Porous Silicon for Biomedical Applications (Woodhead Publishing Series in Biomaterials)

Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. __Porous Silicon for Biomedical Applications__ provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial. Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing, and explores the optical properties of porous silicon materials; in vivo imaging assessment and radiolabelling of porous silicon; and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumor targeting and imaging, and porous silicon scaffolds for functional tissue engineering, stem cell growth, and osteodifferentiation. With its acclaimed editor and international team of expert contributors, __Porous Silicon for Biomedical Applications__ is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in the field. Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.

Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.

With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies.

• Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applications
• Reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassembly
• Considers the challenges associated with implantable systems, including biocompatibility and sterilization

Provides an overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications. This title reviews the fundamentals of implantable systems before part two goes on to consider the challenges associated with their development and use. Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications. Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants. With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies

Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous Silicon for Biomedical Applications provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial.

Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing, and explores the optical properties of porous silicon materials; in vivo imaging assessment and radiolabelling of porous silicon; and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumor targeting and imaging, and porous silicon scaffolds for functional tissue engineering, stem cell growth, and osteodifferentiation.

With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in the field.

• Comprehensive review of porous silicon focusing on the fabrication and properties of this emerging material
• Specifically discusses drug delivery and orthopedic applications of porous silicon
• Aimed at materials researchers and scientists in the biomaterials industry – particularly those concerned with drug delivery and orthopedics

The on-going ‘green’ trend in the personal care industry coupled with global environmental concerns, place natural-origin, biodegradable and skin-friendly surfactants such as alkyl polyglucosides (APGs) in high demand. After successful use in cosmetics, sufficient data has been obtained to welcome some sugar emulsifiers into the field of drug dosage. Alkyl Polyglucosides presents a comprehensive compendium which guides a researcher from the APG-related preformulation stages to formulation processing, including the investigation of various APG-stabilized systems skin performance. This book introduces various APG representatives, their benefits in relation to certain conventional surfactants, physicochemical and interfacial properties, possible interaction with commonly used ingredients and diverse characterization techniques indispensable for the assessment of colloidal systems. The first chapter introduces alkyl polyglucosides, followed by chapters on their properties, behaviour, an overview of the patent protection mechanisms and guidelines for submitting patent applications. Finally, a conclusion surveys international patent applications involving APGs.

• introduces the field of alkyl polyglucoside emulsifiers, listing all the contemporary and newly synthesized APG emulsifiers
• provides detailed information on various aspects of APG-based structures
• reveals potential of APG-stabilized vehicles as prospective delivery systems using several model drugs and cosmetic actives
• includes an up-to-date review of research conducted in the field of APGs, facilitating future preformulation and formulation studies for researchers
• offers a concise and practical compendium of characterization techniques

Porous silicon has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous Silicon for Biomedical Applications provides a comprehensive review of this emerging nanostructured and biodegradable biomaterial. Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing, and explores the optical properties of porous silicon materials; in vivo imaging assessment and radiolabelling of porous silicon; and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumor targeting and imaging, and porous silicon scaffolds for functional tissue engineering, stem cell growth, and osteodifferentiation. With its acclaimed editor and international team of expert contributors, Porous Silicon for Biomedical Applications is a technical resource and indispensable guide for all those involved in the research, development, and application of porous silicon and other biomaterials, while providing a comprehensive introduction for students and academics interested in the field. Comprehensive review of porous silicon focusing on the fabrication and properties of this emerging material Specifically discusses drug delivery and orthopedic applications of porous silicon Aimed at materials researchers and scientists in the biomaterials industry – particularly those concerned with drug delivery and orthopedics The on-going 'green' trend in the personal care industry coupled with global environmental concerns, place natural-origin, biodegradable and skin-friendly surfactants such as alkyl polyglucosides (APGs) in high demand. After successful use in cosmetics, sufficient data has been obtained to welcome some sugar emulsifiers into the field of drug dosage. Alkyl Polyglucosides presents a comprehensive compendium which guides a researcher from the APG-related preformulation stages to formulation processing, including the investigation of various APG-stabilized systems skin performance. This book introduces various APG representatives, their benefits in relation to certain conventional surfactants, physicochemical and interfacial properties, possible interaction with commonly used ingredients and diverse characterization techniques indispensable for the assessment of colloidal systems. The first chapter introduces alkyl polyglucosides, followed by chapters on their properties, behaviour, an overview of the patent protection mechanisms and guidelines for submitting patent applications. Finally, a conclusion surveys international patent applications involving APGs. Introduces the field of alkyl polyglucoside emulsifiers, listing all the contemporary and newly synthesized APG emulsifiers Provides detailed information on various aspects of APG-based structures Reveals potential of APG-stabilized vehicles as prospective delivery systems using several model drugs and cosmetic actives Includes an up-to-date review of research conducted in the field of APGs, facilitating future preformulation and formulation studies for researchers Offers a concise and practical compendium of characterization techniques

Biomedical Imaging: Applications and Advances discusses the technologies and latest developments in the increasingly important field of imaging techniques for the diagnosis of disease, monitoring of medical implants, and strategies for personalized medicine.

Chapters in part one explore the full range of imaging technologies from atomic force microscopy (AFM) to positron emission tomography (PET), as well as the next-generation techniques that could provide the basis for personalized medicine. Part two highlights application-specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging, and the use of brain imaging to assess post-therapy responses. Further chapters review intravascular, cardiovascular, and whole-body magnetic resonance imaging (MRI).

