Probiotics and Child Gastrointestinal Health: Advances in Microbiology, Infectious Diseases and Public Health Volume 10 (Advances in Experimental Medicine and Biology Book 1125)

This book shows the huge impact the gut microbiota has on the gastrointestinal health of humans with a particular focus on children. It also highlights the potential use of probiotic microorganisms to protect or improve children’s gastrointestinal health. Humans are not single organisms: We are a multi-organism structure composed of ourselves and our microbiota, living in close symbiosis since birth and even before. The huge impact that the billons of microscopic cells living in our gut have on our gastrointestinal and systemic health cannot be overestimated. The enormous progress that has been made in the past decade in our still very incomplete understanding of the gut microbiota is opening the door to potential applications in human health that were simply unthinkable before. One of the most interesting aspects of this new scientific horizon is the fact that we may identify (or even create in the laboratory) and utilize many of these “friendly bacteria” to protect, or improve our health. Thus, strains of probiotic microorganisms are being identified and studied in a vast array of clinical scenarios. Among the most investigated areas for probiotics is the gastrointestinal health of children. The topics addressed in this book are spanning from the development of the gut microbiota in the fetus and newborn all the way to current and potential applications in disparate conditions such as necrotizing enterocolitis, or infectious, or inflammatory conditions affecting the child. The book is written in a rigorous, evidence based manner by an international group of outstanding experts in these fields and is aimed at pediatric gastroenterologists, pediatricians and physician scientists alike. Front Matter ....Pages i-viii Front Matter ....Pages 1-1 Shaping Microbiota During the First 1000 Days of Life (Marta Selma-Royo, Maria Tarrazó, Izaskun García-Mantrana, Carlos Gómez-Gallego, Seppo Salminen, Maria Carmen Collado)....Pages 3-24 Necrotizing Enterocolitis and the Preterm Infant Microbiome (Jillian R. Baranowski, Erika C. Claud)....Pages 25-36 Can Postbiotics Represent a New Strategy for NEC? (Fabio Mosca, Maria Lorella Gianni, Maria Rescigno)....Pages 37-45 Front Matter ....Pages 47-47 Preventing and Treating Colic (Flavia Indrio, Vanessa Nadia Dargenio, Paola Giordano, Ruggiero Francavilla)....Pages 49-56 Targeting Food Allergy with Probiotics (Lorella Paparo, Rita Nocerino, Carmen Di Scala, Giusy Della Gatta, Margherita Di Costanzo, Aniello Buono et al.)....Pages 57-68 Use of Probiotics to Prevent Celiac Disease and IBD in Pediatrics (Gloria Serena, Alessio Fasano)....Pages 69-81 Front Matter ....Pages 83-83 Fighting Fatty Liver Diseases with Nutritional Interventions, Probiotics, Symbiotics, and Fecal Microbiota Transplantation (FMT) (Valerio Nobili, Antonella Mosca, Tommaso Alterio, Sabrina Cardile, Lorenza Putignani)....Pages 85-100 Probiotics in the Treatment of Inflammatory Bowel Disease (Stefano Guandalini, Naire Sansotta)....Pages 101-107 Acute Infectious Diarrhea (Andrea Lo Vecchio, Vittoria Buccigrossi, Maria Cristina Fedele, Alfredo Guarino)....Pages 109-120 Probiotics in Functional Gastrointestinal Disorders (Iva Hojsak)....Pages 121-137 Clostridium difficile Colitis Prevention and Treatment (Meltem Dinleyici, Yvan Vandenplas)....Pages 139-146 Back Matter ....Pages 147-150 "This book shows the huge impact the gut microbiota has on the gastrointestinal health of humans with a particular focus on children. It also highlights the potential use of probiotic microorganisms to protect or improve children's gastrointestinal health. Humans are not single organisms: We are a multi-organism structure composed of ourselves and our microbiota, living in close symbiosis since birth and even before. The huge impact that the billons of microscopic cells living in our gut have on our gastrointestinal and systemic health cannot be overestimated. The enormous progress that has been made in the past decade in our still very incomplete understanding of the gut microbiota is opening the door to potential applications in human health that were simply unthinkable before. One of the most interesting aspects of this new scientific horizon is the fact that we may identify (or even create in the laboratory) and utilize many of these "friendly bacteria" to protect, or improve our health. Thus, strains of probiotic microorganisms are being identified and studied in a vast array of clinical scenarios. Among the most investigated areas for probiotics is the gastrointestinal health of children. The topics addressed in this book are spanning from the development of the gut microbiota in the fetus and newborn all the way to current and potential applications in disparate conditions such as necrotizing enterocolitis, or infectious, or inflammatory conditions affecting the child"--Publisher's description