Pregnancy Hypertension : Proceedings of the First Congress of the International Society for the Study of Hypertension in Pregnancy, held at University College, Dublin, on 27-29 September 1978

Plasma catecholamines were estimated late in the second stage of labour and before fetal expulsion in three groups of pregnancies: I. Normal pregnancies at term. 2. Pregnancies complicated by severe pre-eclampsia, under medical control in hospital for 2-5 weeks and induced at 37-39 weeks of pregnancy. 3. Pregnancies complicated by severe pre-eclampsia went into labour at term with no previous control to their toxaemias. Plasma catecholamines were determined in the maternal and cord blood, late in the second stage of labour and within 12 hours after delivery. Plasma catecholamines showed a highly significant rise in the maternal blood collected during the second stage of labour, after delivery, and in the cord blood, in pregnancies complicated with severe pre-eclampsia with no previous control when compared to normal pregnancy. The figures for the medically controlled severe pre-eclampsia had also presented a significant rise when correlated with the normal pregnancy. We can say that the adrenal medulla shares in the stress phenomenon during labour. Such stress is worse in pre-eclamptic patients, particularly the uncontrolled pre-eclam psia. The fetal adrenal also shares in the stress phenomenon in pre-eclampsia. Content: Front Matter....Pages iii-xxi Inaugural Address....Pages 1-11 Front Matter....Pages 13-13 Immunological studies in severe gestosis....Pages 15-17 The HLA system and severe pre-eclampsia....Pages 19-27 Serum factors in severe pre-eclamptic toxaemia (PET)....Pages 29-36 Immune complexes in pre-eclampsia....Pages 37-40 Pre-eclampsia and changed paternity....Pages 41-44 The influence of coitus on immune response....Pages 45-48 Front Matter....Pages 49-49 A prospective serial study of plasma angiotensin I converting enzyme in pregnancy....Pages 51-58 A study of plasma renin activity in normotensive subjects with a previous history of pregnancy-associated hypertension....Pages 59-65 The effect of delivery on maternal and fetal plasma renin and dopamine-β-hydroxylase in hypertensive disease of pregnancy....Pages 67-73 The effect of a specific AII antagonist (Saralasin) on blood pressure in the immediate puerperium....Pages 75-80 Post-partum changes in the renin-angiotensin system....Pages 81-85 Relationship of angiotensin sensitivity to sodium excretion, renin-aldosterone axis and to progesterone in late pregnancy....Pages 87-91 Labetalol — a new α and β-adrenoreceptor blocking agent in pregnancy-induced-hypertension....Pages 93-98 The effect of epidural analgesia on the renin—angiotensin system in pregnancy hypertension....Pages 99-104 Front Matter....Pages 105-105 Circadian variation of blood-pressure in pregnancy....Pages 107-112 The roll-over test in healthy primagravid subjects....Pages 113-118 The lack of relationship between postural differences in blood pressure and pregnancy outcome....Pages 119-129 Mechanisms for blood-pressure changes in the roll-over test....Pages 131-142 Relationship between prolactin secretion and blood-pressure behaviour in late pregnancy....Pages 143-148 Front Matter....Pages 105-105 Serum DBH activity in term delivery and newborn....Pages 149-154 Ionic basis of vascular smooth muscle contraction....Pages 155-159 Plasma epinephrine and norepinephrine in normotensive and pregnancy-induced hypertensive pregnancies....Pages 161-166 Plasma catecholamines during labour in normal and pre-eclamptic pregnancies....Pages 167-173 Relation between plasma volume and uric acid in the development of hypertension in pregnancy....Pages 175-179 Modulation of vascular responsiveness to angiotensin II during human pregnancy....Pages 181-189 Evans blue disappearance rate in normal pregnancy and pre-eclampsia....Pages 191-195 Front Matter....Pages 197-197 Diameters of uteroplacental arteries....Pages 199-204 The ultrastructure of the placenta in maternal pre-eclampsia....Pages 205-211 Uteroplacental arteries and hypertensive pregnancy....Pages 213-219 Relevance of renal biopsy to the future course of pre-eclamptic women....Pages 221-230 Stereologic and autoradiographic studies on the human placenta. Relationship to hormonal status and hypertension in pregnancy....Pages 231-242 Data of placenta morphology in a prospective clinical study on hypertension in pregnancy....Pages 243-246 The development of a new method for monitoring the fetal placental circulation....Pages 247-254 Early endocrine investigation of placental function and