Oxygen Transport to Tissue XXXVIII (Advances in Experimental Medicine and Biology Book 923)

This book contains the refereed contributions from the 43rd annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. ISOTT conferences are a place where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The proceedings include sessions covered various research topics including Multi-Modal Imaging/Spectroscopy & Instrumentation; Cancer Metabolism; Cellular Hypoxia and Mitochondrial Function; Brain Oxygenation and Function; Other Organ Function and Metabolism; Oxygen Transport in Sports, Diseases and Clinical Care; Acupuncture, Meridians, and Primo Vascular System; EPR, MRS and MRI. Front Matter....Pages i-xxxix ISOTT from the Beginning: A Tribute to Our Deceased Members (Icons)....Pages 1-12 Front Matter....Pages 13-13 A Compelling Case for the Use of Perioperative Zymogen Protein C for Increased Patient Safety....Pages 15-21 Clinical Evaluation of MP4CO: A Phase 1b Escalating-Dose, Safety and Tolerability Study in Stable Adult Patients with Sickle Cell Disease....Pages 23-29 Protective Effect of Dl-3-n-Butylphthalide on Recovery from Cardiac Arrest and Resuscitation in Rats....Pages 31-36 Hypoxia-Induced Let-7d Has a Role in Pericyte Differentiation....Pages 37-42 Magnification of Cholesterol-Induced Membrane Resistance on the Tissue Level: Implications for Hypoxia....Pages 43-50 Respiratory Pores on Ostrich Struthio camelus (Aves: Struthionidae) Eggshells....Pages 51-55 Evaluation of Both Free Radical Scavenging Capacity and Antioxidative Damage Effect of Polydatin....Pages 57-62 Spectroscopic Studies on the Interaction of Pyridinoline Cross-Linking in Type 1 Collagen with ZIF8-HB....Pages 63-67 The Role of Free Radicals in the Photodynamic Treatment of Fibrotic Skin Diseases....Pages 69-74 Front Matter....Pages 75-75 Tumor Hypoxia: Causative Mechanisms, Microregional Heterogeneities, and the Role of Tissue-Based Hypoxia Markers....Pages 77-86 Molecular Imaging of Tumor Hypoxia: Existing Problems and Their Potential Model-Based Solutions....Pages 87-93 Direct and Repeated Clinical Measurements of pO2 for Enhancing Cancer Therapy and Other Applications....Pages 95-104 Impact of the Tumor Microenvironment on the Expression of Inflammatory Mediators in Cancer Cells....Pages 105-111 Comparing the Effectiveness of Methods to Measure Oxygen in Tissues for Prognosis and Treatment of Cancer....Pages 113-120 Potential Indexing of the Invasiveness of Breast Cancer Cells by Mitochondrial Redox Ratios....Pages 121-127 Directional Migration of MDA-MB-231 Cells Under Oxygen Concentration Gradients....Pages 129-134 Stress-Induced Stroke and Stomach Cancer: Sex Differences in Oxygen Saturation....Pages 135-140 Front Matter....Pages 141-141 Changes in Oxygenation Levels Precede Changes in Amplitude of the EEG in Premature Infants....Pages 143-149 Effects of Positive and Negative Mood Induction on the Prefrontal Cortex Activity Measured by Near Infrared Spectroscopy....Pages 151-157 Front Matter....Pages 141-141 Correlation Between the Cerebral Oxyhaemoglobin Signal and Physiological Signals During Cycling Exercise: A Near-Infrared Spectroscopy Study....Pages 159-166 Effect of Locomotor Respiratory Coupling Induced by Cortical Oxygenated Hemoglobin Levels During Cycle Ergometer Exercise of Light Intensity....Pages 167-172 Hypoxia and Neonatal Haemorrhagic Stroke: Experimental Study of Mechanisms....Pages 173-179 Interrelationship Between Broadband NIRS Measurements of Cerebral Cytochrome C Oxidase and Systemic Changes Indicates Injury Severity in Neonatal Encephalopathy....Pages 181-186 PFC Activity Pattern During Verbal WM Task in Healthy Male and Female Subjects: A NIRS Study....Pages 187-193 Spatial Distribution of Changes in Oxidised Cytochrome C Oxidase During Visual Stimulation Using Broadband Near Infrared Spectroscopy Imaging....Pages 195-201 Effects of Physical Exercise on Working Memory and Prefrontal Cortex Function in Post-Stroke