Pediatric Germ Cell Tumors: Biology Treatment Survivorship (Pediatric Oncology Book 1)

Germ cell tumors are relatively rare compared with other malignancies, and compilations of knowledge that encompass the entire spectrum of the disease are lacking. This textbook, written by the foremost authorities in the field, rectifies the situation by discussing in depth a broad range of topics, including biology, epidemiology, pathology, treatment, and late effects. Bearing in mind that germ cell tumors are most prevalent in the adolescent and young adult age group, causes of disease and treatment approaches in pediatric and adult patients are compared and contrasted. By spanning the entire life course, from prenatal origins of disease through to treatment in adults and late effects of treatment, the editors have produced a book that will be of interest to both pediatric and adult oncologists. Front Matter....Pages i-xii Biology of Germ Cell Tumors....Pages 1-15 Epidemiology of Germ Cell Tumors....Pages 17-36 Pathology of Germ Cell Tumors....Pages 37-58 Clinical Treatment of Extracranial Pediatric Germ Cell Tumors....Pages 59-78 Management of Disseminated Germ Cell Tumor in Adults....Pages 79-90 Clinical Treatment of Adult Women with Ovarian Germ Cell Tumors....Pages 91-99 Ovarian and Testicular Sex Cord-Stromal Tumors....Pages 101-113 Late Effects in Testicular Cancer Survivors....Pages 115-131 Back Matter....Pages 133-135