCO, B. TOUCHSTONE, B.H. BOWMAN Structural Aspects of Haemoglobin/Haptoglobin Interaction , Pages 603-606 , B. D'UDINE, L.F. BERNINI Formation of Haptoglobin—Haemoglobin Complex in Inactivated Sera , Pages 607-610 , ö. HEVéR Close Linkage Between LCAT (Lecithin: Cholesterol Acyltransferase) Locus and α-Haptoglobin Locus on Chromosome No. 16 , Pages 611-614 , P. TEISBERG, E. GJONE, B. OLAISEN Genetic Variations in Serum Lipoproteins , Pages 615-620 , KåRE BERG Computer Model of Lipoprotein Metabolism in Hyperlipoproteinemia , Pages 621-625 , M. FRIED, W.R. FISHER, MARY G. HAMMOND, J.A. BOWDEN, M. BERMAN, R.D. PHAIR Recent Progress in the Investigation of the Ag-System of Betalipoproteins , Pages 627-632 , R. BUTLER, E. BRUNNER, R. PFLUGSHAUPT The Relation of Artefactual and Real Polymorphism of Human Ceruloplasmin to its Polypeptide Chain and Carbohydrate Structure , Pages 633-639 , LARS RYDéN Various Types of Congenital Fibrinogen Defects , Pages 641-644 , D. MENACHE, M.H. DENNINGER, M.C. GUILLIN Urinary Fibrin Split Products in Experimental and Human Glomerulonephritis , Pages 645-648 , G. LAGRUE, G. HIRBEC, A. BRANELLEC, M. HEILMAN-GOUAULT, M. LEVENT Association of Typhoid Fever and Response to Vaccination with Polymorphic Systems in Man , Pages 649-653 , SARAH NEVO On the Occurrence of a Genetically Determined “Third” Beta-Globulin , Pages 655-658 , G. POPELIER Analytical Isotachophoresis—Principles of Separation and Detection , Pages 661-667 , L. ARLINGER Free Displacement Electrophoresis (Isotachophoresis) , Pages 669-672 , S. HJERTéN Potential Use of Isotachophoresis in Space , Pages 673-678 , M. BIER, J.O.N. HINCKLEY, A.J.K. SMOLKA, R.S. SNYDER Preparative Isotachophoresis of Membrane Proteins in Solubilizing and Dissociating Media , Pages 679-684 , T.C. BøG-HANSEN, P. JUST SVENDSEN, O.J. BJERRUM, C.S. NIELSEN, J. RAMLAU Preparative Isotachophoresis Combined with Biospecific Interaction and Neuraminidase Treatment in Purification of Human Serum Cholinesterase , Pages 685-689 , C.-H. BROGREN, P. JUST SVENDSEN Analytical Isotachophoresis in Capillary Tubes: Separation of Human Haemoglobin , Pages 691-695 , L. ARLINGER Isotachophoresis of Human Apo-HDL Polypeptides , Pages 697-700 , M.Y. ROSSENEU, V. BLATON, H. CASTER, H. PEETERS, A. KOPWILLEM The Application of Steady-State Stacking to Macromolecular Fractionation by Polyacrylamide Gel Electrophoresis , Pages 701-713 , A. CHRAMBACH, J.S. SKYLER Purification Control of Synthetic Peptides by Means of Analytical Isotachophoresis , Pages 715-719 , ANN KOPWILLEM Conductometric Detection During Isotachophoresis , Pages 721-726 , F.M. EVERAERTS, P. PROSé, TH.P.E.M. VERHEGGEN Isotachophoretic Studies of Adenosine Phosphates and Divalent Cations of Perfused Mouse Liver Cells , Pages 727-732 , J.P.D. DUNN, R.B. KEMP Isotachophoresis: A New Technique for Determination of Tissue Metabolite Concentrations , Pages 733-736 , B. SJöDIN, A. KOPWILLEM, J. KARLSSON Analytical Isotachophoresis in capillary tubes: Preliminary study of Phenylketonuric Sera , Pages 737-742 , A. KOPWILLEM, H. LUNDIN, A.B.B. RIGHETTI, P.G. RIGHETTI Detection of Traces of Proteins by Isotachophoresis , Pages 743-747 , K. UYTTENDAELE, M. DE GROOTE, V. BLATON, H. PEETERS, F. ALEXANDER Author Index , Pages 749-750 Subject Index , Pages 751-753