preventive measures in pregnancy-induced hypertension....Pages 255-260 Plasma prolactin in pregnancy-induced hypertension....Pages 261-265 Assessment of uteroplacental haemodynamics in pre-eclampsia....Pages 267-270 Studies of uterine haemodynamics and the effects of ritodrine....Pages 271-275 Placental metabolism in pre-eclamptic toxaemia of pregnancy....Pages 277-292 The Newton’s iteration, a satisfying method to evaluate placenta perfusion curves....Pages 293-299 Front Matter....Pages 301-301 Renal handling of sodium and electrolytes in pre-eclamptic patients on strict bed-rest and in upright activity....Pages 303-306 The effect of hypertension and oedema on birth-weight....Pages 307-311 The value of laboratory assessment of the severity of pre-eclampsia....Pages 313-319 ‘Pre-hypertensive’ abnormalities of the intrarenal circulation following complicated pregnancies....Pages 321-327 The relation of renal disease and symptomatology in pregnancy....Pages 329-332 A biopsy study of hypertension in pregnancy....Pages 333-338 γ-Glutamyl transferase and β-microglobulin studies in pregnancy....Pages 339-342 Maternal and fetal aldosterone levels at delivery in normo- and hypertensive pregnancy....Pages 343-348 The frequency of asymptomatic significant bacteriuria in hypertensive pregnant women....Pages 349-353 Front Matter....Pages 355-355 Fibrinogen degradation products and factor VIII consumption in normal pregnancy and pre-eclampsia: role of the placenta....Pages 357-369 Sequential studies in pre-eclampsia using plasma fibrinogen chromatography....Pages 371-378 Soluble fibrinogen-fibrin complexes in pre-eclampsia....Pages 379-382 Factor VIII related antigen/factor VIII ratio and pre-kallikrein activity in monitoring the hypertensive diseases of pregnancy....Pages 383-391 Plasma fibrinogen in pregnancy....Pages 393-396 Abnormal platelet function in pre-eclampsia....Pages 397-404 Abnormalities of renal platelet localization and fibrinolysis following PAH: the value of prophylactic use of anticoagulants....Pages 405-411 Eclampsia and intravascular coagulation....Pages 413-417 Factor VII-related antigen and factor VIII coagulant activity in normal pregnancy, pre-eclampsia and abruptio placentae....Pages 419-425 Front Matter....Pages 427-427 Comparative immunology of human and baboon placenta....Pages 429-437 Analysis of blood-pressure control in normotensive and hypertensive animals with normal and reduced renal mass....Pages 439-444 Front Matter....Pages 427-427 Experimental toxaemia in the pregnant dog and the aetiology of toxaemia....Pages 445-457 Blood-pressure and blood-flow changes produced by pregnancy, indomethacin and angiotensin II....Pages 459-464 Front Matter....Pages 465-465 Propranolol in hypertension during pregnancy: ten cases....Pages 467-473 Mortality in eclampsia in relation to treatment modalities: a 10-year review....Pages 475-482 Is eclampsia preventable?....Pages 483-488 Prognostic significance of biochemical parameters in pre-eclampsia....Pages 489-495 Pregnancy-induced hypertension and proteinuria in diabetic and multiple pregnancy....Pages 497-500 Biochemical studies and delayed post-partum convulsion in Nigeria....Pages 501-509 Acute renal failure in pregnancy....Pages 511-515 Experience with diazoxide in the treatment of acute severe toxaemia of pregnancy....Pages 517-524 Pre-eclamptic toxaemia: a conservative approach to drug therapy....Pages 525-527 Clinical indices of perinatal problems related to hypertension in pregnancy....Pages 529-534 Hypertension in pregnancy and poor intra-uterine fetal growth....Pages 535-538 The influence of continuous epidural block on uteroplacental blood-flow....Pages 539-542 Swan-Ganz catheterization as a guide in therapy and an investigative aid in the management of severe pre-eclamptic toxaemia of pregnancy....Pages 543-548 Cigarette-smoking and pregnancy-induced hypertension....Pages 549-553 Epidural analgesia during labour in patients with severe pre-eclampsia....Pages 555-559 Cigarette-smoking and the fetus with special reference to blood-pressure levels....Pages 561-564 The influence of hypertension in pregnancy on the maternal serum alpha fetoprotein concentration....Pages 565-569 Some psychosomatic aspects of the hypertensions of pregnancy....Pages 571-575 Front Matter....Pages 465-465 Controlled study of subcutaneous heparin and dipyridamole in women at high risk to fetal growth retardation....Pages 577-580 Neurofibromatosis in pregnancy and hypertension....Pages 581-584 Recurrent pregnancy-induced hypertension successfully treated by heparin....Pages 585-588 Back Matter....Pages 589-597