Oxygen Transport To Tissue - Ii (advances In Experimental Medicine And Biology)

Front Matter....Pages N1-xxiii Front Matter....Pages 1-1 A Method for Simultaneous Measurements of Bioelectric Activity and Local Tissue PO 2 in the CNS....Pages 3-7 Oxygen Fields Induced by Recessed and Needle Oxygen Microelectrodes in Homogeneous Media....Pages 9-16 The Application of Histological Analysis for the Localization of Tissue PO 2 and Local Blood Flow with the Example of the Glomus Caroticum of the Rabbit (Oryctolagus Cuniculus)....Pages 17-23 A Method for Measuring Oxygen Uptake Rate Distributions Over the Surface Zone of Excised Tissues Using a 91-Cathode Electrode....Pages 25-32 Monitoring of PO 2 in Human Blood....Pages 33-40 A New Approach to the Experimental Measurement of Mean Tissue PO 2 ....Pages 41-46 Pyrene Butyric Acid: A Non-Invasive Probe for In Situ Intracellular Oxygen Concentration....Pages 47-54 Kryomicrophotometry as a Method for Analyzing the Intracapillary HbO 2 Saturation of Organs Under Different O 2 Supply Conditions....Pages 55-64 Quantitative Fluorescence Photometry with Biological Fluids and Gases....Pages 65-68 Control of Electrode Aging by a Periodic Anodization Technique....Pages 69-75 Front Matter....Pages 79-79 Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes....Pages 81-88 The Effect of Red Cell 2,3-DPG Changes Induced by Diabetic Ketoacidosis on Parameters of the Oxygen Dissociation Curve in Man....Pages 89-95 The Influence of MgCl 2 on the O 2 -Hb-Binding Curve of Human Hemoglobin Under Intracellular Conditions....Pages 97-103 Oxygen Transport and Hemodynamics of Stroma-Free Hemoglobin Solutions....Pages 105-112 Oxygen Transport on Mount Everest: The Effects of Increased Hematocrit on Maximal O 2 Transport....Pages 113-119 Measurement of Oxygenation and Deoxygenation of a Single Red Cell of Chicken Embryo by Means of a Microphotometer....Pages 121-130 Front Matter....Pages 135-135 Cellular Control of Mitochondrial Respiration....Pages 137-144 Influence of Hemoglobin Oxygen Affinity on Oxidation Reduction State of Cytochrome aa 3 in Perfused Liver....Pages 145-150 Problems in Determination of Oxygen Dissociation of Avian Blood....Pages 151-158 Metabolic and Electron Microscopic Studies Post Mortem in Brain Mitochondria....Pages 159-164 Front Matter....Pages 135-135 Early Structural Changes in Mitochondria in Response to Acute Reductions in Capillary Flow....Pages 165-170 The Induction of Cytochrome P-450 by Hypoxia....Pages 171-175 Front Matter....Pages 181-181 Diffusion of Oxygen in Plasma and Blood....Pages 183-190 Facilitated Diffusion of Oxygen in Red Blood Cell Suspensions....Pages 191-198 Measurement of Diffusivity and Metabolic Rate of O 2 and CO 2 in Respiring Tissue....Pages 199-206 Facilitated Diffusion of CO and Oxygen in the Presence of Hemoglobin or Myoglobin....Pages 207-215 The Measurement of the Fraction of Oxygen Carried by Facilitated Diffusion....Pages 217-223 Measurement of Diffusion Parameters with Noble Metal Electrodes....Pages 225-228 Front Matter....Pages 231-231 A Generalized Advancing front Model Describing the Oxygen Transfer in Flowing Blood....Pages 233-240 A Theoretical Model of the Respiratory Function of Blood....Pages 241-249 Some Model Results on Hemoglobin Kinetics and Its Relationship to Oxygen Transport in Blood....Pages 251-259 The Mechanical Basis for Fick’s Law and Its Generalizations....Pages 261-265 A Stochastic Model for the Transport of Oxygen to Brain Tissue....Pages 267-277 Models for O 2 and CO 2 Transfer in Macroscopic Flow Channels and Their Physiological Implications....Pages 279-284 Front Matter....Pages 287-287 Correlation between the Redox State, Electrical Activity and Blood Flow in Cat Brain CORTEX During Hemorrhagic Shock....Pages 289-297 Cortical NADH, pO 2 , Electrical Activity and Arterial Blood Pressure Oscillations in Hypoxaemia....Pages 299-305 The Effect of Decapitation on the Oxidation-Reduction State of NADH and ECoG in the Brain of the Awake Rat....Pages 307-312 Cerebral Oxygen Supply in Brain Edema and During Ventriculo-Cisternal Perfusion....Pages 313-324 Tissue Responses to Hypoxia, Shock and Stroke....Pages 325-333 Cerebral Oxygenation in Arterial Hypoxia....Pages 335-342 Front Matter....Pages 287-287 Theoretical and Experimental Aspects of Brain Tissue Oxygenation Dynamics....Pages 343-354 Front Matter....Pages 359-359 Local Tissue Po 2 and Microflow of the Brain Cortex Under Varying Arterial Oxygen Pressure....Pages 361-367 An Analysis of Ion Distribution in Brain Following Anoxia....Pages 369-374 Comparison of Oxygen Tension in the Spinal Cord and Globus Pallidus During Hyperbaric Oxygen Exposure of Rats Under Pentobarbital Anesthesia....Pages 375-382 Autonomic and