Pharmacokinetics of Oral Contraceptive Steroids and Drug Interaction: Salzburg, Austria, September 14-16, 1989

American Journal of Obstetrics and Gynecology, Volume 163, Issue 6, Part 2, Pages 2113–2218. From: https://archive.org/details/sim\_american-journal-of-obstetrics-and-gynecology\_1990-12\_163\_supplement/ https://www.sciencedirect.com/journal/american-journal-of-obstetrics-and-gynecology/vol/163/issue/6/part/P2 Front Page Title Page Contents Introduction (Kuhl) I. Pharmacokinetics of Oral Contraceptive Steroids (Fotherby) Pharmacokinetics of ethinyl estradiol and mestranol (Goldzieher) Pharmacokinetics of the contraceptive steroids levonorgestrel and gestodene after single and multiple oral administration to women (Kuhnz) Pharmacologic and pharmacokinetic characteristics of norgestimate and its metabolites (McGuire et al.) Serum pharmacokinetics of orally administered desogestrel and binding of contraceptive progestogens to sex hormone -binding globulin (Bergink et al.) II. Gastrointestinal Metabolism of Oral Contraceptive Steroids (Hammerstein) Gastrointestinal metabolism of contraceptive steroids (Back, Madden, & Orme) Factors affecting the enterohepatic circulation of oral contraceptive steroids (Orme & Back) III. Hepatic Metabolism of Oral Contraceptive Steroids (Orme) Interactions with oral contraceptives (Fotherby) Inhibition of oral contraceptive steroid-metabolizing enzymes by steroids and drugs (Guengerich) Formation, metabolism, and physiologic importance of catecholestrogens (Ball & Knuppen) IV. Hormonal Effectiveness of Oral Contraceptive Steroids (Breckwoldt) Binding of oral contraceptive progestogens to serum proteins and cytoplasmic receptor (Juchem & Pollow) Pharmacokinetics and pharmacodynamics of oral contraceptive steroids: Factors influencing steroid metabolism (Jung-Hoffmann & Kuhl) Prodrugs: Advantage or disadvantage? (Hammerstein) V. Clinical Implications (Taubert) Gastrointestinal disease and oral contraception (Hanker) Influence of oral contraceptives on drug therapy (Teichmann) Oral contraception in disease states (Breckwoldt, Wieacker, & Geisthövel) Conclusion (Kuhl)