Protein phosphorylation in control mechanisms: proceedings of the Miami Winter Symposia, January 15-16, 1973

Protein Phosphorylation in Control Mechanisms contains the proceedings of the Miami Winter Symposia entitled''Protein Phosphorylation in Control Mechanisms,''held on January 15-16, 1973, in Miami, Florida, and organized by the Department of Biochemistry at the University of Miami School of Medicine. The papers explore the role of protein phosphorylation in control mechanisms, including muscle metabolism and function, cell division, and histone and protamine binding to DNA. This volume is comprised of 28 chapters and begins with an overview of Earl W. Sutherland's scientific work and the involvement of cyclic AMP in enzyme inductions. The discussion then turns to the regulation of muscle metabolism and function by protein phosphorylation; the link between hormonally regulated enzymes in adipose tissue and cyclic AMP-dependent protein kinase; and regulation of the mammalian pyruvate dehydrogenase complex by phosphorylation and dephosphorylation. Subsequent chapters focus on the role of histone phosphorylation in cell division; histone phosphorylation and regulation of nuclear function; and protein phosphorylation in retinal photoreceptors. The final chapter is devoted to acetylation of nuclear proteins in rat testis. This book should be a valuable resource for biochemists. Content: MIAMI WINTER SYMPOSIA , Page ii Front Matter , Page iii Copyright , Page iv SPEAKERS, CHAIRMEN, AND DISCUSSANTS , Pages ix-xii PREFACE , Pages xiii-xiv , F. Huijing, E.Y.C. Lee THE FOURTH FEODOR LYNEN LECTURE: My Life and Cyclic AMP , Pages 1-30 , Earl W. Sutherland, Charles R. Park THE REGULATION OF MUSCLE METABOLISM AND FUNCTION BY PROTEIN PHOSPHORYLATION , Pages 31-45 , E.G. KREBS, J.T. STULL, P.J. ENGLAND, T.S. HUANG, C.O. BROSTROM, J.R. VANDENHEEDE HORMONALLY REGULATED ENZYMES IN ADIPOSE TISSUE LINKED TO CYCLIC AMP-DEPENDENT PROTEIN KINASE , Pages 47-65 , D. STEINBERG MOLECULAR CHARACTERIZATION OF CYCLIC AMP-DEPENDENT PROTEIN KINASES DERIVED FROM BOVINE HEART AND HUMAN ERYTHROCYTES , Pages 67-82 , O.M. ROSEN, C.S. RUBIN, J. ERLICHMAN REGULATION OF THE MAMMALIAN PYRUVATE DEHYDROGENASE COMPLEX BY PHOSPHORYLATION AND DEPHOSPHORYLATION , Pages 83-97 , L.J. REED, F.H. PETTIT, T.E. ROCHE, P.J. BUTTERWORTH CYCLIC AMP-DEPENDENT PROTEIN KINASES FROM RABBIT RED BLOOD CELLS: ACTIVATION, FUNCTION, AND MOLECULAR FORMS , Pages 99-121 , MARIANO TAO, RAJ KUMAR, PATRICIA HACKETT PROTEIN KINASE IN THE BOVINE CORPUS LUTEUM , Pages 123-144 , S. GOLDSTEIN, J.M. MARSH CYCLIC NUCLEOTIDES, PROTEIN PHOSPHORYLATION AND