Practical Epilepsy

Written for busy practitioners and trainees, Practical Epilepsy is the only concise yet exhaustive reference encompassing the broad scope of clinical epilepsy. It contains core information for professionals who wish gain a breadth and depth of knowledge about epilepsy in a shorter amount of time than is required to read large reference books, and is a valuable review tool for self-assessment or exam preparation. Designed to be read cover-to-cover, this highly practical reference covers basic science, assessment, and treatment and uses clear, succinct narratives, lists, tables, and illustrations to present the essential information needed to understand all aspects of epilepsy. The first section of the book introduces the clinical aspects of the science of epileptology with chapters on pathophysiology, genetics, classification, syndromes, epidemiology, etiology, and differential diagnosis. The second section is devoted to diagnostic evaluation, including instrumentation, normal and abnormal EEG, ICU EEG monitoring, scalp and intracranial video EEG monitoring, brain mapping, seizure semiology, neuroimaging, and other techniques. Section three covers treatment with a thorough review of basic principles, all classes of antiepileptic drugs, stimulation therapy, surgery, and dietary and alternative therapies. The final section focuses on special situations and associated concerns, ranging from status epilepticus and psychogenic nonepileptic seizures to migraines and reproductive issues. Key Features: Delivers a concise yet thorough review of the clinical science and current practice of epilepsy medicine Chapter contributions come from a wide array of specialists Presents information in crisp, formatted chapters that distill must-know information for maximum utility Useful for practitioners at any level, from trainees to more experienced clinicians Illustrated with over 100 figures, including EEG readouts and other clinical images Serves as a valuable review tool for self-study or exam preparation About the Editor: Aatif M. Husain, MD, Professor, Department of Neurology, Duke University Medical Center, Durham, NC Écrit pour les praticiens occupés et les stagiaires, Pratical epilepsy est la seule référence encore exhaustive concise qui englobe la vaste portée de l'épilepsie clinique. Il contient des informations de base pour les professionnels qui souhaitent acquérir une ampleur et la profondeur des connaissances sur l'épilepsie dans un court laps de temps, nécessaire pour lire les grands ouvrages de référence, et est un outil d'évaluation utile pour l'auto-évaluation ou de la préparation de l'examen. Conçu pour être lu couverture à couverture, cette référence très pratique couvre la science fondamentale, l'évaluation et le traitement claires, des récits succincts, des listes, des tableaux et des illustrations pour présenter les informations essentielles nécessaires pour comprendre tous les aspects de l'épilepsie. La première partie du livre présente les aspects cliniques de la science de l'épileptologie avec des chapitres sur la physiopathologie, la génétique, la classification, les syndromes, l'épidémiologie, l'étiologie et le diagnostic différentiel. La deuxième section est consacrée à l'évaluation diagnostique, y compris l'instrumentation, normal et EEG anormal, la surveillance ICU EEG, le cuir chevelu et la vidéo intracrânienne EEG surveillance, la cartographie du cerveau, la saisie sémiologie, neuroimagerie, et d'autres techniques. La troisième section porte sur le traitement par un examen approfondi des principes de base, toutes les classes de médicaments antiépileptiques, thérapie de stimulation, la chirurgie et les traitements alimentaires et alternatives. La dernière section se concentre sur des situations particulières et les préoccupations connexes, allant de status epilepticus et des crises non épileptiques psychogènes aux migraines et les problèmes de reproduction. Caractéristiques principales:. * Rend un examen encore approfondi concis de la science clinique et la pratique actuelle de la médecine épilepsie * contributions Chapitre proviennent d'un large éventail de spécialistes * Presents informations nettes et chapitres formatés distillent doivent en connaître l'information pour une utilité maximale.. * Utile pour les praticiens à tous les niveaux, des stagiaires aux cliniciens