Phosphate And Mineral Homeostasis (advances In Experimental Medicine And Biology)

Front Matter....Pages i-xiv Front Matter....Pages 1-1 High Energy Phosphates, Phospholipids, and Calcium in Ischemic Renal Tubular Cell Injury....Pages 3-7 Calcium, Cell Function and Cell Death....Pages 9-15 Primary Hyperparathyroidism (PHP) Revisited....Pages 17-45 Front Matter....Pages 47-47 Mechanisms of Ion Transport Regulation by Parathyroid Hormone: cAMP/Ca 2+ /Calmodulin and Phospholipid Dependent Phosphorylation....Pages 49-57 Mechanisms of NAD Action in Regulation of Renal Brush Border Membrane Transport of Phosphate....Pages 59-66 Interactions between Inorganic Phosphate and Energy Metabolism in Renal Cortical Tubules....Pages 67-72 Regulation of Na-Phosphate Cotransport in Cultured Renal Epithelial Cells: Protein-Synthesis-Dependent and Protein-Synthesis-Independent Pathways....Pages 73-82 Phosphorin, A Phosphate-Binding Hydrophobic Protein Isolated from Renal Brush Border Membranes....Pages 83-92 Intrarenal Phosphate Reabsorption: Role of Nephron Heterogeneity....Pages 93-99 Resistance to the Phosphaturic Effect of Parathyroid Hormone during Phosphate Conservation is due to Enhanced Phosphate Reabsorption by the Pars Recta....Pages 101-108 Brush Border Membrane Phosphate Transport Effects of Volume Expansion....Pages 109-113 The Direct Effect of 1,25-Dihydroxycholecalciferol on Membrane Phospholipid Composition and Phosphate Transport....Pages 115-124 Possible Role of Calcium in Parathyroid Hormone Action on Phosphate Transport in Rabbit Renal Proximal Tubules....Pages 125-132 Calcium Stimulates Sodium-Dependent Phosphate Absorption in Rabbit Proximal Convoluted Tubules Perfused in Vitro....Pages 133-135 Characteristics of Phosphate Transport Across the Basolateral Membrane of the Proximal Tubule: An in Vivo Study....Pages 137-143 Renal Proximal Tubular Brush-Border Membrane Transport of Phosphate with Acute Acidosis....Pages 145-153 Effects of Glucagon on Renal and Extrarenal Handling of Pi in Rodents: Evidence for Pi Mobilizing Activity....Pages 155-162 Front Matter....Pages 164-164 Calcium Transport by the Proximal Tubule....Pages 165-170 Mechanisms of Calcium Transport in the Thick Ascending Limb of the Loop of Henle....Pages 171-175 Calcium Transport in the Distal Convoluted Tubule....Pages 177-182 Front Matter....Pages 164-164 Renal Membrane Transport of Calcium....Pages 183-186 Renal Tubular Disorders Associated with Hypocalciuria....Pages 187-191 Renal Magnesium Wasting Disorders....Pages 193-197 Role of PTH, Vitamin D and Bone Metabolism in Low Protein-Induced Hypercalciuria....Pages 199-204 Front Matter....Pages 205-205 Mechanism and Regulation of Intestinal Phosphate Transport....Pages 207-212 Intestinal Absorption of Phosphate in Man: Effect of Drugs....Pages 213-222 Mechanism of Phosphate Transport Adaptation in Rat Intestinal and Renal Brush Border Membranes....Pages 223-226 Analysis of Calcium Transport in Rat Intestine....Pages 227-234 Calcium Absorption in the Rat Colon Measured in Vivo....Pages 235-238 Impaired Intestinal Calcium Transport in the Spontaneously Hypertensive Rat....Pages 239-243 Front Matter....Pages 245-245 Cellular Mechanisms of Bone Remodeling Evaluated at the Intermediary Level of Organization of Bone....Pages 247-254 The Local Regulation of Bone Remodeling....Pages 255-259 Immune Cells and Bone Resorption....Pages 261-273 Bisphosphonates can Reduce Osteoclastic Bone Resorption by Two Different Mechanisms....Pages 275-281 Comparison of Aluminum Related with Vitamin D Related Osteomalacia by Tetracycline Based Bone Histomorphometry....Pages 283-287 Parathyroid Hormone and 1.25 Vitamin D 3 Exert