Primer to the Immune Response: Academic Cell Update Edition

Written in the same engaging conversational style as the acclaimed first edition, Primer to The Immune Response, 2nd Edition is a fully updated and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction to immunology. The authors bring clarity and readability to their audience, offering a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subject’s fascinating appeal. The content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. The superbly drawn figures are now in full color, complemented by full color plates throughout the book. The text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights. At the end of each chapter, a self-test quiz allows students to monitor their mastery of major concepts, while a set of conceptual questions prompts them to extrapolate further and extend their critical thinking. Moreover, as part of the Academic Cell line of textbooks, Primer to The Immune Response, 2nd Edition contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles also form the basis of case studies that are found in the associated online study guide and are designed to reinforce clinical connections. Key Features Complete yet concise coverage of the basic and clinical principles of immunology Engaging conversational writing style that is to the point and very readable Over 200 clear, elegant color illustrations Comprehensive glossary and list of abbreviations Readership Undergraduate medical students and graduate students taking the following courses: Introduction to Immunology, Immunology, Clinical Immunology, Medical Immunology, Medical Microbiology, Microbiology and Immunology, and Immunology and Disease Content: Abbreviations, Page i Cover Image, Page ii Front Matter, Page iii Copyright, Page iv Online Study Guide, Page v Preface, Pages vii-viii The Academic Cell Approach, Page ix Introduction to the Online Study Guide, Page xi Biographies: Authors, Page xiii Contributors, Page xv Acknowledgments, Pages xvii-xviii Chapter 1 - Introduction to the Immune Response, Pages 3-20 Chapter 2 - Components of the Immune System, Pages 21-54 Chapter 3 - Innate Immunity, Pages 55-83 Chapter 4 - The B Cell Receptor: Proteins and Genes, Pages 85-110 Chapter 5 - B Cell Development, Activation and Effector Functions, Pages 111-142 Chapter 6 - The Major Histocompatibility Complex, Pages 143-159 Chapter 7 - Antigen Processing and Presentation, Pages 161-179 Chapter 8 - The T Cell Receptor: Proteins and Genes, Pages 181-196 Chapter 9 - T Cell Development, Activation and Effector Functions, Pages 197-226 Chapter 10 - Regulation of Immune Responses in the Periphery, Pages 227-246 Chapter 11 - NK, γδ T and NKT Cells, Pages 247-268 Chapter 12 - Mucosal and Cutaneous Immunity, Pages 269-292 Chapter 13 - Immunity to Infection, Pages 295-332 Chapter 14 - Vaccination, Pages 333-375 Chapter 15 - Immunodeficiency, Pages 377-421 Chapter 16 - Tumor Immunology, Pages 423-455 Chapter 17 - Transplantation, Pages 457-486 Chapter 18 - Immune Hypersensitivity, Pages 487-516 Chapter 19 - Autoimmune Diseases, Pages 517-552 Chapter 20 - Hematopoietic Cancers, Pages 553-585 Appendix A - Selected Landmark Discoveries in Immunology, Pages 587-588 Appendix B - Nobel Prizes Awarded for Work in Immunology, Pages 589-590 Appendix C - Comparative Immunology, Pages 591-595 Appendix D - Selected CD Markers, Pages 597-611 Appendix E - Cytokines, Chemokines and Receptors, Pages 613-619 Appendix F - Selected Immunological Techniques, Pages 621-640 Glossary, Pages 641-658 Index, Pages 659-674

Written in the same engaging conversational style as the acclaimed first edition, Primer to The Immune Response, 2nd Edition is a fully updated and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction to immunology. The authors bring clarity and readability to their audience, offering a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subject’s fascinating appeal.

The content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. The superbly drawn figures are now in full color, complemented by full color plates throughout the book. The text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights. At the end of each chapter, a self-test quiz allows students to monitor their mastery of major concepts, while a set of conceptual questions prompts them to extrapolate further and extend their critical thinking. Moreover, as part of the Academic Cell line of textbooks, Primer to The Immune Response, 2nd Edition contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles also form the basis of case studies that are found in the associated online study guide and are designed to reinforce clinical connections.

