Oxygen Transport to Tissue XXXIV (Advances in Experimental Medicine and Biology Book 765)

From the 39th annual conference of the International Society on Oxygen Transport to Tissue (ISOTT), held in Washington, DC, USA in July 2011, this volume covers aspects of oxygen transport from air to the cells, organs and organisms; instrumentation and methods to sense oxygen and clinical evidence. This volume of Oxygen Transport to Tissues studies near infrared spectroscopy, brain oxygenation, tumor biology, angiogenesis and mitochondrial metabolism, systems modeling, gas transport, kidney and exercise physiology. Emphasis is placed on methods of oxygen measurement in living tissue and application of these technologies to understanding physiological and biological bases for pathology related to tissue oxygenation. This multidisciplinary volume includes contributions from scientists (physicists, biologists and chemists), engineers, clinicians and mathematicians Front Matter....Pages i-xxx Effects of Experimentally Deviated Mandibular Position on Stress Response....Pages 1-7 Kidney EPO Expression During Chronic Hypoxia in Aged Mice....Pages 9-14 Nature’s “Silver Bullet” for Anticoagulation: Mechanism of Zymogen Protein C to Activated Protein C....Pages 15-21 Canonical Correlation Analysis in the Study of Cerebral and Peripheral Haemodynamics Interrelations with Systemic Variables in Neonates Supported on ECMO....Pages 23-29 Blood Oxygen Level Dependent Magnetization Transfer (BOLDMT) Effect....Pages 31-37 Characterizing Prostate Tumor Mouse Xenografts with CEST and MT-MRI and Redox Scanning....Pages 39-45 In Vitro Sirius Red Collagen Assay Measures the Pattern Shift from Soluble to Deposited Collagen....Pages 47-53 Intravoxel Incoherent Motion MR Imaging of the Kidney: Pilot Study....Pages 55-58 Changes in Gastric Mucosa, Submucosa, and Muscularis IC pH May Herald Irreversible Tissue Injury....Pages 59-65 Normobaric Hyperoxia Does Not Change Optical Scattering or Pathlength but Does Increase Oxidised Cytochrome c Oxidase Concentration in Patients with Brain Injury....Pages 67-72 Multi-frequency Forced Oscillation Technique Using Impulse Oscillations: Can It Give Mechanical Information about the Lung Periphery?....Pages 73-79 NIRS Measurements with Elite Speed Skaters: Comparison Between the Ice Rink and the Laboratory....Pages 81-86 Modelling Cerebrovascular Reactivity: A Novel Near-Infrared Biomarker of Cerebral Autoregulation?....Pages 87-93 Oxygen Delivery Deficit in Exercise with Rapid Ascent to High Altitude....Pages 95-99 Oscillations in Cerebral Haemodynamics in Patients with Falciparum Malaria....Pages 101-107 Effect of Spinal Anesthesia for Elective Cesarean Section on Cerebral Blood Oxygenation Changes: Comparison of Hyperbaric and Isobaric Bupivacaine....Pages 109-114 DCX-Expressing Neurons Decrease in the Retrosplenial Cortex after Global Brain Ischemia....Pages 115-121 Calibration and Validation Scheme for In Vivo Spectroscopic Imaging of Tissue Oxygenation....Pages 123-129 Considering the Vascular Hypothesis of Alzheimer’s Disease: Effect of Copper Associated Amyloid on Red Blood Cells....Pages 131-138 The Role of Mitochondrial Proteomic Analysis in Radiological Accidents and Terrorism....Pages 139-145 Alteration of Plasma Galactose/ N -acetylgalactosamine Level After Irradiation....Pages 147-153 Fibroblast Growth Factor-Peptide Promotes Bone Marrow Recovery After Irradiation....Pages 155-161 Dynamic Two-Photon Imaging of Cerebral Microcirculation Using Fluorescently Labeled Red Blood Cells and Plasma....Pages 163-168 The Effect of Basic Assumptions on the Tissue Oxygen Saturation Value of Near Infrared Spectroscopy....Pages 169-175 The Effect of Sudden Depressurization on Pilots at Cruising Altitude....Pages 177-183 Hypoxia in the Diabetic Kidney Is Independent of Advanced Glycation End-Products....Pages 185-193 Tumor Oxygen Measurements and Personalized Medicine....Pages 195-201 Wavelet Cross-Correlation to Investigate Regional Variations in Cerebral Oxygenation in Infants Supported on Extracorporeal Membrane Oxygenation....Pages 203-209 Association of the Red Cell Distribution Width with Red Blood Cell Deformability....Pages 211-216 Kidney Function After In Vivo Gene Silencing of Uncoupling Protein-2 in Streptozotocin-Induced Diabetic Rats....Pages 217-223 Adenosine A2 Receptor-Mediated Regulation of Renal Hemodynamics and Glomerular Filtration Rate Is Abolished in Diabetes....Pages 225-230 Can Mitochondrial Cytochrome Oxidase Mediate Hypoxic Vasodilation Via Nitric Oxide Metabolism?....Pages 231-238 Effects of Occlusal Disharmony on Working Memory Performance and Prefrontal Cortex Activity Induced by Working Memory Tasks Measured by NIRS....Pages 239-244 Biological Maintenance of Distal Vein Arterialization....Pages 245-250 Bayesian STAI Anxiety Index Predictions Based on Prefrontal Cortex NIRS Data for the Resting State....Pages 251-256 The Effect of Venous and Arterial Occlusion of the Arm on Changes in Tissue Hemodynamics, Oxygenation, and Ultra-Weak Photon Emission....Pages 257-264 Metabolic Network Analysis of DB1 Melanoma Cells: How Much Energy Is Derived from Aerobic Glycolysis?....Pages 265-271 Muscle Oxygen Saturation Heterogeneity Among Leg Muscles During Ramp Exercise....Pages 273-278 PET Imaging of the Impact of Extracellular pH and MAP Kinases on the p -Glycoprotein (Pgp) Activity....Pages 279-286 Meconium and Transitional Stools May Cause Interference with Near-Infrared Spectroscopy Measurements of Intestinal Oxygen Saturation in Preterm Infants....Pages 287-292 Acute Effects of Physical Exercise on Prefrontal Cortex Activity in Older Adults: A Functional Near-Infrared Spectroscopy Study....Pages 293-298 Blood Flow and Oxygenation Status of Prostate Cancers....Pages 299-305 Targeted Delivery of VEGF to Treat Myocardial Infarction....Pages 307-314 Magnetic Nanoparticles and Thermally Responsive Polymer for Targeted Hyperthermia and Sustained Anti-Cancer Drug Delivery....Pages 315-321 NIR Fluorophore-Hollow Gold Nanosphere Complex for Cancer Enzyme-Triggered Detection and Hyperthermia....Pages 323-328 Renal Oxygenation and Function of the Rat Kidney: Effects of Inspired Oxygen and Preglomerular Oxygen Shunting....Pages 329-334 Alteration of the Inflammatory Molecule Network After Irradiation of Soft Tissue....Pages 335-341 Imaging the Redox States of Human Breast Cancer Core Biopsies....Pages 343-349 Early Life Hypoxic or Hypoxic/Hypercapnic Stress Alters Acute Ventilatory Sensitivity in Adult Mice....Pages 351-355 3D Analysis of Intracortical Microvasculature During Chronic Hypoxia in Mouse Brains....Pages 357-363 Contribution of Brain Glucose and Ketone Bodies to Oxidative Metabolism....Pages 365-370 Alteration of Circulating Mitochondrial DNA Concentration After Irradiation....Pages 371-377 Back Matter....Pages 379-385