Peritoneal Surgery

**Peritoneal Surgery** addresses the response of the peritoneum to injury and the prevention of post-surgical adhesions resulting from general and gynecologic surgery. Adhesions, or scar tissue binding two normally separate surfaces, form when the peritoneum, the membrane covering the abdominal wall and protecting the inner organs, is damaged during surgery, inflammation, or injury. Negative complications from adhesions include pelvic pain, infertility, intestinal obstruction, multiple surgical complications resulting from surgery to remove or pull them apart, and therefore a greater surgical workload and economic burden to the healthcare system. In this book, experts in the field address peritoneal repair, the role of surgical technique to prevent adhesions, adhesion formation, complications of adhesions, and developing technology in the prevention of adhesions. Front Matter....Pages i-xxiii Front Matter....Pages 1-1 Peritoneum, Peritoneal Healing, and Adhesion Formation....Pages 3-37 Peritoneal Fluid....Pages 39-49 Peritoneal Tissue Repair Cells....Pages 51-64 The Biology of Peritoneal Tissue Repair....Pages 65-74 Cytokine Responses to Peritoneal Inflammation: The Role of the Mesothelium....Pages 75-84 The Role of Integrins in Peritoneal Healing....Pages 85-99 Proteases and Protease Inhibitors in Tissue Repair....Pages 101-113 Front Matter....Pages 115-115 The Plasmin System, a Marker of the Propensity to Develop Adhesions....Pages 117-131 Peritoneal Fibrinolysis and Adhesion Formation....Pages 133-142 Front Matter....Pages 143-143 Laparoscopic Myomectomy....Pages 145-152 Foreign Materials....Pages 153-174 The Peritoneum and Laparoscopy....Pages 175-181 Adhesions: Laparoscopy Versus Laparotomy....Pages 183-192 Reducing Adhesion Formation in Gynecologic Procedures Using Laparoscopic Surgery....Pages 193-199 Role of Sutures and Suturing in the Formation of Postoperative Adhesions....Pages 201-208 Pollutants Resulting from Intraabdominal Tissue Combustion....Pages 209-214 Front Matter....Pages 215-215 Incidence of Postsurgical Adhesions....Pages 217-220 Classification of Adhesions....Pages 221-228 Conventional Radiography and Cross-Sectional Imaging Modalities in the Diagnosis of Adhesions....Pages 229-234 Ectopic Pregnancy and Adhesion Formation....Pages 235-239 Front Matter....Pages 215-215 Ovarian Surgery and Laparoscopy....Pages 241-251 Peritoneal Endometriosis....Pages 253-263 Prognostic Factors of Distal Tubal Occlusion....Pages 265-274 Endometriosis, Endometrioma, and the Problem of Adhesions....Pages 275-288 Myomectomy and Adhesion Formation....Pages 289-294 Front Matter....Pages 295-295 The Magnitude of Adhesion-Related Problems....Pages 297-306 Prevalence of Adhesions and the Associated Costs in General Surgery....Pages 307-320 Outcome Measures and Adhesion Formation: Pain and Postsurgical Adhesion....Pages 321-327 Infertility and Adhesions....Pages 329-333 Contributions of Adhesions to the Cost of Healthcare....Pages 335-342 Clinical Significance of Adhesions in Patients with Chronic Pelvic Pain....Pages 343-348 Front Matter....Pages 349-349 Development and Clinical Evaluation of Intergel Adhesion Prevention Solution for the Reduction of Adhesions Following Peritoneal Cavity Surgery....Pages 351-366 Laparoscopic Treatment of Peritoneal Adhesions....Pages 367-378 Use of Adhesion Prevention Barriers in Pelvic Reconstructive and Gynecologic Surgery....Pages 379-399 Adhesion Prevention: Past the Future....Pages 401-417 Front Matter....Pages 419-419 Transperitoneal Pharmacokinetics....Pages 421-439 Developing Pharmacologic Agents for Adhesion Prevention....Pages 441-457 Animal Adhesion Models: Design, Variables, and Relevance....Pages 459-476 Adhesion Prevention: The Role of Fibrin Glue....Pages 477-481 Bioadhesive Polymers That Reduce Adhesion Formation....Pages 483-497 Front Matter....Pages 419-419 Polymer Solutions and Films as Tissue-Protective and Barrier Adjuvants....Pages 499-520 Back Matter....Pages 521-532