Production of Plant Derived Natural Compounds through Hairy Root Culture

This book provides the latest information about hairy root culture and its several applications, with special emphasis on potential of hairy roots for the production of bioactive compounds. Due to high growth rate as well as biochemical and genetic stability, it is possible to study the metabolic pathways related to production of bioactive compounds using hairy root culture. Chapters discuss the feasibility of hairy roots for plant derived natural compounds. Advantages and difficulties of hairy roots for up-scaling studies in bioreactors are included as well as successful examples of hairy root culture of plant species producing bioactive compounds used in food, flavors and pharmaceutical industry. This book is a valuable resource for researchers and students working on the area of plant natural products, phytochemistry, plant tissue culture, medicines, and drug discovery. Front Matter ....Pages i-xvii The Agrobacterium rhizogenes GALLS Gene Provides an Alternative Method to Transform Plants (Walt Ream, Wei Wei, Maciej Maselko, Larry Hodges)....Pages 1-15 Hairy Root Composite Plant Systems in Root-Microbe Interaction Research (Senthil Subramanian)....Pages 17-44 Production and Biosynthesis of Bioactive Stilbenoids in Hairy Root Cultures (Tianhong Yang, Lingling Fang, Fabricio Medina-Bolivar)....Pages 45-64 Hairy Root Cultures of Rhodiola rosea to Increase Valuable Bioactive Compounds (Henrik Lütken, Natalia Meropi-Antypa, Oliver Kemp, Josefine Nymark Hegelund, Renate Müller)....Pages 65-88 Production of Indole Alkaloids in Catharanthus roseus L. Hairy Root Cultures (Moemen S. Hanafy, Mohamed A. Matter, M. R. Rady)....Pages 89-116 Enhancement of Medicinally Important Bioactive Compounds in Hairy Root Cultures of Glycyrrhiza, Rauwolfia, and Solanum Through In Vitro Stress Application (Mrinalini Srivastava, Pratibha Misra)....Pages 117-132 An Efficient Hairy Root System for Withanolide Production in Withania somnifera (L.) Dunal (Appakan Shajahan, Chandrasekaran Thilip, Kunnampalli Faizal, Valiyaparambath Musfir Mehaboob, Palusamy Raja, Abubakker Aslam et al.)....Pages 133-143 Hairy Root Culture of Nicotiana tabacum (Tobacco) as a Platform for Gene Manipulation of Secondary Metabolism (Mahesh Kumar, Adinpunya Mitra)....Pages 145-163 Synthesis of Benzylisoquinoline Alkaloids and Other Tyrosine-Derived Metabolites in Hairy Root Cultures (Felipe Vázquez-Flota, María de Lourdes Miranda-Ham, Lizbeth Castro-Concha, Yahaira Tamayo-Ordoñez)....Pages 165-182 Mass Production of Transformed Hairy Root for Secondary Metabolites: A Case Study of Panax ginseng Hairy Roots (Gwi-Taek Jeong, Don-Hee Park)....Pages 183-201 Production of Ginsenosides by Hairy Root Cultures of Panax ginseng (Hosakatte Niranjana Murthy, So Young Park, Kee Yoeup Paek)....Pages 203-216 Chapter 10: Mass Production of Transformed Hairy Root for Secondary Metabolites: A Case Study of Panax ginseng Hairy Roots Chapter 1: The Agrobacterium rhizogenes GALLS Gene Provides an Alternative Method to Transform Plants Chapter 3: Production and Biosynthesis of Bioactive Stilbenoids in Hairy Root Cultures Chapter 2: Hairy Root Composite Plant Systems in RootMicrobe Interaction Research