Practical Medical and Surgical Management of Chronic Rhinosinusitis

This book is a comprehensive compendium on the medical and surgical treatment of chronic rhinosinusitis (CRS), with or without polyposis. Detailed coverage is provided of a wide range of topics, including medical and surgical management of CRS and its subsets, medical therapy in the pre- and postoperative period and specific medical therapeutic classes currently employed in CRS patients. Each chapter highlights key aspects of specific therapies, including mechanism of action, indications, dosages, side-effects and available clinical efficacy data and emphasizes practical management pearls and pitfalls. Operative techniques for endoscopic sinonasal procedures for CRS are also outlined. The book will be a valuable resource for practicing general otolaryngologists, rhinologists and allergists as well as residents and fellows in training. It will also serve as a reference guide for physician assistants, nurse practitioners and nurses involved in the care of CRS patients. Part I Overview of Chronic Rhinosinusitis 1 Epidemiology and Pathophysiology of Chronic Rhinosinusitis 3 Eric T. Carniol, Peter F. Svider, Alejandro V?zquez, and Jean Anderson Eloy 2 Microbiology of Chronic Rhinosinusitis 19 R. Peter Manes 3 Endoscopic Diagnosis of Chronic Rhinosinusitis 29 Joshua Wiedermann, Sean B. Bury, and Ameet Singh 4 Radiographic Diagnosis of Chronic Rhinosinusitis 43 Carrie E. Flanagan, Kristen L. Baugnon, and John M. DelGaudio 5 Classification of Chronic Rhinosinusitis and Its Subsets 73 Benjamin P. Hull and Joseph K. Han 6 Nasal Polyposis 111 Neville W.Y. Teo and Peter H. Hwang 7 Fungal Rhinosinusitis 131 Drew P. Plonk, Amber Luong, and Martin J. Citardi 8 Management of Functional Endoscopic Sinus Surgery (FESS) Failures 161 Ashleigh A. Halderman, Janalee Stokken, and Raj Sindwani 9 Pediatric Rhinosinusitis 177 Michael C. Kao and Sanjay R. Parikh 10 Allergic Rhinitis 191 Rachel Georgopoulos and Elina Toskala Part II Medical Therapy of Chronic Rhinosinusitis 11 Overview of the Medical Management of Chronic Rhinosinusitis 211 Dana L. Crosby and David W. Kennedy 12 Oral Antibiotics as Anti-infectives 225 Justin T. Casey, Todd T. Kingdom, and Anne E. Getz 13 Oral Antibiotics as Anti-inflammatories 237 C. Carrie Liu. Timothy L. Smith, and Luke Rudmik 14 Topical and Intravenous Antibiotics 253 John Craig and Parul Goyal 15 Oral Corticosteroids 267 David M. Poetker 16 Topical Steroids 277 Kevin C. Welch 17 Oral and Topical Antifungals 297 Wytske Fokkens and Vishal Pundir 18 Leukotriene Modifiers 305 Mark A. Zacharek and Andrew C. Birkeland 19 Aspirin Desensitization and High-Dose Aspirin Therapy in Aspirin-Exacerbated Respiratory Disease 313 Katherine N. Cahill, Kathleen Buchheit, Carolyn Word, and Larry Borish 20 Saline Irrigations 323 Niall Jefferson and Richard Harvey 21 Emerging Innovative Topical Therapies 339 Josh Meier and Eric H. Holbrook Part III Surgical Therapy of Chronic Rhinosinusitis 22 Endoscopic Sinus Surgery: Rationale, Indications, and Techniques 351 Marie Bussieres and Erin D. Wright 23 Medical Therapy in the Preoperative and Postoperative Period 369 Opeyemi O. Daramola and Rakesh K. Chandra 24 Surgery of the Maxillary Sinus 385 Jeremiah A. Alt and Richard R. Orlandi 25 Ethmoid Sinus Surgery 399 Andrew N. Goldberg and Chase M. Heaton 26 Surgery for Frontal Sinus Disease 411 Caitlin McLean, Nathan A. Deckard. and Pete S. Batra 27 Surgery for Sphenoid Sinus Disease 427 Stanley W. McClurg. Brian D. Thorp, and Brent A. Senior 28 Surgery for Nasal Polyposis 439 Joseph Brunworth and Peter John Wormald 29 Surgery for Allergic Fungal Rhinosinusitis 455 Jessica W. Grayson and Bradford A. Woodworth 30 Surgery for Pediatric Rhinosinusitis 469 Hassan H. Ramadan 31 Surgery of the Nasal Septum and Turbinates 483 Phillip S. LoSavio and Thomas R. OToole Index 509 Chronic rhinosinusitis (CRS) is an inflammatory disorder of the nose and paranasal sinuses with symptoms persisting for at least 3 months. The treatment paradigm for CRS includes medical therapy as the cornerstone, coupled with endoscopic sinus surgery in refractory cases. To date, however, no FDA-approved treatments exist for medical treatment of CRS, and most treatment algorithms rely on expert opinion supplemented by available peer-review data. This underscores the need for a comprehensive primer to optimize the care of CRS patients. This book is a detailed compendium on the medical and surgical treatment of CRS, with or without polyposis. Detailed coverage is provided of a wide range of topics, including pathophysiologic mechanisms, medical and surgical management of CRS and its subsets, medical therapy in the pre- and postoperative period, specific medical therapeutic classes currently employed in CRS patients, and optimization of the efficacy of endoscopic sinus surgery for postoperative medical therapy. Each chapter highlights key aspects of specific therapies, including mechanism of action, indications, dosages, side-effects, and available clinical efficacy data, and emphasizes practical management pearls and pitfalls from experts in the field. Operative techniques for endoscopic sinonasal procedures for CRS are also outlined. This book will be a valuable resource for practicing general otolaryngologists, rhinologists, and allergists as well as residents and fellows in training. It will also serve as a reference guide for physician assistants, nurse practitioners, and nurses involved in the care of CRS patients.--Résumé de l'éditeur Chronic rhinosinusitis (CRS) is an inflammatory disorder of the nose and paranasal sinuses with symptoms persisting for at least 3 months. The treatment paradigm for CRS includes medical therapy as the cornerstone, coupled with endoscopic sinus surgery in refractory cases. To date, however, no FDA-approved treatments exist for medical treatment of CRS, and most treatment algorithms rely on expert opinion supplemented by available peer-review data. This underscores the need for a comprehensive primer to optimize the care of CRS patients. ℗l This book is a detailed compendium on the medical and surgical treatment of CRS, with or without polyposis. Detailed coverage is provided of a wide range of topics, including pathophysiologic mechanisms, medical and surgical management of CRS and its subsets, medical therapy in the pre- and postoperative period, specific medical therapeutic classes currently employed in CRS patients, and optimization of the efficacy of endoscopic sinus surgery for postoperative medical therapy. Each chapter highlights key aspects of specific therapies, including mechanism of action, indications, dosages, side-effects, and available clinical efficacy data, and emphasizes practical management pearls and pitfalls from experts in the field. Operative techniques for endoscopic sinonasal procedures for CRS are also outlined.℗l ℗l This book will be a valuable resource for practicing general otolaryngologists, rhinologists, and allergists as well as residents and fellows in training. It will also serve as a reference guide for physician assistants, nurse practitioners, and nurses involved in the care of CRS patients