Prolactinomas : an interdisciplinary approach : Proceedings of the International Symposium on Prolactinomas Graz (Austria), April 29 - May 2, 1984

This monograph represents an expansion and deepening of previous works by Ole J. Benedictow - the author of highly esteemed monographs and articles on the history of plague epidemics and historical demography. In the form of a collection of articles, the author presents an in-depth monographic study on the history of plague epidemics in Scandinavian countries and on controversies of the microbiological and epidemiological fundamentals of plague epidemics. I Morphology Structure and ultrastructure of prolactinomas Prolactinomas and mixed adenomas with prolactin cells: an immunohistochemical study of the subcellular localization of hormones Immunocytochemical, chemical and nuclear-DNA studies of pituitary tumours Hyperplasia of prolactin pituitary cells with or without microadenoma Hormone-secretion in cell culture of microprolactinomas, periadenomatous tissue and capsules Immunocytochemical ultrastructural and culture characteristics of prolactin-secreting pituitary adenomas Immunohistochemical hormone determinations in pituitary adenomas in comparison with endocrinological findings in vivo New immunocytochemical observations in prolactinomas Problematic divergencies between clinical and immunocytochemical findings in prolactinomas Necrosis of prolactinoma cells after bromocriptine treatment Spontaneous pituitary lesions and plasma prolactin levels in rats II Radiology CT-findings in pituitary adenomas Comparative study of normal subjects and cases with microadenoma on high-resolution computed tomography III Endocrinological and clinical aspects Actions of dopamine receptor agonists at the pituitary level Dopamine and prolactinomas Rhythmometric study of the circadian profile of plasma prolactin in patients with prolactinoma or empty sella syndrome Prolactin responses to thyrotropin-releasing hormone, metoclopramide and insulin- induced hypoglycaemia in hyperprolactinaemic and normoprolactinaemic patients Evidence for functional impairment of growth hormone secretion in prolactinoma THS response to dopamine receptor blockade in women with PRL-secreting microadenoma: long lasting effect of surgical removal Prolactin and TSH responses to TRH and domperidone in delayed puberty Anterior pituitary function in patients with prolactinomas Pituitary adenomas with hyperprolactinaemia in males Prolactinoma in multiple endocrine neoplasia type I Recurrence of hyperprolactinaemia detected in long-term follow-up of surgically normalised microprolactinomas Impairment of pituitary hormone secretion in patients with prolactinoma IV Surgical treatment The recurrence of pituitary adenoma — a management challenge Transsphenoidal operations for prolactinomas Prolactinomas: surgical results in 96 cases Effect of transsphenoidal surgery on pituitary function Transsphenoidal microsurgical treatment of 77 prolactinomas Review of 56 prolactin-secreting pituitary adenomas The effect of transsphenoidal selective microadenomectomy on patients with prolactinomas Surgical results and long-term follow-up in female and male prolactinomas Otoliquorrhoea in large prolactinomas. Pathomechanism and surgical management Invasive prolactinomas in adolescents Residual anterior pituitary function following transsphenoidal resection of pituitary macroadenomas Long-term follow-up of prolactinomas. Clinical and morphologic correlation Clinicopathological and neurosurgical comparative analysis of operated recurrent prolactinomas and non-secreting chromophobe pituitary adenomas V Pharmacotherapy New aspects of medical treatment of prolactinomas Conservative management of prolactinoma Effect of bromocriptine therapy on large prolactinomas Macroprolactinomas in male patients: efficiency of treatment with a new dopaminergic drug (CU 32-085-Sandoz), tumor calcification and relative significance of preoperative tumour volume regression as estimated by CT-scan Evidence for spontaneous tumour shrinkage in a 45-year-old patient with a 20-year history of untreated microprolactinoma The influence of various forms of treatment on serum levels of prolactin, growth hormone and insulin-like growth factors I and II in patients with hyperprolactinaemia and acromegaly Persisting partial suppression of growth hormone excess in acromegaly after long-term treatment with bromocriptine Medical and surgical treatment of micro- and macroprolactinomas: seven years followup of 65 cases VI Aspects of gynecology and obstetrics Management of prolactinomas in pregnancy Long-term follow-up of hyperprolactinaemia in women Prophylactic bromocriptine treatment during pregnancy of women with macroprolactinomas: report of thirteen pregnancies Natural regression after pregnancy of a CT visualized microprolactinoma Prolactin levels and ovarian function after surgical treatment of prolactinomas Pregnancies after treatment of prolactinomas — course and complications Psychosomatic findings in patients with elevated prolactin List of contributors Authors’ index Subject index