Pharmacological Control of Oxygen Autoregulation Mechanisms in Brain Tissue....Pages 383-389 Effects of So-Called “Cerebral Blood Flow Increasing” Drugs on Tissue-Oxygenation of the Brain....Pages 391-398 Front Matter....Pages 403-403 Oxygen Supply to the Open Rabbit Cornea....Pages 405-412 Studies on Retinal Oxygenation....Pages 413-416 A System for in Vivo Measurement of Oxygen in Intraocular Tissue....Pages 417-424 The O 2 Supply of the Isolated Cell-Free Perfused Rat Kidney....Pages 425-432 Effect of Vasopressors and Hemorrhage on Intrarenal Oxygenation....Pages 433-439 Renal Tissue Oxygenation During Hypoxic Hypoxia....Pages 441-447 Corneal Oxygen Supply Conditions....Pages 449-455 Front Matter....Pages 461-461 Cellular Oxygen Concentration....Pages 463-467 The Role of Carotid Chemoreceptors in the Regulation of Arterial Oxygen Transport under Hypoxia with and without Hypercapnia....Pages 469-476 Pulmonary Tissue Oxygen Requirement....Pages 477-482 Oxygen Delivery and Utilization in Hypoxic Dogs Made Acidemic and Alkalemic....Pages 483-489 Evidence Against Local Control of Intestinal Tissue Oxygenation by Myogenic Mechanisms....Pages 491-496 Effect of Ionizing Radiation on Liver Microcirculation and Oxygenation....Pages 497-503 A Factor in Longitudinal Tissue Gradients: Red Cell Carriage....Pages 505-510 Front Matter....Pages 461-461 Effects of Dopamine and Epinephrine on Intestinal Blood Flow and Oxygen Uptake....Pages 511-516 Front Matter....Pages 519-519 In Vivo Utilization of Oxygen and Glucose by Neoplastic Tissue....Pages 521-536 O 2 Supply Conditions in Tumor Tissue in Vivo....Pages 537-546 Pathophysiological Aspects of Glucose Uptake by the Tumor Tissue under Various Conditions of Oxygen and Glucose Supply....Pages 547-553 Solution of the Diffusion Field Equation of Substrate Concentration in the Intercapillary Region Considering the Decrease in Substrate Consumption in the Unsaturated Region of Cancer Cell Glycolysis and Respiration....Pages 555-562 Computation of Glucose and O 2 Concentration Distribution in the Intercapillary Region of Intact Tumor Tissue Considering the Decrease in Substrate Consumption in the Unsaturated Region of Cancer Cell Glycolysis and Respiration....Pages 563-570 Mesenchyme Theory on the Increase in Resistance Experienced During Repetition of Cancer Therapy Processes....Pages 571-575 Front Matter....Pages 579-579 Studies on the Ability of the Tumor Respiration in Vivo to Fulfill its Physiological Functions....Pages 581-586 Control Mechanisms of Oxygen and Glucose Utilization in Tumours....Pages 587-596 Oxygen Distribution in Tumours: Influence on Cell Proliferation and Implications for Tumour Therapy....Pages 597-603 Preliminary Observations of Oxygen Levels in Microcirculation of Tumors in C3H Mice....Pages 605-610 The Distribution of Oxygen Consumption Rates in Some Tissues before and after X-Irradiation....Pages 611-617 Front Matter....Pages 621-621 Mechanisms of Circulation Metabolism Coupling in Skeletal Muscle....Pages 623-630 Spontaneous Oscillations of PO 2 in Muscle Tissue....Pages 631-637 Tissue PO 2 , VO 2 , Venous PO 2 and Perfusion Pressure in Resting Dog Gracilis Muscle Perfused at Constant Flow....Pages 639-655 Effect of a Shift of the Oxygen Dissociation Curve on Myocardial Oxygenation at Hypoxia....Pages 657-662 Tissue Blood Flow and Oxygenation during Large Vessel Surgery....Pages 663-666 Mechanisms of Increased Tissue Oxygen Delivery Following Release of Arterial Occlusion in Canine Skeletal Muscle and Skin....Pages 667-674 Mean Myoglobin Oxygen Tension during Exercise at Maximal Oxygen Uptake....Pages 675-683 Oxygen Transport in Skeletal Muscle: Capillary Geometry in Longitudinal Section....Pages 685-692 Front Matter....Pages 621-621 The Measurement of Myocardial Microflow and Its Reaction to Hypoxia and Hypercapnia....Pages 693-698 Front Matter....Pages 703-703 Oxygen Uptake of the Guinea Pig at Decreased and Increased Maternal Placental Blood Flow....Pages 705-712 Development and Adaptation of Heart Mitochondrial Respiratory Chain Function in Fetus and in Newborn....Pages 713-719 Experimental and Theoretical Analysis of Oxygen Transport in Fetal Brain....Pages 721-730 Fetal and Placental O 2 Consumption and the Uptake of Different Metabolites in the Ruminant and Horse during Late Gestation....Pages 731-736 Continuous PO 2 and Heart Rate Recording in the Human Newborn....Pages 737-745 A Comparison of Transcutaneous and Arterial PO 2 in Sick Neonates....Pages 747-752 Effect of Umbilical Artery Catheters on Oxygen Supply to Extremities....Pages 753-757 Tissue Oxygen Available (O 2 a) as a Criterion for the Effectiveness of Continuous Positive Pressure Breathing (CPPB)....Pages 759-763 Back Matter....Pages 769-781