Principles and Practice of Image-Guided Radiation Therapy of Lung Cancer (Imaging in Medical Diagnosis and Therapy)

This book gives a comprehensive overview on the use of image-guided radiation therapy (IGRT) in the treatment of lung cancer, covering step-by-step guidelines for clinical implementations, fundamental principles and key technical advances. It covers benefits and limitations of techniques as well as quality and safety issues related to IGRT practice. * Addresses imaging simulation, treatment planning, verification, and delivery * Discusses important quality assurance issues * Describes current methods using specialized machines and technologies **Jing Cai, PhD,** is an Associate Professor of Radiation Oncology at Duke University Medical Center. **Joe Y. Chang, MD, PhD,** is Professor in the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center in Houston. **Fang-Fang Yin, PhD,** is Chief of the Division of Radiation Physics, Professor of Radiation Oncology, and Director of the Medical Physics program at Duke University. Cover -- Half title -- Series page -- Title page -- Contents -- Series preface -- Preface -- Editors -- Contributors -- Part 1: Introduction -- Chapter 1: Overview of IGRT -- 1.1 Introduction -- 1.2 Goal of IGRT -- 1.3 Benifits of IGRT -- 1.3.1 Tighter margins -- 1.3.2 Target motion -- 1.3.3 Intrafractional adjustments -- 1.3.4 Interfractional adjustments -- 1.4 Process of IGRT -- 1.5 Summary -- References -- Chapter 2: History and future of IGRT in lung cancer -- 2.1 Introduction -- 2.2 CT simulation and 3D-CRT have revolutionized RT in lung cancer -- 2.3 4D-CT milestone of highly conformal RT in moving targets -- 2.4 Adaptive RT -- 2.5 MRI-guided RT -- 2.6 Cancer biological conformality:Individualized dose pairing based on quantitative functional and molecular imaging -- References -- Part 2: Principles of IGRT for lung cancer -- Chapter 3: Imaging simulation for lung cancer IGRT -- 3.1 Introduction -- 3.2 4D-CT -- 3.2.1 History of 4D-CT -- 3.2.2 4D-CT Image Acquisition -- 3.2.2.1 Helical 4D-CT -- 3.2.2.2 Cine 4D-CT -- 3.2.2.3 Comparison of helical 4D-CT and cine 4D-CT -- 3.2.3 4D-CT Image sorting -- 3.3 Motion management considerations -- 3.3.1 Free breathing -- 3.3.1.1 Internal target volume -- 3.3.1.2 Mid-inspiration -- 3.3.2 Breath-hold -- 3.3.2.1 Voluntary -- 3.3.2.2 Active breathing control -- 3.3.3 Abdominal compression -- 3.3.4 Respiratory gating -- 3.3.5 Tumor tracking -- 3.3.6 Respiratory surrogate -- 3.3.6.1 External surrogate -- 3.3.6.2 Internal surrogate -- 3.4 Immobilization -- 3.5 Summary -- References -- Chapter 4: Treatment planning -- 4.1 Introduction -- 4.2 Contouring/delineation of target volumes and critical structures -- 4.2.1 Target volumes -- 4.2.1.1 Gross tumor volume (GTV) -- 4.2.1.2 Clinical target volume (CTV) -- 4.2.1.3 Internal margin (IM) -- 4.2.1.4 Internal target volume (ITV) -- 4.2.1.5 Setup margin (SM) "This book gives a comprehensive overview on the use of image-guided radiation therapy (IGRT) in the treatment of lung cancer, covering step-by-step guidelines for clinical implementations, fundamental principles and key technical advances. It covers benefits and limitations of techniques as well as quality and safety issues related to IGRT practice. Addresses imaging simulation, treatment planning, verification, and deliveryDiscusses important quality assurance issuesDescribes current methods using specialized machines and technologies Jing Cai, PhD, is an Associate Professor of Radiation Oncology at Duke University Medical Center. Joe Y. Chang, MD, PhD, is Professor in the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center in Houston. Fang-Fang Yin, PhD, is Chief of the Division of Radiation Physics, Professor of Radiation Oncology, and Director of the Medical Physics program at Duke University."--Provided by publisher This book showcases Image-guided radiation therapy's (IGRT) impact on the treatment of lung cancer, covering step-by-step guidelines for clinical implementations, alongside the fundamental principles and main technical advances. It covers benefits and limitations of techniques as well as quality and safety issues related to IGRT practice.