plus expérimentés. * Illustré avec plus de 100 chiffres, y compris les lectures d'EEG et d'autres images cliniques. * Sert comme un outil d'évaluation utile pour l'auto-apprentissage ou de la préparation de l'examen "I believe this book is a trusted resource for any health care professional in daily practice dealing with patients with epilepsy. I highly recommend this book to practitioners at any level, from trainees to more experienced clinicians who are working on epilepsy... It may also serve as a valuable review tool for self-study and/or preparation for the Board certification and recertification examinations." --Jin Jun Luo, MD, PhD, Temple University, Neurological Cases Written for busy practitioners and trainees, Practical Epilepsy is the only concise yet exhaustive reference encompassing the broad scope of clinical epilepsy. It contains core information for professionals who wish to gain a breadth and depth of knowledge about epilepsy in a shorter amount of time than is required to read large reference books, and is a valuable review tool for self-assessment or exam preparation. Designed to be read cover-to-cover, this highly practical reference covers basic science, assessment, and treatment and uses clear, succinct narratives, lists, tables, and illustrations to present the essential information needed to understand all aspects of epilepsy. The first section of the book introduces the clinical aspects of the science of epileptology with chapters on pathophysiology, genetics, classification, syndromes, epidemiology, etiology, and differential diagnosis. The second section is devoted to diagnostic evaluation, including instrumentation, normal and abnormal EEG, ICU EEG monitoring, scalp and intracranial video EEG monitoring, brain mapping, seizure semiology, neuroimaging, and other techniques. Section three covers treatment with a thorough review of basic principles, all classes of antiepileptic drugs, stimulation therapy, surgery, and dietary and alternative therapies. The final section focuses on special situations and associated concerns, ranging from status epilepticus and psychogenic nonepileptic events to migraines and reproductive issues. Key Cover -- Title -- Copyright -- Contents -- Contributors -- Preface -- Share Practical Epilepsy -- Part I: Clinical Aspects -- Chapter 1: Pathophysiology -- Cellular Physiology -- Genetic Epilepsy -- Autoimmune Epilepsy -- Role of Astroglia in Epileptogenesis -- Mesial Temporal Sclerosis -- Pathophysiology of Primary Generalized Epilepsies -- Mechanism of Ictogenesis -- References -- Chapter 2: Genetics -- Overview of the Human Genome -- Overview of Discovery Genetics in Epilepsy -- Genetic Association Studies -- Copy Number Variations -- Large Structural Variants -- Next-Generation Sequencing Studies -- Pharmacogenomics -- Clinical Genetic Testing -- References -- Chapter 3: Epileptic Seizures -- Considerations in Classification -- The 1981 Recommendations for the Classification of Seizures -- The 2010 Recommendations for Classification of Seizures -- Common Use -- Illustrative Cases -- References -- Chapter 4: Epilepsy Syndromes -- Classification of Epileptic Syndromes and the Epilepsies -- Historical Overview -- Epilepsy Syndromes/Electroclinical Syndromes -- References -- Chapter 5: Neonatal Seizures -- Differential Diagnosis -- Epidemiology and Risk Factors -- Etiologies -- Diagnostic Evaluation -- Treatment of Neonatal Seizures -- References -- Chapter 6: Epidemiology -- Definitions -- Incidence and Prevalence -- Etiology -- Prognosis -- Mortality -- Status Epilepticus -- References -- Chapter 7: Etiology -- Risk Factors -- Etiologies -- References -- Chapter 8: Differential Diagnosis -- Clinical Presentation of Seizures -- Diagnosis -- References -- Part II: Diagnostic Evaluation -- Chapter 9: Clinical Evaluation -- History -- Examination -- Epilepsy-Related Health Screening -- Investigations -- EEG -- Diagnosis -- Evaluation of First Seizure -- Follow-Up Evaluations -- Patient Education -- Epilepsy Quality Measures -- References Using narrative text, lists, tables, and illustrations, this practical reference discusses all essential aspects of epilepsy. The book can be read cover-to-cover within a few weeks or months for those looking to develop an understanding and clinical appreciation of the field, from basic science to assessment to treatment.