Pediatric Oncology 1: With A Special Section On Rare Primitive Neuroectodermal Tumors (cancer Treatment And Research) (volume 2)

Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco­ logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre­ quently publish good indepth reviews of cancer topics, and published sympo­ sium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid­ ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the Specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more. Front Matter....Pages i-xiii Front Matter....Pages 1-1 Abnormal Immunoregulation in Pediatric Cancer and Immunodeficiency....Pages 3-45 The Potential Use of HLA to Predict Risk of Malignant Diseases and Outcome of Therapy....Pages 47-77 Interferon and Cancer....Pages 79-98 Tumor Heterogeneity....Pages 99-116 Biological Markers of the Tumors of the Central Nervous System....Pages 117-163 Non-Chemotherapeutic Approaches to Uncontrolled CNS Tumors....Pages 165-197 Advantages and Disadvantages of Adjuvant Chemotherapy in the Treatment of Primary CNS Tumors....Pages 199-211 Front Matter....Pages 213-213 Primitive Neuroectodermal Tumors of Brain in Childhood: Literature Review and the M. D. Anderson Experience....Pages 215-224 Primary Cerebral Neuroblastomas....Pages 225-228 Cerebral Primitive Neuroectodermal Tumor (Primary Cerebral Neuroblastoma): CHLA Experience....Pages 229-234 Supratentorial Primitive Neuroectodermal Tumor: Clinical Response of a Single Case to Vincristine, Cyclophosphamide, and BCNU....Pages 235-237 Review of Experience with Primitive Neuroectodermal Tumors of Childhood....Pages 239-242 Primitive Neuroectodermal Tumour....Pages 243-246 Primitive Neuroectodermal Tumors (Embryonal Gliomas) of Childhood. A Clinicopathologic Study of 12 Cases....Pages 247-264 Primitive Neuroectodermal Tumors of Infancy and Childhood....Pages 265-267 Poorly Differentiated Small Cell Tumours of the Central Nervous System that Are Not Medulloblastomas....Pages 269-276 Primitive Neuroectodermal Tumors of the Central Nervous System in Childhood. Retrospective and Overview....Pages 277-288 Overview on the Management of Primitive Neuroectodermal Tumors....Pages 289-294 Back Matter....Pages 295-298 Where do you begin to look for arecent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco­ logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre­ quently publish good in-depth reviews of cancer topics, and published sym­ posium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is aseries of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. Wehave approached the problem in the following fashion. First, by divid­ ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, supportive care, etc. Second, by asking eminent autho­ rities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more. Pulmonary cacinogenesis / Theodore L. McLemore, R. Russell Martin Adjuvant therapy with surgery / William P. McGuire The immunotherapy of lung cancer / E. Carmack Holmes The use of pre-operative radiation therapy in the treatment of lung carcinoma / David M. Sherman, Ralph R. Weichselbaum Lung cancer-post resection irradiation / Nathan Green The role of radiation therapy in the treatment of regional non-small (oat)-cell carcinoma of the lung / Joel Eliot White, Murray Boles Small cell anaplastic carcinoma of the lung / Heine H. Hansen, Per Dombernowsky Small cell bronchogenic carcinoma / Paul A. Bunn, Jr., Daniel C. Ihde Radiation therapy-new approaches / Omar M. Salazar, Gunar Zagars Pathology of small cell carcinoma of the lung and its subtypes / Mary J. Matthews, Adi F. Gazdar. However, despite optimal treatment with surgery and radiotherapy, patients with nodal spread or extensive local disease have a low cure rate. New, creative methods of radiation therapy delivery, such as the use of multiple fractions per day, as discussed by Parsons and Million, are also contributing to long-term local control.