Progress in the Chemistry of Organic Natural Products Vol. 94 (Progress in the Chemistry of Organic Natural Products, 94)

The three reviews cover the advances in the chemistry and biology of withanolides over the last 16 years, review the chemistry and biology of the rocaglamide-type derivatives and related compounds, with emphasis on their structural diversity, biosynthesis, pharmacological significance and total synthesis, and summarize the extensive chemistry and biology studies on a natural product, which have resulted in a novel therapy approved worldwide. Front Matter....Pages i-xviii Chemistry and Biology of Rocaglamides (= Flavaglines) and Related Derivatives from Aglaia Species (Meliaceae)....Pages 1-58 Chemistry of the Immunomodulatory Macrolide Ascomycin and Related Analogues....Pages 59-126 Withanolides and Related Steroids....Pages 127-229 Back Matter....Pages 231-253 Includes the three reviews that cover the advances in the chemistry and biology of withanolides, and review the chemistry and biology of the rocaglamide-type derivatives and related compounds, with emphasis on their structural diversity, biosynthesis, pharmacological significance and total synthesis.