• Complete yet concise coverage of the basic and clinical principles of immunology
• Engaging conversational writing style that is to the point and very readable
• Over 200 clear, elegant color illustrations
• Comprehensive glossary and list of abbreviations

Written in the same engaging conversational style as the acclaimed first edition, Primer to The Immune Response, 2 nd Edition is a fully updated and invaluable resource for college and university students in life sciences, medicine and other health professions who need a concise but comprehensive introduction to immunology. The authors bring clarity and readability to their audience, offering a complete survey of the most fundamental concepts in basic and clinical immunology while conveying the subject’s fascinating appeal. The content of this new edition has been completely updated to include current information on all aspects of basic and clinical immunology. The superbly drawn figures are now in full color, complemented by full color plates throughout the book. The text is further enhanced by the inclusion of numerous tables, special topic boxes and brief notes that provide interesting insights. At the end of each chapter, a self-test quiz allows students to monitor their mastery of major concepts, while a set of conceptual questions prompts them to extrapolate further and extend their critical thinking. Moreover, as part of the Academic Cell line of textbooks, Primer to The Immune Response, 2 nd Edition contains research passages that shine a spotlight on current experimental work reported in Cell Press articles. These articles also form the basis of case studies that are found in the associated online study guide and are designed to reinforce clinical connections. Complete yet concise coverage of the basic and clinical principles of immunology Engaging conversational writing style that is to the point and very readable Over 200 clear, elegant color illustrations Comprehensive glossary and list of abbreviations Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology.
This book is written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating “Immunomovie” that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles.

• Over 200 elegant 2-4 color illustrations
• 36 full-color plates of basic and clinical items of interest
• Take-home message and “Did You Get It?” self-test quiz at the end of each chapter
• 6 Appendices that provide topic enrichment
• 60-minute “Immunomovie” illustrating the immune response to bacterial, viral and parasitic infections
• Companion website housing illustrations/plates and immunomovie Primer to the Immune Response effectively presents complex immunological concepts. The book is divided into two parts, which cover basic immunology and clinical immunology. Part I presents the history and nature of immune response, and it describes the general features of the innate and adaptive immune responses. This part also explores the components of the immune system such as the cells and tissues. It also illustrates the intracellular communication through signal induction, intercellular communication through cytokines, and the cellular movement in the immune system. Furthermore, this part discusses proteins and genes, the development, activation and effector functions of both B cells and T cells. Part II focuses on clinical immunology and covers immunity to infection caused by extracellular and intracellular bacteria, viruses, parasites and fungi. This part also describes different kinds of diseases, such as the Acquired Immunodeficiency Syndrome caused by the Human Immunodeficiency virus, tumors, autoimmune diseases, and hematopoietic cancers. This part also includes discussions on vaccination, transplantation, and different types of immune hypersensitivity. Primer to The Immune Response is an invaluable resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. This book is written in the same engaging conversational style as the published reference book The Immune Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Primer to The Immune Response is beautifully illustrated with over 200 superb figures and 36 full-color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Included with purchase of the book is website access to a captivating Immunomovie"? that truly brings the immune response to pathogens to life. This new and unique immunology textbook compactly but elegantly covers both basic and clinical principles. Now available with the most current and relevant research from Cell Press, Mak's Primer to the Immune Response, Academic Cell Update Edition, gives readers both the concepts and the applications students need to know to fully grasp Immunology. Mak introduces basic concepts and then follows with specific applications in research today. This book is further enhanced by its inclusion in the Academic Cell collaboration, providing it with links to current and recently published research.

• Now with an online study guide with the most current, relevant research from Cell Press
• Full supplements including test bank, powerpoint and online self quizzing
• Color illustrations enhance key topics and concepts

This book is a resource for college students, university undergraduates and students in medicine and other health professions who need a concise but complete and understandable introduction to immunology. Written in the same engaging conversational style as the published reference book The Immune Response: Basic and Clinical Principles and conveys the same fascinating appeal of immunology. The authors bring clarity, readability and continuity of voice to an audience that requires only a brief survey of the most fundamental concepts in basic and clinical immunology. Illustrated with over 200 superb figures and 36 full color plates, and further enhanced by the inclusion of 60 tables and 6 Appendices. Introduction to the immune response Components of the immune system Innate immunity The B cell receptor: proteins and genes B cell development, activation, and effector functions The major histocompatibility complex Antigen processing and presentation The T cell receptor: proteins and genes T cell development, activation, and effector functions Regulation of immune responses in the periphery NK, ãä T, and NKT cells Mucosal and cutaneous immunity Immunity to infection Vaccination HIV and acquired immunodeficiency syndrome Tumor immunology Transplantation Immune hypersensitivity Autoimmune diseases Hematopoietic cancers. Mak introduces basic concepts and then follows with specific applications in research today. This book is further enhanced by its inclusion in the Academic Cell collaboration, providing it with links to current and recently published research. Now with an online study guide with the most current, relevant research from Cell Press. Full supplements including test bank, powerpoint and online self quizzing. Color illustrations enhance key topics and concepts Suitable for college and university students in life sciences, medicine and other health professions who need an introduction to immunology, this book offers a survey of the fundamental concepts in basic and clinical immunology while conveying the subject's appeal. Offers both the concepts and the applications students need to know to fully grasp Immunology. This book introduces basic concepts and then follows with specific applications in research.