Opposite Effects on Bone....Pages 289-290 Serum Bone Gla-Protein Compared to Bone Histomorphometry in Hemodialyzed Patients....Pages 291-296 Effects of 1,25(OH) 2 D 3 Administration on Serum Bone GLA Protein in Predialysis Chronic Renal Failure....Pages 297-303 Skeletal Mass in Long Term Hemodialysis Patients....Pages 305-311 Front Matter....Pages 313-313 Parathyroid Hormone Antagonists Effective in Vivo ....Pages 315-327 Front Matter....Pages 313-313 Solubilization of a Guanine Nucleotide-Sensitive Parathyroid Hormone-Receptor Complex from Canine Renal Cortex....Pages 329-343 Parathyroid Hormone Secretory Responses to Peroral Phosphate and Stimulability of Serum Levels of Carboxyl-Terminal Flanking Peptide (PND-21) of the Human Calcitonin Gene by Calcium in Normal Subjects and Osteoporotic Patients....Pages 345-349 Renal Adenylate Cyclase Stimulating Action of Normal and Oxidized Parathyroid Hormone (1–34)....Pages 351-356 Hypercalcemia of Malignancy....Pages 357-366 Mechanism of the Hypocalcemic Agent WR-2721 and Its Acute and Chronic Application in Eu- and Hyperparathyroidism....Pages 367-370 Determinants of Circulating Levels of 1.25(OH) 2 D 3 (Calcitriol) in Primary Ry Hyperparathyroidism (PHPT)....Pages 371-378 Mechanism of Nephrocalcinosis in Primary Hyperparathyroidism....Pages 379-382 Changes in Serum Calcium and Phosphorus Induced by Chronic Renal Failure in the Absence of Parathyroid Hormone....Pages 383-386 Front Matter....Pages 387-387 Theoretical Mechanisms of Dietary Calcium’s Antihypertensive Action....Pages 389-396 Calcium as a Mediator of Salt Sensitive Hypertension....Pages 397-404 The Effect of Calcium on Renin, Aldosterone and Prostaglandin Release....Pages 405-416 Disturbed Phosphate Metabolism in Spontaneously Hypertensive Rats....Pages 417-422 Participation of Various Brain Nuclei in the Altered Time Course of Genetic Hypertension in SHR Dependent on Changes in Calcium Metabolism....Pages 423-431 Dissociation between the Hypotensive Effect of Thiazides and Plasma Divalent Cations....Pages 433-441 Front Matter....Pages 443-443 Urine Citrate and Calcium in Calcium Nephrolithiasis....Pages 445-449 Influence of Oxalate on Calcium Oxalate Crystals Formation in Urine....Pages 451-458 Therapeutic Modalities for the Prevention of Nephrolithiasis....Pages 459-465 Front Matter....Pages 467-467 Factors Controlling the Intracellular Concentration of Orthophosphate (Pi) in Mammalian Cells....Pages 469-478 Phosphate Transfer and 31 P Nuclear Magnetic Resonance (NMR) Spectroscopy Pre and Post Hemofiltration (HF)....Pages 479-484 Regulation of Renal Na-K-ATPase: Effects of Aldosterone in Phosphate Depletion....Pages 485-492 Front Matter....Pages 467-467 Effects of the Impairment of Renal Function and of the pH of Gastric Secretion on the Efficacy of Al(OH) 3 to Reduce Serum Inorganic Phosphorus....Pages 493-499 Effects of Different Insulin Administration Modalities on Vitamin D Metabolism of Insulin-Dependent Diabetic Patients....Pages 501-508 Influence of Inorganic Phosphate on Glucose-Induced Insulin Release in Vitro....Pages 509-515 Mechanism of Inhibition of Glycolysis by Vanadate....Pages 517-528 Regulation of Na + /H + Antiport in the Intact Renal Proximal Tubular Cell....Pages 529-532 Interaction of Vitamin D-Metabolites with Adenylate Cyclase/Cyclic AMP System: A Biological Model of Controlled Regulation....Pages 533-536 Dibutryladenosine 3’, 5’-Cyclic Monophosphate (dBcAMP) does not Mimic the Action of Parathyroid Hormone (PTH) on Canine Proximal Tubular Basolateral Membrane Na + :Ca 2+ ....Pages 537-541 Phosphate Transport Through Placenta Brush Border Membrane....Pages 543-548 Back Matter....Pages 549-553