Biomedical Imaging is a technical resource for those concerned with imaging and diagnosis, including materials scientists and engineers as well as clinicians and academics.

• Explores the full range of imaging technologies from atomic force microscopy (AFM) to positron emission tomography (PET), as well as next-eneration techniques for personalized medicine
• Highlights application-specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging, and the use of brain imaging to assess post therapy responses
• Reviews intravascular, cardiovascular, and whole-body magnetic resonance imaging (MRI)

Biomedical Imaging: Applications and Advances discusses the technologies and latest developments in the increasingly important field of imaging techniques for the diagnosis of disease, monitoring of medical implants, and strategies for personalized medicine. Chapters in part one explore the full range of imaging technologies from atomic force microscopy (AFM) to positron emission tomography (PET), as well as the next-generation techniques that could provide the basis for personalized medicine. Part two highlights application-specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging, and the use of brain imaging to assess post-therapy responses. Further chapters review intravascular, cardiovascular, and whole-body magnetic resonance imaging (MRI). Biomedical Imaging is a technical resource for those concerned with imaging and diagnosis, including materials scientists and engineers as well as clinicians and academics. Explores the full range of imaging technologies from atomic force microscopy (AFM) to positron emission tomography (PET), as well as next-eneration techniques for personalized medicine Highlights application-specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging, and the use of brain imaging to assess post therapy responses Reviews intravascular, cardiovascular, and whole-body magnetic resonance imaging (MRI) Content: Part 1 Fundamentals of porous silicon for biomedical applications: Porous silicon for biomedical applications: From conception to clinical use; Thermal stabilization of porous silicon for biomedical applications; Thermal properties of nanoporous silicon materials; Photochemical and non-thermal chemical modification of porous silicon for biomedical applications; Modifying porous silicon with self-assembled monolayers for biomedical applications; Protein-modified porous silicon films for biomedical applications; Biocompatibility of porous silicon for biomedical applications. Part 2 Porous silicon for bio-imaging and bio-sensing applications: Optical properties of porous silicon materials for biomedical applications; In vivo imaging assessment of porous silicon; Radiolabeled porous silicon for bio-imaging applications; Desorption/ionization on porous silicon (DIOS) for metabolite imaging; Porous silicon for bacteria detection; Nanoporous silicon biosensors for DNA sensing. Part 3 Porous silicon for drug delivery, cancer therapy and tissue engineering applications: Drug loading and characterization of porous silicon materials; Nanoporous silicon to enhance drug solubility; Multistage porous silicon for cancer therapy; Porous silicon for tumour targeting and imaging; Porous silicon - polymer composites for cell culture and tissue engineering applications; Porous silicon and related composites as functional tissue engineering scaffolds; Porous silicon scaffolds for stem cells growth and osteodifferentiation. " Porous silicon is rapidly attracting increasing interest in the biomaterials community. This nanostructured and biodegradable material has a range of properties, making it ideal for drug delivery, cancer therapy, and tissue engineering. Porous silicon for biomedical applications provides a comprehensive review of this emerging biomaterial. Chapters in part one focus on the fundamentals and properties of porous silicon for biomedical applications including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein-modified porous silicon films, and biocompatibility of porous silicon. Part two discusses applications in bioimaging and sensing and explores the optical properties of porous silicon materials, in vivo imaging assessment and radiolabelling of porous silicon, and nanoporous silicon biosensors for DNA sensing and for bacteria detection. Finally, part three highlights drug loading and characterization of porous silicon materials, tumour targeting and imaging, and porous silicon scaffolds for functional tissue engineering and stem cells growth and osteodifferentiation. With its acclaimed editor and international team of expert contributors, Porous silicon for biomedical applications is a technical resource and indispensable guide for all those involved in the research, development and application of porous silicon and also other biomaterials, whilst providing a comprehensive introduction for students and academics interested in the field. " -- The last page of cover Annotation The development of imaging techniques is of great importance for the monitoring of medical implants, diagnosis of disease, and strategies for personalized medicine. Significant advances are being made in this technology; editor Peter Morris has brought together a roster of contributing editors to discuss the latest advances and developments in this important field. Chapters in part one explore the full scale of imaging technologies from Atomic Force Microscopy (AFM) to Positron Emission Tomography (PET), as well as the Next Generation techniques that could provide the basis for personalized medicine. Part two highlights application specific biomedical imaging methods, including ophthalmic imaging of ocular circulation, imaging methods for detection of joint degeneration, neural brain activation imaging and the use of brain imaging to assess post therapy responses. Further chapters review intravascular, cardiovascular and whole body magnetic resonance imaging (MRI) The development of imaging techniques is of great importance for the diagnosis of disease, monitoring of medical implants and for strategies for personalised medicine. Significant advances are being made in this technology and Biomedical imaging discusses the technologies and latest developments in this increasingly important field. Chapters in part one explore the full scale of imaging technologies from Atomic Force Microscopy (AFM) to Positron Emission Tomography (PET), as well as the Next Generation techniques that could provide the basis for personalised medicine. Part two highlight This book discusses the core technologies needed for these sophisticated devices and their current and potential medical applications.