Proteases in the Brain (Proteases in Biology and Disease Book 3)

In all organs of the body proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer’s, Parkinson’s and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumour progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes. Proteases in the Brain reviews the role and regulation of proteases in Alzheimer’s disease brain ischemia and traumatic brain injury human glioma inflammatory and infectious diseases of the central nervous system metabolism of the prion protein modulating synaptic activity multiple sclerosis neuronal plasticity and memory consolidation Parkinson’s disease processing, conversion and inactivation of neuropeptides. Proteases in the Brain is a timely and useful source of information both for those well versed in the role of proteases in the brain and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction.

in All Organs Of The Body Proteases Have Critical Roles To Play Both In Normal Development And Functioning And In Disease States. The Brain Is No Exception To This, With Proteases Having Emerging Roles In Synaptic Plasticity, Memory, Neurodegenerative Disorders Such As Alzheimer’s, Parkinson’s And Prion Diseases, Ischemia And Traumatic Brain Injury, Inflammatory And Infectious Diseases, And Tumour Progression. Proteases In The Brain Brings Together A Wide Range Of Topics Under This Central Theme And Highlights The Large Number Of Proteases Involved In These Normal And Disease Processes.

proteases In The Brain Reviews The Role And Regulation Of Proteases In

alzheimer’s Disease

brain Ischemia And Traumatic Brain Injury

human Glioma

inflammatory And Infectious Diseases Of The Central Nervous System

metabolism Of The Prion Protein

modulating Synaptic Activity

multiple Sclerosis

neuronal Plasticity And Memory Consolidation

parkinson’s Disease

processing, Conversion And Inactivation Of Neuropeptides.

proteases In The Brain Is A Timely And Useful Source Of Information Both For Those Well Versed In The Role Of Proteases In The Brain And For Those Who Are Beginning To Realize The Important Role Of This Family Of Enzymes In Brain Function And Dysfunction.

Proteases and Alzheimer’s Disease: Present Knowledge and Emerging Concepts of Therapy....Pages 1-23 Calpain Proteolysis and the Etiology of Parkinson’s Disease: An Emerging Hypothesis....Pages 25-61 Cysteine Proteases in Neuronal Death in Brain Ischemia....Pages 63-77 Proteases in Traumatic Brain Injury....Pages 79-108 Proteases in CNS Infection and Inflammation....Pages 109-137 Dipeptidyl Peptidase IV Regulates T Cell Function in CNS Inflammation....Pages 139-150 Role and Regulation of Proteases in Human Glioma....Pages 151-177 Proteases and Prion Diseases....Pages 179-202 Neuropeptide Processing....Pages 203-234 Proteases and Neuronal Plasticity....Pages 235-270 Serine Proteases and Neuronal Plasticity in vivo ....Pages 271-301 Proteases and Synaptic Activity....Pages 303-322 Role of Proteinase-Activated Receptors in Brain Function....Pages 323-350 Matrix Metalloproteinases and Neuroinflammation in Multiple Sclerosis....Pages 351-371 In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. This book presents a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes. "Proteases in the Brain is a timely and useful source of information both for those well versed in the role of proteases in the brain and for those who are beginning to realize the important role of this family of enzymes in brain function and dysfunction."--Jacket