پروفایل‌های مواد دارویی، مواد افزودنی و روش‌های مرتبط، جلد ۳۲

Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism. Read more... Abstract: Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism Content: Series Editors Page ii Contents Pages v-vii Contributors Page ix Preface Page xi Miconazole Nitrate: Comprehensive Profile Review Article Pages 3-65 Abdullah A. Al‐Badr Niclosamide: Comprehensive Profile Review Article Pages 67-96 Badraddin M.H. Al‐Hadiya Oxytetracycline: Analytical Profile Review Article Pages 97-117 Mochammad Yuwono, Gunawan Indrayanto Penicillamine: Physical Profile Review Article Pages 119-130 Abdulrahman Al‐Majed, Fathallah Belal, Saeed Julkhuf, Hussein El‐Subbagh Penicillamine: Analytical Profile Review Article Pages 131-148 Abdulrahman Al‐Majed, Fathallah Belal, Saeed Julkhuf Penicillamine: Adsorption, Distribution, Metabolism, and Elimination Profile Review Article Pages 149-152 Abdulrahman Al‐Majed, Fathallah Belal, Saeed Julkhuf Primaquine Diphosphate: Comprehensive Profile Review Article Pages 153-208 Abdullah A. Al‐Badr Valproic Acid and Sodium Valproate: Comprehensive Profile Review Article Pages 209-240 Ibrahim A. Alsarra, M. Al‐Omar, F. Belal Validation of Chromatographic Methods of Analysis Review Article Pages 243-259 Mochammad Yuwono, Gunawan Indrayanto Polymorphism and Solvatomorphism 2004 Review Article Pages 263-283 Harry G. Brittain Cumulative Index Pages 285-289 Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions are now augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change meets the needs of the pharmaceutical community and allows the development of a timely vehicle for publishing review materials on this topic. While offering comprehensive and specialised chapters, Profiles of Drug Substances, Excipients and Related Methodology, Volume 32 also presents a methodology review article on the validation of chromatographic methods of analysis, as well as a summary of the publications in 2004 that dealt with polymorphism and solvatomorphism. * Presents comprehensive reviews covering all aspects of drug development and formulation of drugs* Now encompassing critical review chapters* Meets the information needs of the drug development community