Phytochemistry of medicinal plants : [proceedings of the thirty-fourth annual meeting of the Phytochemical society of North America on phytochemistry of medicinal plants, held August 15-19, 1994, in Mexico City, Mexico

Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low­ cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel. Front Matter....Pages i-viii Immunostimulants and Adaptogens from Plants....Pages 1-18 Natural Product Cancer Chemopreventive Agents....Pages 19-45 Antiviral and Antitumor Plant Metabolites....Pages 47-64 Biological Diversity of Medicinal Plants in México....Pages 65-82 Bioactive Natural Products from Traditionally used Mexican Plants....Pages 83-112 Bioassay-Guided Isolation and Structure Elucidation of Pharmacologically Active Plant Substances....Pages 113-135 Biologically Active Compounds from Chilean Medicinal Plants....Pages 137-159 Phytochemicals Ingested in Traditional Diets and Medicines as Modulators of Energy Metabolism....Pages 161-188 Applications of Liquid Chromatography-Mass Spectrometry to the Investigation of Medicinal Plants....Pages 189-215 Root Culture as a Source of Secondary Metabolites of Economic Importance....Pages 217-248 Annonaceous Acetogenins....Pages 249-310 Neo-Clerodane Diterpenoids from American Salvia Species....Pages 311-332 Sesquiterpene Lactones Revisited....Pages 333-356 Back Matter....Pages 357-364