PET/CT in Radiotherapy Planning (Clinicians’ Guides to Radionuclide Hybrid Imaging)

This pocket book offers a succinct but comprehensive overview of the role of PET/CT in radiotherapy planning. Individual chapters are devoted to specific application of the technique to particular tumor types, including non-small cell lung, gastrointestinal, head and neck squamous cell, prostate, gynecological, and pediatric tumors. Helpful information is also presented on the practical implementation of PET/CT in routine oncological practice. Technical and logistical issues are discussed, and guidance provided on potential problems and pitfalls and available solutions. The book will be invaluable in assisting readers to exploit PET/CT’s ability to significantly improve delineation of tumor tissue through the addition of metabolic information to structural imaging data, thereby avoiding unnecessary radiation injury and associated complications while enhancing therapeutic effects and minimizing the risk of marginal recurrences. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging , compiled under the auspices of the British Nuclear Medicine Society. Foreword Preface Acknowledgements Contents Contributors Part I: Radiotherapy Planning in Oncology: Science and Practice 1: Introduction 1.1 Introduction 1.2 EBRT Planning Process 1.3 Role of PET/CT in RT Planning 1.4 PET-MRI References Part II: PET/CT in Radiotherapy Planning - Technical and Practical Aspects 2: Instrumentation References 3: Patient Preparation 3.1 Patient Positioning 3.2 Other Considerations References 4: Data Acquisition, Reconstruction and Transfer 4.1 PET Acquisition and Reconstruction: Standard Options in PET Scanning 4.2 Deviation for RT Planning PET 4.3 CT Acquisition: Standard Options in Diagnostic Scanning 4.4 Deviation for RT Planning CT 4.5 Respiratory Gating 4.6 DICOM, DICOM-RT and Other Options References 5: Sources of Artefacts: Consequences and Solutions References 6: Advantages and Limitations 6.1 Introduction 6.2 Advantages 6.2.1 Accuracy in Disease Delineation 6.2.2 Future Potential for Individualizing Radiotherapy Treatment 6.3 Considerations and Limitations References 7: 4D PET/CT Respiratory Gated Acquisition Techniques 7.1 Introduction 7.2 Breath-Hold Techniques 7.3 4D PET/CT References Part III: PET/CT in Radiotherapy Planning - Current Evidence and Applications 8: Lung Cancer References 9: Head and Neck Cancers 9.1 Introduction 9.2 Staging 9.3 Target Volume Definition 9.4 Dose Painting and Adaptive Radiotherapy 9.5 Treatment Response Evaluation References 10: GI Malignancy 10.1 Introduction 10.2 Rectal Cancer 10.3 Oesophageal and Pancreatic Cancer 10.4 Summary References 11: Prostate Cancer 11.1 Patient Selection for Treatment 11.2 Target Volume Delineation References 12: Gynaecological Cancers 12.1 Cervix Cancer 12.2 Endometrial Cancer 12.3 Novel PET Tracers References 13: Paediatric Tumours 13.1 Introduction 13.2 Indications 13.3 Patient Preparation 13.4 Scan Protocol 13.5 Tumour Delineation References Index