THE REGULATION OF FUNCTION IN NERVOUS TISSUE , Pages 145-174 , P. GREENGARD STUDIES OF THE cAMP RECEPTOR PROTEIN AND OF THE cAMP DEPENDENT PHOSPHORYLATION OF RIBOSOMAL PROTEIN , Pages 175-197 , G.N. GILL, G.M. WALTON, K.E. HOLDY, C.N. MARIASH, J.B. KALSTROM PHOSPHORYLATION OF RNA POLYMERASE IN E . COLI AND RAT LIVER , Pages 199-216 , O.J. MARTELO PHOSPHORYLATION OF NUCLEAR PROTEINS AT TIMES OF GENE ACTIVATION , Pages 217-249 , V.G. ALLFREY, E.M. JOHNSON, J. KARN, G. VIDALI THE ROLE OF HISTONE PHOSPHORYLATION IN CELL DIVISION , Pages 251-277 , ROGER CHALKLEY, ROD BALHORN, DENIS OLIVER, DARYL GRANNER THE ROLE OF ENZYMIC MODIFICATION IN THE CONTROL OF HISTONE AND PROTAMINE BINDING TO DNA , Pages 279-285 , G.H. Dixon, E.P.M. Candido, A.J. Louie HISTONE PHOSPHORYLATION AND REGULATION OF NUCLEAR FUNCTION , Pages 287-292 , Thomas A. Langan IDENTIFICATION OF THE FI-HISTONE PHOSPHOKINASE OF MITOTIC CHINESE HAMSTER CELLS , Page 295 , Robert S. Lake THE INDEPENDENCE OF HISTONE PHOSPHORYLATION FROM DNA SYNTHESIS , Page 297 , Lawrence R. Gurley, Ronald A. Walters, Robert A. Tobey IN VITRO PHOSPHORYLATION BY ATP AND GTP OF VINBLASTINE-ISOLATED MICROTUBULES FROM CHICK EMBRYO MUSCLES , Page 299 , M.M. Piras, R. Piras ADENOSINE 3′:5′-CYCLIC MONOPHOSPHATE MEDIATED CORTISOL INDUCTION OF HeLa ALKALINE PHOSPHATASE. , Page 301 , M.J. Griffin, G.H. Price, S. Tu CYCLIC AMP ACTIVATED PROTEIN KINASE OF KIDNEY MEMBRANES , Page 303 , Leonard R. Forte, Keith H. Byington CYCLIC NUCLEOSIDE PHOSPHATE DEPENDENT PROTEIN KINASE IN SEA URCHIN GAMETES AND EMBRYOS , Page 305 , M.Y.W. Lee, R.M. Iverson PROTEIN PHOSPHORYLATION IN RETINAL PHOTORECEPTORS , Page 307 , Richard G. Pannbacker cAMP DEPENDENT PROTEIN KINASE-CATALYZED PHOSPHORYLATION OF CARDIAC MICROSOMES , Page 309 , M.A. Kirchberger, M. Tada, S. Yoshioka, A.M. Katz. SUBSTRATE-SPECIFIC PHOSPHORYLATION OF RIBOSOMAL PROTEINS FROM RABBIT RETICULOCYTES , Page 311 , J.A. Traugh, M. Mumby, R.R. Traut A NOVEL, CYCLIC NUCLEOTIDE-DEPENDENT, PROTEIN KINASE FROM HUMAN POLYMORPHONUCLEAR LEUCOCYTES , Page 313 , P.-K. Tsung, N. Hermina, G. Weissmann HISTONE PHOSPHORYLATION IN NORMAL AND REGENERATING RAT LIVER , Page 315 , R.E. Branson, J.L. Irvin CYCLIC AMP AND GROWTH CONTROL IN BHK CELLS TRANSFORMED BY THE POLYOMA VIRUS MUTANT TS-3 , Page 317 , Wilfried E. Seifert IDENTIFICATION OF THE CYCLIC AMP BINDING PROTEIN IN HUMAN ERYTHROCYTE GHOSTS BY COVALENT INCORPORATION OF A DIAZOMALONYL DERIVATIVE OF CYCLIC [ 3 H] AMP , Page 319 , C.E. Guthrow, D.J. Brunswick Jr., B.S. Cooperman, H. Rasmussen ACETYLATION OF RAT TESTIS NUCLEAR PROTEINS , Page 321 , S.R. Grimes, J.L. Irvin, C.B. Chae