Proteins of the cerebrospinal fluid : analysis and interpretation in the diagnosis and treatment of neurological disease

The analysis of the protein content of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including Multiple Sclerosis and Encephalitis. This book is a complete revision of the first edition published 16 years ago and reflects the advances in the field in that period. Containing the most comprehensive reference list available today with over 1300 references cross-indexed according to topics, it also includes many classical works that cannot be easily found through the public literature database (like PubMed). This book covers new areas of research such as the use of the analysis of protein content in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes). With many new or completely revised illustrations, this book serves as not only a reference on the topic, but also a lab manual for bench work with recipes, and a clinical reference on individual diseases. * Introduces the Eastern blotting, the technique considered the "gold standard" by the US Food & Drug Administration (FDA) for the demonstration of IgG by immunofixation following isoelectric focusing* Provides numerous tables for ease-of-use* Extensively cross-referenced with over 1300 references The analysis of the proteins of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including multiple sclerosis and encephalitis. This book is a complete revision of the first edition published 16 years ago and reflects the advances in the field over that period.The book contains the most comprehensive reference list available today with over 1300 references cross-indexed according to topics. Many classical works are included that cannot be easily found through public literature databases (like PubMed). Many illustrations are new or completely revised.Many new areas of research are covered in this updated text, including the analysis of proteins in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes).The author is a major international researcher in the field of CSF proteins. His laboratory is recognized as a Marie Curie Training Laboratory for the study of CSF proteins in neurology. In the United States, the method of isoelectric focusing followed by immunofixation as developed by Professor Thompson's laboratory has recently been recognized by the Food & Drug Administration (FDA) as the preferred method for diagnosing multiple sclerosis by the analysis of CSF. Thompson has more than 33 years of experience in the analysis and interpretation of over 100,000 CSF findings in the full array of neurological diseases.The National Hospital for Neurology & Neurosurgery in London has been an international beacon for neurology for many decades. The Institute of Neurology is the academic arm of the Hospital and is part of University College London, which is second only to the University of Cambridge in its ability to attract funding for research. The analysis of the protein content of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including Multiple Sclerosis and Encephalitis. Proteins of the Cerebrospinal Fluid is a complete revision of the first edition published 16 years ago and reflects the advances in the field in that period. Containing the most comprehensive reference list available today with over 1300 references cross-indexed according to topics, it also includes many classical works that cannot be easily found through the public literature database (like PubMed). This book covers new areas of research such as the use of the analysis of protein content in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes). With many new or completely revised illustrations, this book serves as not only a reference on the topic, but also a lab manual for bench work with recipes, and a clinical reference on individual diseases. Introduces the Eastern blotting, the technique considered the "gold standard" by the US Food & Drug Administration (FDA) for the demonstration of IgG by immunofixation following isoelectric focusing Provides numerous tables for ease-of-use Extensively cross-referenced with over 1300 references The analysis of the protein content of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including Multiple Sclerosis and Encephalitis. This book is a complete revision of the first edition published 16 years ago and reflects the advances in the field in that period. Containing the most comprehensive reference list available today with over 1300 references cross-indexed according to topics, it also includes many classical works that cannot be easily found through the public literature database (like PubMed). This book covers new areas of research such as the use of the analysis of protein content in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes).

With many new or completely revised illustrations, this book serves as not only a reference on the topic, but also a lab manual for bench work with recipes, and a clinical reference on individual diseases.

* Introduces the Eastern blotting, the technique considered the "gold standard" by the US Food & Drug Administration (FDA) for the demonstration of IgG by immunofixation following isoelectric focusing
* Provides numerous tables for ease-of-use
* Extensively cross-referenced with over 1300 references "The analysis of the proteins of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including multiple sclerosis and encephalitis. This book is a complete revision of the first edition published 16 years ago and reflects the advances in the field over that period." "The book contains the most comprehensive reference list available today with over 1300 references cross-indexed according to topics. Many classical works are included that cannot be easily found through public literature databases (like PubMed). Many illustrations are new or completely revised." "Many new areas of research are covered in this updated text, including the analysis of proteins in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes)."--BOOK JACKET