Personalized Cancer Chemotherapy : An Effective Way of Enhancing Outcomes in Clinics

Personalized Cancer Chemotherapy separately describes and addresses "individualized cancer chemotherapy" (ICC) strategies new and old, to provide readers with new insights into their characteristics and techniques, as well as key debates and future trends in this area. The book devotes chapters to drug sensitivity testing, cancer biomarkers and bioinformatics detection, pharmacogenetics, individualized antimetastatic therapy, drug combinations, assistant chemotherapy, and cost-effectiveness considerations. A major obstacle to controlling cancer growth and metastases in patients is the inappropriate use of anticancer and antimetastatic drugs. Researchers and clinicians are now beginning to focus on ICC also called "personalized cancer chemotherapy" (PCC), to improve therapeutic quality and outcomes by selecting and prescribing the most appropriate and effective drugs. Using genetic, molecular, and bioinformatics data and modern experimental techniques, known tumor genes can be detected more easily than ever before; the average speed of genetic sequencing has increased 15,000 to 50,000 times since the Human Geonme Project was completed. This book will help readers understand the pros and cons of each individualized cancer chemotherapy strategy from different angles so as to make good judgments and predictions of drug responses and clinical outcomes. Explores the central components of cancer treatment Investigates new developments in cancer treatment Discusses the many strategies of individualized cancer chemotherapy

Individualized cancer chemotherapy (ICC) has been designed to meet the requirement of selecting anticancer drugs in clinics and attracting increasing attentions in medical circle and will show more beneficial outcome in the future if we stick on these researches. Personalized Cancer Chemotherapy addresses and reviews this issue by discussing many existing specific strategies of ICC, including drug sensitivity testing, cancer biomarker detections, cancer biomarker-oriented therapy, anticancer drug pharmacogenetics, cancer metastasis therapy, anticancer drug combinations, assistant therapy, mathematics, and computational analysis of cancer malignancy and drug responses, cost effective and finally studies of relationship between different ICC strategies. The relationship between drug response and these techniques or methods is in-depth analyzed, discussed and highlight. Many longstanding key debates and future trends are also intensively discussed, highlighted and debuted with new twists.

• Explores the central components of cancer treatment
• Investigates new developments in cancer treatment
• Discusses the many strategies of individualized cancer chemotherapy

__Personalized Cancer Chemotherapy__ separately describes and addresses "individualized cancer chemotherapy" (ICC) strategies new and old, to provide readers with new insights into their characteristics and techniques, as well as key debates and future trends in this area. The book devotes chapters to drug sensitivity testing, cancer biomarkers and bioinformatics detection, pharmacogenetics, individualized antimetastatic therapy, drug combinations, assistant chemotherapy, and cost-effectiveness considerations. This book will help readers understand the pros and cons of each individualized cancer chemotherapy strategy from different angles so as to make good judgments and predictions of drug responses and clinical outcomes. Content: Front Matter, Page iii Copyright, Page iv List of figures and tables, Page ix About the author, Page xi Preface, Pages xiii-xvii List of abbreviations, Page xix 1 - Introduction, Pages 1-4 2 - Drug sensitivity testing, Pages 5-11 3 - Individualized cancer chemotherapy via cancer biomarkers or bioinformatics detection, Pages 13-19 4 - Pharmacogenetics, Pages 21-28 5 - Individualized antimetastatic therapy [1–2], Pages 29-36 6 - Drug combinations, Pages 37-41 7 - Assistant chemotherapy, Pages 43-48 8 - Cost-effectiveness considerations, Pages 49-53 9 - Discussion, Pages 55-60 10 - Conclusion, Pages 61-64