فیزیک پروتئین: دوره‌ای از سخنرانی‌ها (سری مواد نرم متراکم، سیالات پیچیده و بیومواد)

Protein Physics is a lively presentation of the most general problems of protein structure, folding and function from the physics and chemistry perspective, based on lectures given by the authors. It deals with fibrous, membrane and, most of all, with the best studied water-soluble globular proteins, in both their native and denatured states. The major aspects of protein physics are covered systematically, physico-chemical properties of polypeptide chains; their secondary structures; tertiary structures of proteins and their classification; conformational transitions in protein molecules and their folding; intermediates of protein folding; folding nuclei; physical backgrounds of coding the protein structures by their amino acid sequences and protein functions in relation to the protein structure. The book will be of interest to undergraduate and graduate level students and researchers of biophysics, biochemistry, biology and material science. * Designed for a wide audience of undergraduate and graduate students, as well as being a reference for researchers in academia and industry * Covers the most general problems of protein structure, folding, and function and introduces the key concepts and theories * Deals with fibrous, membrane and especially water-soluble globular proteins, in both their native and denatured states * Summarizes and presents in a systematic form the results of several decades of world wide fundamental research on protein physics, structure and folding * Examines experimental data on protein structure in the post-genome era Protein Physics is a lively presentation of the most general problems of protein structure, folding and function from the physics and chemistry perspective, based on lectures given by the authors. It deals with fibrous, membrane and, most of all, with the best studied water-soluble globular proteins, in both their native and denatured states. The major aspects of protein physics are covered systematically, physico-chemical properties of polypeptide chains; their secondary structures; tertiary structures of proteins and their classification; conformational transitions in protein molecules and their folding; intermediates of protein folding; folding nuclei; physical backgrounds of coding the protein structures by their amino acid sequences and protein functions in relation to the protein structure. The book will be of interest to undergraduate and graduate level students and researchers of biophysics, biochemistry, biology and material science.

* Designed for a wide audience of undergraduate and graduate students, as well as being a reference for researchers in academia and industry
* Covers the most general problems of protein structure, folding, and function and introduces the key concepts and theories
* Deals with fibrous, membrane and especially water-soluble globular proteins, in both their native and denatured states
* Summarizes and presents in a systematic form the results of several decades of world wide fundamental research on protein physics, structure and folding
* Examines experimental data on protein structure in the post-genome era Front Cover......Page 1 Protein Physics: A Course of Lectures......Page 4 Copyright Page......Page 5 CONTENTS......Page 6 Preface......Page 14 Foreword......Page 18 Acknowledgments......Page 20 Part I: INTRODUCTION......Page 22 Lecture 1......Page 24 Part II: ELEMENTARY INTERACTIONS IN AND AROUND PROTEINS......Page 34 Lecture 2......Page 36 Lecture 3......Page 44 Lecture 4......Page 54 Lecture 5......Page 64 Lecture 6......Page 78 Part III: SECONDARY STRUCTURES OF POLYPEPTIDE CHAINS......Page 94 Lecture 7......Page 96 Lecture 8......Page 106 Lecture 9......Page 124 Lecture 10......Page 138 Part IV: PROTEIN STRUCTURES......Page 146 Lecture 11......Page 148 Lecture 12......Page 156 Lecture 13......Page 166 Lecture 14......Page 182 Lecture 15......Page 196 Lecture 16......Page 210 Part V: COOPERATIVE TRANSITIONS IN PROTEIN MOLECULES......Page 226 Lecture 17......Page 228 Lecture 18......Page 248 Lecture 19......Page 260 Lecture 20......Page 272 Lecture 21......Page 284 Part VI: PREDICTION AND DESIGN OF PROTEIN STRUCTURE......Page 300 Lecture 22......Page 302 Lecture 23......Page 318 Part VII: PHYSICAL BACKGROUND OF PROTEIN FUNCTIONS......Page 332 Lecture 24......Page 334 Lecture 25......Page 352 Afterword......Page 366 Recommended reading......Page 368 Index......Page 370 "Covers the most general problems of protein structure, folding and function and introduces the concepts and theories. It deals with fibrous, membrane and especially water-soluble globular proteins, in both their native and denatured states. The book summarizes and presents in a systematic way the results of several decades of worldwide fundamental research on protein physics, structure and folding"--Back cover