Patients....Pages 203-208 Relation Between Prefrontal Cortex Activity and Respiratory Rate During Mental Stress Tasks: A Near-Infrared Spectroscopic Study....Pages 209-214 Effects of Antioxidant Supplements (BioPQQTM) on Cerebral Blood Flow and Oxygen Metabolism in the Prefrontal Cortex....Pages 215-222 Temporal Comparison Between NIRS and EEG Signals During a Mental Arithmetic Task Evaluated with Self-Organizing Maps....Pages 223-229 The Role of Phonological Processing in Semantic Access of Chinese Characters: A Near-Infrared Spectroscopy Study....Pages 231-237 Improvement of Impaired Cerebral Microcirculation Using Rheological Modulation by Drag-Reducing Polymers....Pages 239-244 Relationship Between Cerebral Oxygenation and Metabolism During Rewarming in Newborn Infants After Therapeutic Hypothermia Following Hypoxic-Ischemic Brain Injury....Pages 245-251 Front Matter....Pages 253-253 Low Volume Aerobic Training Heightens Muscle Deoxygenation in Early Post-Angina Pectoris Patients....Pages 255-261 The Effects of Passive Cycling Exercise for 30 min on Cardiorespiratory Dynamics in Healthy Men....Pages 263-268 Regional Differences of Metabolic Response During Dynamic Incremental Exercise by 31P-CSI....Pages 269-274 Muscle Deoxygenation and Its Heterogeneity Changes After Endurance Training....Pages 275-281 Response of BAX, Bcl-2 Proteins, and SIRT1/PGC-1α mRNA Expression to 8-Week Treadmill Running in the Aging Rat Skeletal Muscle....Pages 283-289 Muscle Oxygen Dynamics During Cycling Exercise in Angina Pectoris Patients....Pages 291-297 Front Matter....Pages 299-299 Chronological Review on Scientific Findings of Bonghan System and Primo Vascular System....Pages 301-309 Front Matter....Pages 299-299 Temporal Change of Alcian Blue-Stained Primo Vascular System in Lymph Vessels of Rats....Pages 311-317 Ultrastructure of the Subcutaneous Primo-Vascular System in Rat Abdomen....Pages 319-325 Effects of Acupuncture Stimulation on Muscle Tissue Oxygenation at Different Points....Pages 327-333 Front Matter....Pages 335-335 Continuous Wave Spectroscopy with Diffusion Theory for Quantification of Optical Properties: Comparison Between Multi-distance and Multi-wavelength Data Fitting Methods....Pages 337-343 Multi-modality Optical Imaging of Rat Kidney Dysfunction: In Vivo Response to Various Ischemia Times....Pages 345-350 Skeletal Muscle Oxygenation Measured by EPR Oximetry Using a Highly Sensitive Polymer-Encapsulated Paramagnetic Sensor....Pages 351-357 Determination of Optical and Microvascular Parameters of Port Wine Stains Using Diffuse Reflectance Spectroscopy....Pages 359-365 EPR Oximetry for Investigation of Hyperbaric O2 Pre-treatment for Tumor Radiosensitization....Pages 367-374 Design of a Compact, Bimorph Deformable Mirror-Based Adaptive Optics Scanning Laser Ophthalmoscope....Pages 375-383 Development of Portable, Wireless and Smartphone Controllable Near-Infrared Spectroscopy System....Pages 385-392 Monitoring the Oxygen Dynamics of Brain Tissue In Vivo by Fast Acousto-Optic Scanning Microscopy: A Proposed Instrument....Pages 393-399 Magnetization Transfer MRI Contrast May Correlate with Tissue Redox State in Prostate Cancer....Pages 401-406 Comparison of Two Algorithms for Analysis of Perfusion Computed Tomography Data for Evaluation of Cerebral Microcirculation in Chronic Subdural Hematoma....Pages 407-412 MMP-14 Triggered Fluorescence Contrast Agent....Pages 413-419 Boundary Element Method for Reconstructing Absorption and Diffusion Coefficients of Biological Tissues in DOT/MicroCT Imaging....Pages 421-426 Mathematical Model of an Innate Immune Response to Cutaneous Wound in the Presence of Local Hypoxia....Pages 427-433 Analytical Expression for the NO Concentration Profile Following NONOate Decomposition in the Presence of Oxygen....Pages 435-441 Back Matter....Pages 443-453 Qingming Luo, Lin Z. Li, David K. Harrison, Hua Shi, Duane F. Bruley, Editors. Includes Bibliographical References And Index.