Parkinson's disease : a guide to medical treatment

In Parkinson's disease, the past half-century of research has brought many fascinating advances in treatment. Proper identification and treatment of both motor and non-motor symptoms lead to a better overall quality of life, reducing stress incurred by both patient and caregiver. This book provides a comprehensive description of current treatment options for patients with Parkinson's disease. The text concludes with a section of FAQs, born from the experience of the authors with patients and their families. Title Page; Colophon ; Sommario; 1 Epidemiology, Diagnosis, and Pathophysiology of Parkinson's Disease; 1.1 A Brief History of Parkinson's Disease; 1.2 Clinical Features of Parkinson's disease; 1.3 Epidemiology of Parkinson's Disease; 1.4 The Neurochemistry of Parkinson's Disease; 1.5 Pathophysiology of Parkinson's Disease; 1.6 Diagnosing Parkinson's Disease; 1.7 The Stages of PD; References; 2 Pharmacology of Treatments for Parkinson's Disease Motor Symptoms; 2.1 Levodopa and Levodopa/Carbidopa; 2.2 Dopamine Agonists; 2.3 Catechol-O-Methyltransferase (COMT) Inhibitors. 2.4 Anticholinergic medications2.5 Amantadine (Symmetrel®, Symadine®); 2.6 Monoamine Oxidase B (MAO-B) Inhibitors; References; 3 Medical Management of Motor Symptoms of Parkinson's Disease; 3.1 Management of Early Parkinson's Disease; 3.2 Treatment of Advancing Parkinson's Disease: Levodopa Rescue; 3.3 Management of Advanced Parkinson's Disease: Complications of Therapy; 3.4 Considerations for the Management of Hospitalized Patients With Parkinson's Disease; 3.5 Conclusion; References; 4 Treatment of Neuropsychiatric Symptoms in PD; 4.1 Treatment of Depression and Anxiety. 4.2 Treatment of Dopaminergic-induced Psychosis4.3 Treatment of Impulse Control Behaviors; 4.4 Treatment of Cognitive Impairment and Dementia in PD; References; 5 Clinical Treatment of Dysautonomia in PD; 5.1 Orthostatic Hypotension; 5.2 Sexual Dysfunction; 5.3 Constipation; 5.4 Siallorhea; 5.5 Abnormal Sweating (Dyshidrosis); 5.6 Urinary Incontinence; References; 6 Clinical Treatment of Sleep Disorders in PD; 6.1 Insomnia; 6.2 Treatment of Excessive Daytime Somnolence and Sleep Attacks; 6.3 Treatment of Restless Leg Syndrome and Periodic Limb Movements of Sleep. 6.4 Treatment of REM Sleep Behavior DisorderReferences; 7 Clinical Treatment of Non-motor Symptoms, Sensory Abnormalities and Fatigue; 7.1 Treatment of Pain in PD; 7.2 Treatment of Fatigue in PD; References; 8 Patient Q & A: 25 Questions About PD and the Clinical Management of its Motor and Non-motor Symptoms; 8.1 How fast does PD progress? What can I expect in the coming years in terms of mobility?; 8.2 I recently was diagnosed with PD. Can my adult children get PD?; 8.3 Are generic medications different from brand names? Can I use them?; 8.4 How often should I be seeing my physician for PD? 8.5 Should I have a primary care physician?8.6 I am a female who was recently diagnosed with PD, and I have a long history of oral contraceptive use. A friend told me she read that birth control use may put you at higher risk for developing PD. Is this true?; 8.7 What are some future treatments for PD? Does stem cell therapy play a role?; 8.8 What is gene therapy?; 8.9 What surgical treatment options are available for patients with PD? Are all PD patients candidates for surgery? Annotation In Parkinsons disease, the past half-century of research has brought many fascinating advances in treatment. Proper identification and treatment of both motor and nonmotor symptoms led to a better overall quality of life, reducing stress endured by both patient and caregiver. This book provides a comprehensive description of current treatment options for patients with Parkinsons disease