Oxford Handbook of Rheumatology (Oxford Medical Handbooks)

Extensively revised and fully updated, this new edition of the Oxford Handbook of Rheumatology provides everything you need to understand the wide range of rheumatic conditions. Including the latest guidelines and the most up-to-date information, this is the indispensible guide for students, trainees, consultant rheumatologists, and everyone dealing with patients with musculoskeletal disease. Rheumatic conditions are common in both general and hospital practice; a primary feature of many multi-system illnesses, and in the context of injury, age-related change, and psychological distress. This handbook provides practical advice, guidance, and key clinical facts to help you provide the best care for your patients. Practically structured, the handbook focuses first on presenting symptoms, and then considers key diseases, emergencies, and rare diseases in more detail, finishing with a comprehensive account of assessment, guidelines, and treatment options including the latest advances in biological therapy. It provides practical guidelines on the management and diagnosis of patients with acute and chronic musculoskeletal disease. Colour plates and line drawings are present throughout along with tables of key information. Taking a clinical, evidence-based approach, written by experts, and presented in a clear, practical, bullet-point style for rapid reference, this handbook will be your constant companion and a joy to use. Cover Contents Editorial advisers Symbols and abbreviations Part I: The presentation of rheumatic disease 1 Evaluating musculoskeletal symptoms Introduction Localization of pain and pain patterns Changes in pain on examination The assessment of pain in young children Stiffness, swelling, and constitutional symptoms Gait, arms, legs, spine—the GALS screen 2 Regional musculoskeletal conditions: making a working diagnosis Introduction Neck pain Shoulder pain Pain around the elbow Wrist pain Symptoms in the hand Upper limb peripheral nerve lesions Thoracic back and chest pain Low back pain and disorders in adults Spinal disorders in children and adolescents Pelvic, groin, and thigh pain Knee pain Lower leg and foot disorders (adults) Child and adolescent foot disorders 3 Patterns of disease presentation: making a working diagnosis Mono-articular pain in adults Oligo-articular pain in adults Oligo-articular and pauci-articular pain in children and adolescents Widespread pain in adults Widespread pain in children and adolescents 4 The spectrum of non-musculoskeletal disorders in rheumatic disease Skin disorders and rheumatic disease Skin vasculitis in adults Skin vasculitis in children and adolescents Cardiac manifestations Pulmonary manifestations Renal manifestations Endocrine manifestations Gut and hepatobiliary manifestations Malignancy Neurological disorders Part II: The clinical features and management of rheumatic diseases 5 Rheumatoid arthritis Disease criteria and epidemiology for use in clinical trials Incidence, prevalence, and morbidity The clinical features of rheumatoid arthritis Organ disease in rheumatoid arthritis The evaluation and treatment of rheumatoid arthritis Polyarticular arthritis in children with a positive rheumatoid factor Still’s disease 6 Osteoarthritis Introduction Clinical features of osteoarthritis The investigation of osteoarthritis The management of osteoarthritis 7 The crystal arthropathies Gout and hyperuricaemia Calcium pyrophosphate dihydrate disease Basic calcium phosphate associated disease Calcium oxalate arthritis 8 The spondyloarthropathies Introduction Diagnostic criteria and clinical subsets Ankylosing spondylitis Psoriatic arthritis Reactive arthropathy Enteric arthropathy Spondyloarthropathies in childhood 9 Juvenile idiopathic arthritis Introduction Oligoarthritis Systemic arthritis Rheumatoid factor negative polyarthritis in childhood Chronic, infantile, neurological, cutaneous, and articular syndrome 10 Systemic lupus erythematosus Introduction The clinical features of systemic lupus erythematosus Antiphospholipid (antibody) syndrome and systemic lupus erythematosus Pregnancy and systemic lupus erythematosus Diagnosis and investigation of systemic lupus erythematosus Drug-induced lupus erythematosus The treatment of systemic lupus erythematosus Prognosis and survival in systemic lupus erythematosus Childhood systemic lupus erythematosus Neonatal systemic lupus erythematosus 11 The antiphospholipid (antibody) syndrome Introduction Epidemiology and pathology Clinical features of antiphospholipid syndrome Treatment of antiphospholipid syndrome Catastrophic antiphospholipid syndrome 12 Sjögren’s syndrome Epidemiology and pathology Clinical manifestations of Sjögren’s syndrome