Oxford Textbook of Neuro-Oncology (Oxford Textbooks in Clinical Neurology)

The __Oxford Textbook of Neuro-Oncology__ examines the epidemiology, pathogenesis, clinical features, and management of adult and childhood central nervous system (CNS) tumours. The book is organized according to the World Health Organization (WHO) classification of CNS tumours and includes an introductory chapter discussing the new, revised WHO classification that will be used in future editions of this textbook. The book reviews primary CNS tumours, metastatic CNS tumours, and familial tumour syndromes. Each chapter is organized according to a uniform framework, addressing epidemiology, aetiology, pathogenesis, clinical presentation, imaging, and treatment, with a focus on different treatment modalities and specific consideration of paediatric aspects, where applicable. Each chapter is authored by a multidisciplinary, international group of senior specialists representing the United States, Canada, Europe, and the Asia/Pacific region. It is written for generalists and specialists managing these various conditions. It provides an outlook on how current developments in molecular diagnostics, which have in part been integrated into the new WHO classification, may shape clinical decision-making in the future. Cover Foreword Preface Contents Abbreviations Contributors Plates 1 The 2016 revision of the WHO classification of tumours of the central nervous system 2 Astrocytic tumours: pilocytic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma 3 Astrocytic tumours: diffuse astrocytoma, anaplastic astrocytoma, glioblastoma, and gliomatosis cerebri 4 Oligodendroglial tumours 5 Ependymal tumours 6 Choroid plexus tumours 7 Other neuroepithelial tumours: astroblastoma, angiocentric glioma, and chordoid glioma 8 Neuronal and mixed neuronal–​glial tumours 9 Embryonal and pineal tumours 10 Tumours of the cranial nerves 11 Meningiomas 12 Other tumours of the meninges 13 Tumours of the haematopoietic system 14 Germ cell tumours 15 Familial tumour syndromes: neurofibromatosis, schwannomatosis, rhabdoid tumour predisposition, Li–​Fraumeni syndrome, Turcot syndrome, Gorlin syndrome, and Cowden syndrome 16 Familial tumour syndromes: von Hippel–​Lindau disease 17 Familial tumour syndromes: tuberous sclerosis complex 18 Pituitary tumours 19 Metastatic brain tumours 20 Metastatic tumours: spinal cord, plexus, and peripheral nerve 21 Neoplastic meningitis: metastases to the leptomeninges and cerebrospinal fluid Index Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuro-Oncology covers the pathophysiology, diagnosis, classification, and management of tumours of the nervous system. The book provides a comprehensive overview of tumour subtypes, in accordance with WHO classifications, along with management plans for adult and paediatric populations. The international team of co-editors ensures that expert commentaries on existing and wide-reaching diagnostic and treatment guidelines (including NCCN and ESMO) are accessible by a global audience. Part of the 'Oxford Textbooks in Clinical Neurology' series, this volume covers the pathophysiology, diagnosis, classification, and management of tumours of the nervous system