Pain Killer : An Empire of Deceit and the Origin of America's Opioid Epidemic

"Groundbreaking ... 'he shocking account of the origins of today's opioid epidemic, the creators of this plague, and the way to help stop it."'Sam Quinones, author of Dreamland: The True Tale of America's Opiate Epidemic "Prescient ... ' landmark work of investigative journalism."'David A. Kessler, former commissioner of the Food and Drug Administration and author of The End of Overeating Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma's aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. In Pain Killer, Pulitzer Prize'winning New York Times reporter Barry Meier exposes the roots of the most pressing health epidemic of the twenty-first century. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. Purdue turned OxyContin into a billion-dollar blockbuster by launching an unprecedented marketing campaign claiming that the drug's long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin's use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. The drugmaker's owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In this updated edition of Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department's failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business expose, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy Pain Killer OxyContin, a potent painkiller containing opium-derived oxycodone as its key active ingredient, was first sold in 1996 as a treatment for cancer patients and other chronic pain sufferers. From the start, the drug's manufacturer aggressively marketed its patented time-release formula as a breakthrough in the effort to reduce prescription drug abuse. It wasn't long, however, before thrill-seeking teenagers shattered that illusion of safety; by simply crushing an "Oxy," they were able to tap into a high so seductive it would come to dominate their lives. Some patients, seeking relief from pain, also found themselves drawn to the drug's dark side. Pain Killer takes readers on a journey of discovery that begins with the true story of Lindsay, a high-school cheerleader in Virginia who gets hooked on Oxys, and expands outward to explore the critical issues of legitimate pain management, prescription drug abuse, and how the misuse of science by the drug industry threatens the public good. With the fast-rising abuse of prescription drugs by young people ringing alarm bells within government, the how and why behind the OxyContin disaster is a gripping read not only for parents, but also for medical professionals, community leaders, business executives, and all those concerned with this crisis. The dangers described in Pain Killer also reverberate far beyond the threat from a single drug at a particular moment in time. The focus of our government's war on drugs has clearly misled many of us into thinking that only illegal drugs smuggled from beyond our borders can be abused. As Meier tells the dramatic story, some of the most deadly substances are produced and sold legally right here at home. THE EXTRAORDINARY AND TRUE STORY OF OXYCONTIN EQUAL PARTS crime thriller, medical detective story, and business exposé, Pain Killer takes a hard-hitting look at how a powerful drug touted as the salvation for millions triggered a national tragedy. At its inception, the legal narcotic OxyContin was seen as a pharmaceutical dream, a "wonder" drug that would herald a sea change in medical care while reaping vast profits for its maker. It did do that; but it also unleashed a public health crisis that cut a swath of despair and crime through unsuspecting small towns, suburbs, and cities across the country. As reports of OxyContin overdoses made front-page and network news, doctors, narcotics agents, regulators, industry executives, and lawmakers raced in, scrambling to slow the damage. Behind it all stood one of America's wealthiest families, and a drug company whose relentless promotion helped fuel the problem Written by award-winning journalist Barry Meier, whose special report in the New York Times triggered national interest in OxyContin, Pain Killer chronicles the rise of the multibillion dollar pain management industry and lays bare its excesses and abuses From the Pulitzer Prize–winning New York Times reporter who first exposed the roots of the opioid epidemic and the secretive world of the Sackler family behind Purdue Pharma, Pain Killer is the celebrated landmark story of corporate greed and government negligence that inspired an upcoming Netflix series. “This is the book that started it all. Barry Meier is a heroic reporter and Pain Killer is a muckraking classic.”—Patrick Radden Keefe, author of Empire of Pain Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In Pain Killer, Barry Meier tells the story of how Purdue turned OxyContin into a billion-dollar blockbuster. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. But Purdue launched an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. In Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy. Between 1999 And 2017, An Estimated 250,000 Americans Died From Overdoses Involving Prescription Painkillers, A Plague Ignited By The Aggressive Marketing Of Oxycontin By Its Maker, Purdue Pharma. Purdue, Owned By A Wealthy And Secretive Family--the Sacklers--knew Early On That Teenagers And Others Were Abusing Its Billion Dollar Wonder Drug. But Justice Department Officials Balked A Decade Ago When It Came To Meting Out Justice, Allowing An Opioid Crisis To Evolve Into A Catastrophe. Originally Published In 2003 And Hailed Since As Groundbreaking, Meier--in This Thoroughly Updated Edition--reveals New And Shocking Information About How Long The Drug Maker Knew About Oxycontin's Abuse, Even As It Marketed It Aggressively, And The Way Government Officials Passed Up Opportunities To Protect Hundreds Of Thousands Of Lives. Equal Parts Crime Thriller, Medical Detective Story, And Business Expos,� Pain Killer Is The Origin Story Of The Opioid Crisis, A Hard-hitting Look At How A Supposed Wonder Drug Became The Gateway Drug To A National Tragedy--provided By Publisher. Book Of The Dead -- Pill Hill -- The War Against Pain -- Secrets Of Dendur -- A Pot Of Gold -- Senior Night -- Hot Spots -- Kiddie Dope -- Purple Peelers -- The Body Count -- A Reckoning -- Empire Of Deceit -- The War Against Pain Revisited. Barry Meier. Includes Bibliographical References (pages 195-209) And Index. "Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by the aggressive marketing of OxyContin by its maker, Purdue Pharma. Purdue, owned by a wealthy and secretive family--the Sacklers--knew early on that teenagers and others were abusing its billion dollar "wonder" drug. But Justice Department officials balked a decade ago when it came to meting out justice, allowing an opioid crisis to evolve into a catastrophe. Originally published in 2003 and hailed since as groundbreaking, Meier--in this thoroughly updated edition--reveals new and shocking information about how long the drug maker knew about OxyContin's abuse, even as it marketed it aggressively, and the way government officials passed up opportunities to protect hundreds of thousands of lives. Equal parts crime thriller, medical detective story, and business expos, ̌ Pain Killer is the origin story of the opioid crisis, a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy"-- Provided by publisher Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by the aggressive marketing of OxyContin by its maker, Purdue Pharma. Purdue, owned by a wealthy and secretive family--the Sacklers--knew early on that teenagers and others were abusing its billion dollar "wonder" drug. But Justice Department officials balked a decade ago when it came to meting out justice, allowing an opioid crisis to evolve into a catastrophe. Originally published in 2003 and hailed since as groundbreaking, Meier--in this thoroughly updated edition--reveals new and shocking information about how long the drug maker knew about OxyContin's abuse, even as it marketed it aggressively, and the way government officials passed up opportunities to protect hundreds of thousands of lives. Equal parts crime thriller, medical detective story, and business exposˇ, Pain Killer is the origin story of the opioid crisis, a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy"--Provided by publisher "Groundbreaking . . . the shocking account of the origins of today's opioid epidemic, the creators of this plague, and the way to help stop it."—Sam Quinones, author of Dreamland: The True Tale of America's Opiate Epidemic "Prescient . . . a landmark work of investigative journalism."—David A. Kessler, former commissioner of the Food and Drug Administration and author of The End of Overeating Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma's aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. In Pain Killer, Pulitzer Prize–winning New York Times reporter Barry Meier exposes the roots of the most pressing health epidemic of the twenty-first century. Powerful narcotic painkillers, or opioids, were once used as...