Prostate Cancer: Biology, Genetics, and the New Therapeutics (Contemporary Cancer Research)

Front Matter....Pages i-xxi Front Matter....Pages 1-1 Xenograft Models of Human Prostate Cancer....Pages 3-31 The Pathology of Human Prostatic Atrophy and Inflammation....Pages 33-48 Tissue Microarrays in Prostate Cancer Research....Pages 49-62 Prostate (Cancer) Stem Cells....Pages 63-72 Cancer-Host Interactions....Pages 73-86 Androgen Receptor Function in Prostate Cancer Progression....Pages 87-105 Hedgehog Signaling in Development and Cancer....Pages 107-118 Cholesterol, Cell Signaling, and Prostate Cancer....Pages 119-137 Gene Therapy for Advanced Prostate Cancer....Pages 139-163 Role of Transforming Growth Factor-β in Immunotherapy of Prostate Cancer....Pages 165-174 Biology and Therapeutic Basis of Prostate Cancer Bone Metastasis....Pages 175-191 Molecular Imaging....Pages 193-229 Quantum Dot Nanotechnology for Prostate Cancer Research....Pages 231-244 Front Matter....Pages 245-245 Expression Profiling of Prostate Cancer Progression....Pages 247-267 Somatic Alterations in Prostate Cancer Progression....Pages 269-283 Linkage Studies of Prostate Cancer Families to Identify Susceptibility Genes....Pages 285-299 Somatic DNA Methylation Changes and Prostatic Carcinogenesis....Pages 301-315 Telomeres, Telomerase, Chromosome Stability, and Prostate Cancer....Pages 317-352 Front Matter....Pages 353-353 Racial Differences in Prostate Cancer Mortality....Pages 355-376 Radiotherapy for the Treatment of Locally Advanced Prostate Cancer....Pages 377-396 Front Matter....Pages 353-353 Recombinant Antibody Candidates for Treatment of Prostate Cancer....Pages 397-410 Differentiation Agents and Epigenomic Therapies....Pages 411-443 Taxane-Based Chemotherapy for Prostate Cancer....Pages 445-462 Co-Targeting Therapeutics for Hormone Refractory Prostate Cancer....Pages 463-473 Intercellular Targets of Prostate Cancer....Pages 475-486 Novel and Efficient Translational Clinical Trial Designs in Advanced Prostate Cancer....Pages 487-495 Back Matter....Pages 497-508

prostate Cancer: Biology, Genetics, And The New Therapeutics, Second Edition, Reviews New, Valuable Approaches To The Treatment Of Prostate Cancer In Men. The Latest Edition Contains New Material On Molecular Imaging, New Treatments For Prostate Cancer, Molecular Targets, Cell Signaling Pathways, Bioinformatics, And Pathogenomics. The Book Details The Latest Innovations And Advances In Prostate Cancer And May Be Used As A Rapid Reference Text For Readers.

the Volume Profiles The Latest Advances In Cancer Research And Treatment And Includes Profound Studies In Prostate Stem Cells, Cancer-host Interactions, Hedgehog Signaling In Development And Cancer, Cholesterol And Cell Signaling, Gene Therapy For Advanced Prostate Cancer, And Noninvasive Strategies Such As Molecular Imaging To Visualize Gene Expression. This New Edition Also Investigates Expression Profiling And Somatic Alterations In Prostate Cancer Progression And Linkage Studies Of Prostate Cancer Families To Identify Susceptibility Genes. The Issues Of Racial Differences In Prostate Cancer Mortality, Radiotherapy For The Treatment Of Locally Advanced Prostate Cancer, Recombinant Antibody Candidates For Treatment, Taxane-based Chemotherapy, Lethal Phenotypes, And Novel And Efficient Translation Clinical Trials Are Also Presented In Great Depth.

prostate Cancer: Biology, Genetics, And The New Therapeutics, Second Edition, Provides Readers With A General Reference For Prostate Cancer From Prevention To Therapy And Will Be Of Value To Clinicians, Scientists, And Administrators Who Strive To Solve The Cancer Problem.

doody Review Services

reviewer:chung Lee, Ph.d.(northwestern University Feinberg School Of Medicine)
description:this Book Relates The Latest Knowledge And Technology In Translational Research In Prostate Cancer.
purpose:it Is A Valuable Reference And Guide For Any One Working In Translational Prostate Cancer Research - And It Is Easy To Read.
audience:this Is A Must Read For Those Who Are About To Enter The Field Of Translational Research In Prostate Cancer, But It Also Serves As An Excellent Reference For Established Investigators.
features:the 26 Chapters Are Divided Into Three Parts: Basic Biology And Imaging, Genetics, And Therapy. In Part I, 13 Chapters Cover Topics Ranging From Prostate Cancer Stem Cells To Bone Metastasis And From Androgen Receptor Functions To Novel Molecular Signaling Events. Of Particular Interest, The Editors Have Selected Practical Technologies Such As Xenograft Models, Tissue Microarrays, Nanotechnologies, And Modern Noninvasive Imaging Techniques. As Pointed Out By The Editors, In The Post-human-genome Era, Much Progress Has Been Made In Understanding The Genetics Of Human Prostate Cancer. The Five Chapters In Part Ii Offer Readers The Latest Information In Genetic And Epigenetic Advances In This Area. Part Iii Devotes Eight Chapters To The Most Innovative Ideas For Treating Patients With Advanced Prostate Cancer. Although Effective Therapeutic Strategies Are Not Yet Available For Advanced Prostate Cancer, The Lance Armstrong Effect Described By Don Coffey In The Foreword Fits Perfectly For This Book.
assessment:it Will Be Interesting To Look Back, Say In 10 Years, To See Whether These Chapters Have Paved The Way For The Development Of New And Efficacious Therapeutic Procedures For Prostate Cancer.