Investigation of Sjögren’s syndrome Treatment of Sjögren’s syndrome 13 Systemic sclerosis and related disorders Epidemiology and diagnostic critetria Cutaneous features of scleroderma and their treatment Systemic features of the disease, investigation, and treatment Antifibrotic and immunosuppressive therapies for systemic sclerosis Summary—the approach to systemic sclerosis Scleroderma-like fibrosing disorders 14 Idiopathic infiammatory myopathies: polymyositis and dermatomyositis Epidemiology and diagnosis Clinical features of polymyositis and dermatomyositis Investigation of polymyositis and dermatomyositis Autoantibodies in myositis Treatment of polymyositis and dermatomyositis Inclusion-body myositis Polymyositis and dermatomyositis in children 15 Primary vasculitides Introduction Large-vessel vasculitis Takayasu’s arteritis Polymyalgia rheumatica and giant cell arteritis Polyarteritis nodosa Wegener’s granulomatosis Other forms of antineutrophil cytoplasmic antibody-associated vasculitides: microscopic polyangiitis and the Churg–Strauss syndrome Small-vessel vasculitis Kawasaki disease 16 Metabolic bone diseases and disorders of collagen Osteoporosis Osteomalacia and rickets Parathyroid disease and related disorders Paget’s disease of bone Miscellaneous diseases of bone Molecular abnormalities of collagen and fibrillin 17 Infection and rheumatic disease Introduction Pyogenic non-gonococcal and gonococcal arthritides Mycobacterium tuberculosis Osteomyelitis Lyme disease Rheumatic fever 18 Miscellaneous conditions Behçet’s disease Sarcoidosis Miscellaneous skin conditions associated with arthritis Complex regional pain syndrome Relapsing polychondritis Miscellaneous disorders of synovium Amyloidosis Fibromyalgia and chronic widespread pain 19 Common upper limb musculoskeletal lesions Shoulder (subacromial) impingement syndrome Adhesive capsulitis Lateral epicondylitis (tennis elbow) 20 Back pain Categorizing of back pain Conditions causing acute or sub-acute back pain in adults Management of chronic back pain Management of back pain in children and adolescents Part III: Medicine management and emergencies 21 Drugs used in rheumatology Introduction Principles of rehabilitation Pain relief Opioid analgesics Non-steroidal anti-inflammatory drugs Antidepressants Anticonvulsants Glucocorticoids (Non-biologic) disease-modifying anti-rheumatic drugs Biologic therapies Other medication 22 Corticosteroid injection therapy Introduction Principles of injection techniques The shoulder The elbow The wrist and hand The hip and peri-articular lesions The knee and peri-articular lesions The ankle and foot 23 Complementary and alternative medicine in rheumatology Introduction Herbal remedies (phytotherapy) Physical and ‘hands-on’ therapies Homeopathy Other complementary and alternative medicines 24 Rheumatological emergencies Septic arthritis Infections in patients taking biologic therapy Acute systemic lupus erythematosus Systemic vasculitis Scleroderma crises Methotrexate-induced pneumonitis Index A B C D E F G H I J K L M N O P Q R S T U V W Y Z Extensively revised and fully updated, this new edition of the Oxford Handbook of Rheumatology provides everything you need to understand the wide range of rheumatic conditions. Including the latest guidelines and the most up-to-date information, this is the indispensible guide for students, trainees, consultant rheumatologists, and everyone dealing with patients with musculoskeletal disease. Rheumatic conditions are common in both general and hospital practice; a primary feature of many multi-system illnesses, and in the context of injury, age-related change, and psychological distress. This handbook provides practical advice, guidance, and key clinical facts to help you provide the best care for your patients. Practically structured, the handbook focuses first on presenting symptoms, and then considers key diseases, emergencies, and rare diseases in more detail, finishing with a comprehensive account of assessment, guidelines, and treatment options including the latest advances in biological therapy. It provides practical guidelines on the management and diagnosis of patients with acute and chronic musculoskeletal disease. Colour plates and line drawings are present throughout along with tables of key information. Taking a clinical, evidence-based approach, written by experts, and presented in a clear, practical, bullet-point style for rapid reference, this handbook will be your constant companion and a joy to use. -- Résumé de l'éditeur A unique pocket guide which emphasizes a clinical, evidence-based approach to rheumatology. The handbook provides practical guidelines to the management and diagnosis of patients with acute and chronic musculoskeletal disease.